| The epichaperome is an integrated chaperome network that facilitates tumour survival A Rodina, T Wang, P Yan, EDG Gomes, MPS Dunphy, N Pillarsetty, ... Nature 538 (7625), 397-401, 2016 | 247 | 2016 |
| Adapting to stress—chaperome networks in cancer S Joshi, T Wang, TLS Araujo, S Sharma, JL Brodsky, G Chiosis Nature Reviews Cancer 18 (9), 562-575, 2018 | 110 | 2018 |
| Gold/alpha-lactalbumin nanoprobes for the imaging and treatment of breast cancer J Yang, T Wang, L Zhao, VK Rajasekhar, S Joshi, C Andreou, S Pal, ... Nature biomedical engineering 4 (7), 686-703, 2020 | 66 | 2020 |
| The epichaperome is a mediator of toxic hippocampal stress and leads to protein connectivity-based dysfunction MC Inda, S Joshi, T Wang, A Bolaender, S Gandu, J Koren III, AY Che, ... Nature Communications 11 (1), 319, 2020 | 50 | 2020 |
| Differences in Conformational Dynamics between Plasmodium falciparum and Human Hsp90 Orthologues Enable the Structure-Based Discovery of Pathogen … T Wang, WH Bisson, P Mäser, L Scapozza, D Picard Journal of medicinal chemistry 57 (6), 2524-2535, 2014 | 48 | 2014 |
| Paradigms for precision medicine in epichaperome cancer therapy N Pillarsetty, K Jhaveri, T Taldone, E Caldas-Lopes, B Punzalan, S Joshi, ... Cancer Cell 36 (5), 559-573. e7, 2019 | 45 | 2019 |
| HSP90-incorporating chaperome networks as biosensor for disease-related pathways in patient-specific midbrain dopamine neurons S Kishinevsky, T Wang, A Rodina, SY Chung, C Xu, J Philip, T Taldone, ... Nature communications 9 (1), 4345, 2018 | 43 | 2018 |
| Inhibition of Plasmodium falciparum Hsp90 Contributes to the Antimalarial Activities of Aminoalcohol-carbazoles T Wang, P Mäser, D Picard Journal of Medicinal Chemistry 59 (13), 6344-6352, 2016 | 43 | 2016 |
| Chaperome heterogeneity and its implications for cancer study and treatment T Wang, A Rodina, MP Dunphy, A Corben, S Modi, ML Guzman, ... Journal of Biological Chemistry 294 (6), 2162-2179, 2019 | 42 | 2019 |
| Molecular stressors engender protein connectivity dysfunction through aberrant N-glycosylation of a chaperone P Yan, HJ Patel, S Sharma, A Corben, T Wang, P Panchal, C Yang, ... Cell reports 31 (13), 2020 | 39 | 2020 |
| A chemical biology approach to the chaperome in cancer—HSP90 and beyond T Taldone, T Wang, A Rodina, NVK Pillarsetty, CS Digwal, S Sharma, ... Cold Spring Harbor perspectives in biology 12 (4), a034116, 2020 | 36 | 2020 |
| The sensitivity to Hsp90 inhibitors of both normal and oncogenically transformed cells is determined by the equilibrium between cellular quiescence and activity PC Echeverria, K Bhattacharya, A Joshi, T Wang, D Picard PLoS One 14 (2), e0208287, 2019 | 26 | 2019 |
| Proteomic interrogation of HSP90 and insights for medical research L Weidenauer, T Wang, S Joshi, G Chiosis, MR Quadroni Expert review of proteomics 14 (12), 1105-1117, 2017 | 22 | 2017 |
| Chaperome networks–redundancy and implications for cancer treatment P Yan, T Wang, ML Guzman, RI Peter, G Chiosis HSF1 and Molecular Chaperones in Biology and Cancer, 87-99, 2020 | 18 | 2020 |
| Disease‐specific interactome alterations via epichaperomics: the case for Alzheimer’s disease SD Ginsberg, TA Neubert, S Sharma, CS Digwal, P Yan, C Timbus, ... The FEBS journal 289 (8), 2047-2066, 2022 | 17 | 2022 |
| Stressing out Hsp90 in neurotoxic proteinopathies C Inda, A Bolaender, T Wang, S R Gandu, J Koren III Current topics in medicinal chemistry 16 (25), 2829-2838, 2016 | 17 | 2016 |
| The penalty of stress‐Epichaperomes negatively reshaping the brain in neurodegenerative disorders SD Ginsberg, S Joshi, S Sharma, G Guzman, T Wang, O Arancio, ... Journal of neurochemistry 159 (6), 958-979, 2021 | 14 | 2021 |
| Long-lasting and fast-acting in vivo efficacious antiplasmodial azepanylcarbazole amino alcohol N Abla, S Bashyam, SA Charman, B Greco, P Hewitt, MB Jiménez-Díaz, ... ACS medicinal chemistry letters 8 (12), 1304-1308, 2017 | 14 | 2017 |
| Pharmacologically controlling protein-protein interactions through epichaperomes for therapeutic vulnerability in cancer S Joshi, EDG Gomes, T Wang, A Corben, T Taldone, S Gandu, C Xu, ... Communications Biology 4 (1), 1333, 2021 | 12 | 2021 |
| Systems-level analyses of protein-protein interaction network dysfunctions via epichaperomics identify cancer-specific mechanisms of stress adaptation A Rodina, C Xu, CS Digwal, S Joshi, Y Patel, AR Santhaseela, S Bay, ... Nature communications 14 (1), 3742, 2023 | 8 | 2023 |
Gabriela ChiosisProfessor, Memorial Sloan KetteringVerified email at mskcc.org
