Recent advances in 2D and 3D in vitro systems using primary hepatocytes, alternative hepatocyte sources and non-parenchymal liver cells and their use in investigating … P Godoy, NJ Hewitt, U Albrecht, ME Andersen, N Ansari, S Bhattacharya, ... Archives of toxicology 87, 1315-1530, 2013 | 1438 | 2013 |
Preparation and incubation of precision-cut liver and intestinal slices for application in drug metabolism and toxicity studies IAM De Graaf, P Olinga, MH De Jager, MT Merema, R De Kanter, ... Nature protocols 5 (9), 1540-1551, 2010 | 487 | 2010 |
Procalcitonin behaves as a fast responding acute phase proteinin vivoandin vitro MWN Nijsten, P Olinga, EGE de Vries, HS Koops, GMM Groothuis, ... Critical care medicine 28 (2), 458-461, 2000 | 465 | 2000 |
Targeting oxidative stress for the treatment of liver fibrosis T Luangmonkong, S Suriguga, HAM Mutsaers, GMM Groothuis, P Olinga, ... Reviews of Physiology, Biochemistry and Pharmacology, Vol. 175, 71-102, 2018 | 244 | 2018 |
LPS-induced downregulation of MRP2 and BSEP in human liver is due to a posttranscriptional process MGL Elferink, P Olinga, AL Draaisma, MT Merema, KN Faber, MJH Slooff, ... American Journal of Physiology-Gastrointestinal and Liver Physiology 287 (5 …, 2004 | 228 | 2004 |
Albumin Modified With Mannose 6–Phosphate: A Potential Carrier for Selective Delivery of Antifibrotic Drugs to Rat and Human Hepatic Stellate Cells L Beljaars, G Molema, B Weert, H Bonnema, P Olinga, GM Groothuis, ... Hepatology 29 (5), 1486-1493, 1999 | 225 | 1999 |
Precision-cut tissue slices as a tool to predict metabolism of novel drugs IAM Graaf, GMM Groothuis, P Olinga Expert opinion on drug metabolism & toxicology 3 (6), 879-898, 2007 | 186 | 2007 |
Targeting dexamethasone to Kupffer cells: effects on liver inflammation and fibrosis in rats BN Melgert, P Olinga, JMS Van Der Laan, B Weert, J Cho, D Schuppan, ... Hepatology 34 (4), 719-728, 2001 | 150 | 2001 |
Comparison of five incubation systems for rat liver slices using functional and viability parameters P Olinga, K Groen, IH Hof, R De Kanter, HJ Koster, WR Leeman, ... Journal of pharmacological and toxicological methods 38 (2), 59-69, 1997 | 140 | 1997 |
Precision-cut liver slices: a tool to model the liver ex vivo P Olinga, D Schuppan Journal of hepatology 58 (6), 1252-1253, 2013 | 138 | 2013 |
Liver slices in in vitro pharmacotoxicology with special reference to the use of human liver tissue P Olinga, DKF Meijer, MJH Slooff, GMM Groothuis Toxicology in vitro 12 (1), 77-100, 1997 | 125 | 1997 |
Rat liver slices as a tool to study LPS-induced inflammatory response in the liver P Olinga, MT Merema, MH De Jager, F Derks, BN Melgert, H Moshage, ... Journal of hepatology 35 (2), 187-194, 2001 | 124 | 2001 |
Liver fibrosis in vitro: cell culture models and precision-cut liver slices M Van de Bovenkamp, GMM Groothuis, DKF Meijer, P Olinga Toxicology in vitro 21 (4), 545-557, 2007 | 123 | 2007 |
Precision-cut liver slices as a new model to study toxicity-induced hepatic stellate cell activation in a physiologic milieu M Van de Bovenkamp, GMM Groothuis, AL Draaisma, MT Merema, ... Toxicological Sciences 85 (1), 632-638, 2005 | 122 | 2005 |
Microarray analysis in rat liver slices correctly predicts in vivo hepatotoxicity MGL Elferink, P Olinga, AL Draaisma, MT Merema, S Bauerschmidt, ... Toxicology and applied pharmacology 229 (3), 300-309, 2008 | 117 | 2008 |
Drug-metabolizing activity of human and rat liver, lung, kidney and intestine slices R De Kanter, MH De Jager, AL Draaisma, JU Jurva, P Olinga, DKF Meijer, ... Xenobiotica 32 (5), 349-362, 2002 | 114 | 2002 |
Coordinated induction of drug transporters and phase I and II metabolism in human liver slices P Olinga, MGL Elferink, AL Draaisma, MT Merema, JV Castell, G Perez, ... European journal of pharmaceutical sciences 33 (4-5), 380-389, 2008 | 113 | 2008 |
Prostaglandin E2 inhibits transforming growth factor β1-mediated induction of collagen α1 (I) in hepatic stellate cells AY Hui, AJ Dannenberg, JJY Sung, K Subbaramaiah, B Du, P Olinga, ... Journal of hepatology 41 (2), 251-258, 2004 | 113 | 2004 |
Novel biotransformation and physiological properties of norursodeoxycholic acid in humans AF Hofmann, SF Zakko, M Lira, C Clerici, LR Hagey, KK Lambert, ... Hepatology 42 (6), 1391-1398, 2005 | 111 | 2005 |
Effect of human liver source on the functionality of isolated hepatocytes and liver slices P Olinga, M Merema, IH Hof, KP de Jong, MJH Slooff, DKF Meijer, ... Drug Metabolism and Disposition 26 (1), 5-11, 1998 | 110 | 1998 |