Thorold W. Theunissen
Thorold W. Theunissen
Associate Professor of Developmental Biology at Washington University in St. Louis
Verified email at - Homepage
Cited by
Cited by
A protein interaction network for pluripotency of embryonic stem cells
J Wang, S Rao, J Chu, X Shen, DN Levasseur, TW Theunissen, SH Orkin
Nature 444 (7117), 364-368, 2006
Nanog is the gateway to the pluripotent ground state
J Silva, J Nichols, TW Theunissen, G Guo, AL van Oosten, O Barrandon, ...
Cell 138 (4), 722-737, 2009
Promotion of reprogramming to ground state pluripotency by signal inhibition
J Silva, O Barrandon, J Nichols, J Kawaguchi, TW Theunissen, A Smith
PLoS biology 6 (10), e253, 2008
Multiplexed activation of endogenous genes by CRISPR-on, an RNA-guided transcriptional activator system
AW Cheng, H Wang, H Yang, L Shi, Y Katz, TW Theunissen, ...
Cell research 23 (10), 1163-1171, 2013
Systematic identification of culture conditions for induction and maintenance of naive human pluripotency
TW Theunissen, BE Powell, H Wang, M Mitalipova, DA Faddah, J Reddy, ...
Cell stem cell 15 (4), 471-487, 2014
Molecular criteria for defining the naive human pluripotent state
TW Theunissen, M Friedli, Y He, E Planet, RC O’Neil, S Markoulaki, ...
Cell stem cell 19 (4), 502-515, 2016
NANOG-dependent function of TET1 and TET2 in establishment of pluripotency
Y Costa, J Ding, TW Theunissen, F Faiola, TA Hore, PV Shliaha, ...
Nature 495 (7441), 370-374, 2013
Prmt5 is essential for early mouse development and acts in the cytoplasm to maintain ES cell pluripotency
WW Tee, M Pardo, TW Theunissen, L Yu, JS Choudhary, P Hajkova, ...
Genes & development 24 (24), 2772-2777, 2010
Stat3 activation is limiting for reprogramming to ground state pluripotency
J Yang, AL Van Oosten, TW Theunissen, G Guo, JCR Silva, A Smith
Cell stem cell 7 (3), 319-328, 2010
Derivation of trophoblast stem cells from nave human pluripotent stem cells
C Dong, M Beltcheva, P Gontarz, B Zhang, P Popli, LA Fischer, SA Khan, ...
elife 9, e52504, 2020
A defined Oct4 level governs cell state transitions of pluripotency entry and differentiation into all embryonic lineages
A Radzisheuskaya, G Le Bin Chia, RL Dos Santos, TW Theunissen, ...
Nature cell biology 15 (6), 579-590, 2013
Hominoid-specific transposable elements and KZFPs facilitate human embryonic genome activation and control transcription in naive human ESCs
J Pontis, E Planet, S Offner, P Turelli, J Duc, A Coudray, TW Theunissen, ...
Cell stem cell 24 (5), 724-735. e5, 2019
Human naive pluripotent stem cells model X chromosome dampening and X inactivation
A Sahakyan, R Kim, C Chronis, S Sabri, G Bonora, TW Theunissen, ...
Cell stem cell 20 (1), 87-101, 2017
Nanog overcomes reprogramming barriers and induces pluripotency in minimal conditions
TW Theunissen, AL Van Oosten, G Castelo-Branco, J Hall, A Smith, ...
Current Biology 21 (1), 65-71, 2011
Molecular control of induced pluripotency
TW Theunissen, R Jaenisch
Cell stem cell 14 (6), 720-734, 2014
The transcriptional network controlling pluripotency in ES cells
SH Orkin, J Wang, J Kim, J Chu, S Rao, TW Theunissen, X Shen, ...
Cold Spring Harbor symposia on quantitative biology 73, 195-202, 2008
Reprogramming capacity of Nanog is functionally conserved in vertebrates and resides in a unique homeodomain
TW Theunissen, Y Costa, A Radzisheuskaya, AL van Oosten, F Lavial, ...
Development 138 (22), 4853-4865, 2011
Stem-cell-derived trophoblast organoids model human placental development and susceptibility to emerging pathogens
RM Karvas, SA Khan, S Verma, Y Yin, D Kulkarni, C Dong, K Park, ...
Cell Stem Cell 29 (5), 810-825. e8, 2022
Mechanisms of gene regulation in human embryos and pluripotent stem cells
TW Theunissen, R Jaenisch
Development 144 (24), 4496-4509, 2017
Switching on pluripotency: a perspective on the biological requirement of Nanog
TW Theunissen, JCR Silva
Philosophical Transactions of the Royal Society B: Biological Sciences 366…, 2011
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