Amit Singh
Amit Singh
Associate Professor, IISc
Verified email at - Homepage
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Mycobacterium tuberculosis WhiB3 Maintains Redox Homeostasis by Regulating Virulence Lipid Anabolism to Modulate Macrophage Response
A Singh, DK Crossman, D Mai, L Guidry, MI Voskuil, MB Renfrow, ...
PLoS pathogens 5 (8), e1000545, 2009
Mycobacterium tuberculosis WhiB3 responds to O2 and nitric oxide via its [4Fe-4S] cluster and is essential for nutrient starvation survival
A Singh, L Guidry, KV Narasimhulu, D Mai, J Trombley, KE Redding, ...
Proceedings of the National Academy of Sciences 104 (28), 11562-11567, 2007
Reengineering Redox Sensitive GFP to Measure Mycothiol Redox Potential of Mycobacterium tuberculosis during Infection
A Bhaskar, M Chawla, M Mehta, P Parikh, P Chandra, D Bhave, D Kumar, ...
PLoS pathogens 10 (1), e1003902, 2014
Disruption of mptpB impairs the ability of Mycobacterium tuberculosis to survive in guinea pigs
R Singh, V Rao, H Shakila, R Gupta, A Khera, N Dhar, A Singh, A Koul, ...
Molecular microbiology 50 (3), 751-762, 2003
Dissecting virulence pathways of Mycobacterium tuberculosis through protein–protein association
A Singh, D Mai, A Kumar, AJC Steyn
Proceedings of the National Academy of Sciences 103 (30), 11346-11351, 2006
Mycobacterium tuberculosis inhibits RAB7 recruitment to selectively modulate autophagy flux in macrophages
P Chandra, S Ghanwat, SK Matta, SS Yadav, M Mehta, Z Siddiqui, ...
Scientific reports 5 (1), 1-10, 2015
Requirement of the mymA Operon for Appropriate Cell Wall Ultrastructure and Persistence of Mycobacterium tuberculosis in the Spleens of Guinea Pigs
A Singh, R Gupta, RA Vishwakarma, PR Narayanan, CN Paramasivan, ...
Journal of bacteriology 187 (12), 4173-4186, 2005
Role of Mycobacterium tuberculosis Ser/Thr Kinase PknF: Implications in Glucose Transport and Cell Division
P Deol, R Vohra, AK Saini, A Singh, H Chandra, P Chopra, TK Das, ...
Journal of bacteriology 187 (10), 3415-3420, 2005
Mycobacterium tuberculosis WhiB4 regulates oxidative stress response to modulate survival and dissemination in vivo
M Chawla, P Parikh, A Saxena, MH Munshi, M Mehta, D Mai, ...
Molecular microbiology 85 (6), 1148-1165, 2012
mymA operon of Mycobacterium tuberculosis: its regulation and importance in the cell envelope
A Singh, S Jain, S Gupta, T Das, AK Tyagi
FEMS Microbiology Letters 227 (1), 53-63, 2003
Mycobacterium tuberculosis WhiB3 responds to vacuolar pH-induced changes in mycothiol redox potential to modulate phagosomal maturation and virulence
M Mehta, RS Rajmani, A Singh
Journal of Biological Chemistry 291 (6), 2888-2903, 2016
Hydrogen sulfide in physiology and pathogenesis of bacteria and viruses
VK Pal, P Bandyopadhyay, A Singh
IUBMB life 70 (5), 393-410, 2018
Protein kinase G confers survival advantage to Mycobacterium tuberculosis during latency-like conditions
MZ Khan, A Bhaskar, S Upadhyay, P Kumari, RS Rajmani, P Jain, ...
Journal of Biological Chemistry 292 (39), 16093-16108, 2017
Targeting redox heterogeneity to counteract drug tolerance in replicating Mycobacterium tuberculosis
R Mishra, S Kohli, N Malhotra, P Bandyopadhyay, M Mehta, MH Munshi, ...
Science translational medicine 11 (518), eaaw6635, 2019
Mycobacterium tuberculosis has diminished capacity to counteract redox stress induced by elevated levels of endogenous superoxide
P Tyagi, AT Dharmaraja, A Bhaskar, H Chakrapani, A Singh
Free Radical Biology and Medicine 84, 344-354, 2015
Reductive stress in microbes: implications for understanding Mycobacterium tuberculosis disease and persistence
A Farhana, L Guidry, A Srivastava, A Singh, MK Hondalus, AJC Steyn
Advances in microbial physiology 57, 43-117, 2010
Measuring glutathione redox potential of HIV-1-infected macrophages
A Bhaskar, MH Munshi, SZ Khan, S Fatima, R Arya, S Jameel, A Singh
Journal of Biological Chemistry 290 (2), 1020-1038, 2015
Efficacy of β-lactam/β-lactamase inhibitor combination is linked to WhiB4-mediated changes in redox physiology of Mycobacterium tuberculosis
S Mishra, P Shukla, A Bhaskar, K Anand, P Baloni, RK Jha, A Mohan, ...
Elife 6, e25624, 2017
Mycobacterium tuberculosis WhiB3 maintains redox homeostasis and survival in response to reactive oxygen and nitrogen species
M Mehta, A Singh
Free Radical Biology and Medicine 131, 50-58, 2019
Meta-analysis of host response networks identifies a common core in tuberculosis
A Sambarey, A Devaprasad, P Baloni, M Mishra, A Mohan, P Tyagi, ...
NPJ systems biology and applications 3 (1), 4, 2017
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