BET domain co-regulators in obesity, inflammation and cancer AC Belkina, GV Denis Nature reviews Cancer 12 (7), 465-477, 2012 | 777 | 2012 |
B cells promote inflammation in obesity and type 2 diabetes through regulation of T-cell function and an inflammatory cytokine profile J DeFuria, AC Belkina, M Jagannathan-Bogdan, J Snyder-Cappione, ... Proceedings of the National Academy of Sciences 110 (13), 5133-5138, 2013 | 590 | 2013 |
BET protein function is required for inflammation: Brd2 genetic disruption and BET inhibitor JQ1 impair mouse macrophage inflammatory responses AC Belkina, BS Nikolajczyk, GV Denis The Journal of Immunology 190 (7), 3670-3678, 2013 | 449 | 2013 |
BET bromodomain inhibition as a novel strategy for reactivation of HIV-1 C Banerjee, N Archin, D Michaels, AC Belkina, GV Denis, J Bradner, ... Journal of leukocyte biology 92 (6), 1147-1154, 2012 | 351 | 2012 |
Brd2 disruption in mice causes severe obesity without Type 2 diabetes F Wang, H Liu, WP Blanton, A Belkina, NK Lebrasseur, GV Denis Biochemical Journal 425 (1), 71-85, 2010 | 273 | 2010 |
Clinical trials for BET inhibitors run ahead of the science G Andrieu, AC Belkina, GV Denis Drug Discovery Today: Technologies 19, 45-50, 2016 | 271 | 2016 |
‘Metabolically healthy obesity’: origins and implications GV Denis, MS Obin Molecular aspects of medicine 34 (1), 59-70, 2013 | 251 | 2013 |
RING3 kinase transactivates promoters of cell cycle regulatory genes through E2F GV Denis, C Vaziri, N Guo, DV Faller | 214 | 2000 |
Kaposi's sarcoma-associated herpesvirus latency-associated nuclear antigen interacts with bromodomain protein Brd4 on host mitotic chromosomes J You, V Srinivasan, GV Denis, WJ Harrington Jr, ME Ballestas, KM Kaye, ... Journal of virology 80 (18), 8909-8919, 2006 | 210 | 2006 |
A novel, mitogen-activated nuclear kinase is related to a Drosophila developmental regulator. GV Denis, MR Green Genes & development 10 (3), 261-271, 1996 | 186 | 1996 |
Identification of transcription complexes that contain the double bromodomain protein Brd2 and chromatin remodeling machines GV Denis, ME McComb, DV Faller, A Sinha, PB Romesser, CE Costello Journal of proteome research 5 (3), 502-511, 2006 | 184 | 2006 |
Eμ-BRD2 transgenic mice develop B-cell lymphoma and leukemia RJ Greenwald, JR Tumang, A Sinha, N Currier, RD Cardiff, TL Rothstein, ... Blood 103 (4), 1475-1484, 2004 | 173 | 2004 |
Bromodomain analysis of Brd2-dependent transcriptional activation of cyclin A A Sinha, DV Faller, GV Denis Biochemical Journal 387 (1), 257-269, 2005 | 143 | 2005 |
BRD4 regulates breast cancer dissemination through Jagged1/Notch1 signaling G Andrieu, AH Tran, KJ Strissel, GV Denis Cancer research 76 (22), 6555-6567, 2016 | 134 | 2016 |
Metabolic disease risk in children by salivary biomarker analysis JM Goodson, A Kantarci, ML Hartman, GV Denis, D Stephens, H Hasturk, ... PloS one 9 (6), e98799, 2014 | 133 | 2014 |
Bromodomain coactivators in cancer, obesity, type 2 diabetes, and inflammation GV Denis Discovery medicine 10 (55), 489, 2010 | 131 | 2010 |
Protein arginine methyltransferase 5 (PRMT5) inhibition induces lymphoma cell death through reactivation of the retinoblastoma tumor suppressor pathway and polycomb repressor … J Chung, V Karkhanis, S Tae, F Yan, P Smith, LW Ayers, C Agostinelli, ... Journal of Biological Chemistry 288 (49), 35534-35547, 2013 | 130 | 2013 |
Metabolic health reduces risk of obesity-related cancer in framingham study adults LL Moore, S Chadid, MR Singer, BE Kreger, GV Denis Cancer Epidemiology, Biomarkers & Prevention 23 (10), 2057-2065, 2014 | 110 | 2014 |
Obesity genes and insulin resistance AC Belkina, GV Denis Current Opinion in Endocrinology, Diabetes and Obesity 17 (5), 472-477, 2010 | 104 | 2010 |
BET bromodomain proteins Brd2, Brd3 and Brd4 selectively regulate metabolic pathways in the pancreatic β-cell JT Deeney, AC Belkina, OS Shirihai, BE Corkey, GV Denis PloS one 11 (3), e0151329, 2016 | 84 | 2016 |