Hilde Loge Nilsen
Hilde Loge Nilsen
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Guidelines for the use and interpretation of assays for monitoring autophagy (4th edition)1
DJ Klionsky, AK Abdel-Aziz, S Abdelfatah, M Abdellatif, A Abdoli, S Abel, ...
autophagy 17 (1), 1-382, 2021
Immunoglobulin isotype switching is inhibited and somatic hypermutation perturbed in UNG-deficient mice
C Rada, GT Williams, H Nilsen, DE Barnes, T Lindahl, MS Neuberger
Current Biology 12 (20), 1748-1755, 2002
Mitophagy inhibits amyloid-β and tau pathology and reverses cognitive deficits in models of Alzheimer’s disease
EF Fang, Y Hou, K Palikaras, BA Adriaanse, JS Kerr, B Yang, S Lautrup, ...
Nature neuroscience 22 (3), 401-412, 2019
Defective mitophagy in XPA via PARP-1 hyperactivation and NAD+/SIRT1 reduction
EF Fang, M Scheibye-Knudsen, LE Brace, H Kassahun, T SenGupta, ...
Cell 157 (4), 882-896, 2014
Base excision repair of DNA in mammalian cells
HE Krokan, H Nilsen, F Skorpen, M Otterlei, G Slupphaug
FEBS letters 476 (1-2), 73-77, 2000
Uracil-DNA glycosylase (UNG)-deficient mice reveal a primary role of the enzyme during DNA replication
H Nilsen, I Rosewell, P Robins, CF Skjelbred, S Andersen, G Slupphaug, ...
Molecular cell 5 (6), 1059-1065, 2000
Nuclear and mitochondrial uracil-DNA glycosylases are generated by alternative splicing and transcription from different positions in the UNG gene
H Nilsen, M Otterlei, T Haug, K Solum, TA Nagelhus, F Skorpen, ...
Nucleic acids research 25 (4), 750-755, 1997
hUNG2 is the major repair enzyme for removal of uracil from U: A matches, U: G mismatches, and U in single-stranded DNA, with hSMUG1 as a broad specificity backup
B Kavli, O Sundheim, M Akbari, M Otterlei, H Nilsen, F Skorpen, PA Aas, ...
Journal of Biological Chemistry 277 (42), 39926-39936, 2002
NAD+ Replenishment Improves Lifespan and Healthspan in Ataxia Telangiectasia Models via Mitophagy and DNA Repair
EF Fang, H Kassahun, DL Croteau, M Scheibye-Knudsen, K Marosi, H Lu, ...
Cell metabolism 24 (4), 566-581, 2016
Base excision repair in a network of defence and tolerance
H Nilsen, HE Krokan
Carcinogenesis 22 (7), 987-998, 2001
Mitophagy in neurodegeneration and aging
EM Fivenson, S Lautrup, N Sun, M Scheibye-Knudsen, T Stevnsner, ...
Neurochemistry international 109, 202-209, 2017
Excision of deaminated cytosine from the vertebrate genome: role of the SMUG1 uracil–DNA glycosylase
H Nilsen, KA Haushalter, P Robins, DE Barnes, GL Verdine, T Lindahl
The EMBO journal 20 (15), 4278-4286, 2001
Gene-targeted mice lacking the Ung uracil-DNA glycosylase develop B-cell lymphomas
H Nilsen, G Stamp, S Andersen, G Hrivnak, HE Krokan, T Lindahl, ...
Oncogene 22 (35), 5381-5386, 2003
Incorporation of dUMP into DNA is a major source of spontaneous DNA damage, while excision of uracil is not required for cytotoxicity of fluoropyrimidines in mouse embryonic …
S Andersen, T Heine, R Sneve, I König, HE Krokan, B Epe, H Nilsen
Carcinogenesis 26 (3), 547-555, 2005
DNA base excision repair of uracil residues in reconstituted nucleosome core particles
H Nilsen, T Lindahl, A Verreault
The EMBO journal 21 (21), 5943-5952, 2002
NAD+ augmentation restores mitophagy and limits accelerated aging in Werner syndrome
EF Fang, Y Hou, S Lautrup, MB Jensen, B Yang, T SenGupta, D Caponio, ...
Nature communications 10 (1), 1-18, 2019
Tomatidine enhances lifespan and healthspan in C. elegans through mitophagy induction via the SKN-1/Nrf2 pathway
EF Fang, TB Waltz, H Kassahun, Q Lu, JS Kerr, M Morevati, EM Fivenson, ...
Scientific reports 7 (1), 1-13, 2017
Properties and functions of human uracil-DNA glycosylase from the UNG gene
HE Krokan, M Otterlei, H Nilsen, B Kavli, F Skorpen, S Andersen, ...
Progress in nucleic acid research and molecular biology 68, 365-386, 2001
Abrogation of the CLK‐2 checkpoint leads to tolerance to base‐excision repair intermediates
M Dengg, T Garcia‐Muse, SG Gill, N Ashcroft, SJ Boulton, H Nilsen
EMBO reports 7 (10), 1046-1051, 2006
Cockayne syndrome group A and B proteins converge on transcription-linked resolution of non-B DNA
M Scheibye-Knudsen, A Tseng, M Borch Jensen, K Scheibye-Alsing, ...
Proceedings of the National Academy of Sciences 113 (44), 12502-12507, 2016
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