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Cédric R Weber
Cédric R Weber
Laboratory for Systems and Synthetic Immunology, ETH Zurich
Verified email at bsse.ethz.ch - Homepage
Title
Cited by
Cited by
Year
Computational strategies for dissecting the high-dimensional complexity of adaptive immune repertoires
E Miho, A Yermanos, CR Weber, CT Berger, V Greiff
Frontiers in immunology 9, 330957, 2018
1832018
Optimization of therapeutic antibodies by predicting antigen specificity from antibody sequence via deep learning
DM Mason, S Friedensohn, CR Weber, C Jordi, B Wagner, SM Meng, ...
Nature Biomedical Engineering 5 (6), 600-612, 2021
1752021
Systems analysis reveals high genetic and antigen-driven predetermination of antibody repertoires throughout B cell development
V Greiff, U Menzel, E Miho, C Weber, R Riedel, S Cook, A Valai, T Lopes, ...
Cell reports 19 (7), 1467-1478, 2017
1672017
A compact vocabulary of paratope-epitope interactions enables predictability of antibody-antigen binding
R Akbar, PA Robert, M Pavlović, JR Jeliazkov, I Snapkov, A Slabodkin, ...
Cell Reports 34 (11), 2021
1482021
Learning the high-dimensional immunogenomic features that predict public and private antibody repertoires
V Greiff, CR Weber, J Palme, U Bodenhofer, E Miho, U Menzel, ST Reddy
The Journal of Immunology 199 (8), 2985-2997, 2017
1142017
In silico proof of principle of machine learning-based antibody design at unconstrained scale
R Akbar, PA Robert, CR Weber, M Widrich, R Frank, M Pavlović, ...
MAbs 14 (1), 2031482, 2022
812022
High-throughput antibody engineering in mammalian cells by CRISPR/Cas9-mediated homology-directed mutagenesis
DM Mason, CR Weber, C Parola, SM Meng, V Greiff, WJ Kelton, ...
Nucleic acids research 46 (14), 7436-7449, 2018
772018
Deep mutational learning predicts ACE2 binding and antibody escape to combinatorial mutations in the SARS-CoV-2 receptor-binding domain
JM Taft, CR Weber, B Gao, RA Ehling, J Han, L Frei, SW Metcalfe, ...
Cell 185 (21), 4008-4022. e14, 2022
69*2022
immuneSIM: tunable multi-feature simulation of B-and T-cell receptor repertoires for immunoinformatics benchmarking
CR Weber, R Akbar, A Yermanos, M Pavlović, I Snapkov, GK Sandve, ...
Bioinformatics 36 (11), 3594-3596, 2020
632020
The immuneML ecosystem for machine learning analysis of adaptive immune receptor repertoires
M Pavlović, L Scheffer, K Motwani, C Kanduri, R Kompova, N Vazov, ...
Nature Machine Intelligence 3 (11), 936-944, 2021
572021
Deep learning enables therapeutic antibody optimization in mammalian cells by deciphering high-dimensional protein sequence space
DM Mason, S Friedensohn, CR Weber, C Jordi, B Wagner, S Meng, ...
BioRxiv, 617860, 2019
512019
A single-cell atlas of lymphocyte adaptive immune repertoires and transcriptomes reveals age-related differences in convalescent COVID-19 patients
F Bieberich, RA Ehling, CR Weber, ST Reddy
Frontiers in immunology 12, 701085, 2021
392021
The future of blood testing is the immunome
RA Arnaout, ETL Prak, N Schwab, F Rubelt, ...
Frontiers in Immunology 12, 626793, 2021
312021
Individualized VDJ recombination predisposes the available Ig sequence space
A Slabodkin, M Chernigovskaya, I Mikocziova, R Akbar, L Scheffer, ...
Genome Research 31 (12), 2209-2224, 2021
302021
Platypus: an open-access software for integrating lymphocyte single-cell immune repertoires with transcriptomes
A Yermanos, A Agrafiotis, R Kuhn, D Robbiani, J Yates, C Papadopoulou, ...
NAR genomics and bioinformatics 3 (2), lqab023, 2021
282021
High-throughput T cell receptor engineering by functional screening identifies candidates with enhanced potency and specificity
R Vazquez-Lombardi, JS Jung, FS Schlatter, A Mei, NR Mantuano, ...
Immunity 55 (10), 1953-1966. e10, 2022
26*2022
SARS-CoV-2 reactive and neutralizing antibodies discovered by single-cell sequencing of plasma cells and mammalian display
RA Ehling, CR Weber, DM Mason, S Friedensohn, B Wagner, F Bieberich, ...
Cell reports 38 (3), 2022
20*2022
Reference-based comparison of adaptive immune receptor repertoires
CR Weber, T Rubio, L Wang, W Zhang, PA Robert, R Akbar, I Snapkov, ...
Cell Reports Methods 2 (8), 2022
112022
The physiological landscape and specificity of antibody repertoires
L Csepregi, KB Hoehn, D Neumeier, JM Taft, S Friedensohn, CR Weber, ...
bioRxiv, 2021.09. 15.460420, 2021
52021
Systems and methods to classify antibodies
D Mason, S Friedensohn, C Weber, S Reddy
US Patent App. 17/439,374, 2022
32022
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