Broad neutralization coverage of HIV by multiple highly potent antibodies LM Walker, M Huber, KJ Doores, E Falkowska, R Pejchal, JP Julien, ... Nature 477 (7365), 466-470, 2011 | 1771 | 2011 |
Structure of HIV-1 gp120 V1/V2 domain with broadly neutralizing antibody PG9 JS McLellan, M Pancera, C Carrico, J Gorman, JP Julien, R Khayat, ... Nature 480 (7377), 336-343, 2011 | 1058 | 2011 |
A next-generation cleaved, soluble HIV-1 Env trimer, BG505 SOSIP. 664 gp140, expresses multiple epitopes for broadly neutralizing but not non-neutralizing antibodies RW Sanders, R Derking, A Cupo, JP Julien, A Yasmeen, N de Val, HJ Kim, ... PLoS pathog 9 (9), e1003618, 2013 | 1025 | 2013 |
Crystal structure of a soluble cleaved HIV-1 envelope trimer JP Julien, A Cupo, D Sok, RL Stanfield, D Lyumkis, MC Deller, PJ Klasse, ... Science 342 (6165), 1477-1483, 2013 | 974 | 2013 |
A potent and broad neutralizing antibody recognizes and penetrates the HIV glycan shield R Pejchal, KJ Doores, LM Walker, R Khayat, PS Huang, SK Wang, ... Science 334 (6059), 1097-1103, 2011 | 886 | 2011 |
Rational HIV immunogen design to target specific germline B cell receptors J Jardine, JP Julien, S Menis, T Ota, O Kalyuzhniy, A McGuire, D Sok, ... Science 340 (6133), 711-716, 2013 | 838 | 2013 |
Cryo-EM structure of a fully glycosylated soluble cleaved HIV-1 envelope trimer D Lyumkis, JP Julien, N de Val, A Cupo, CS Potter, PJ Klasse, DR Burton, ... Science 342 (6165), 1484-1490, 2013 | 806 | 2013 |
HIV-1 neutralizing antibodies induced by native-like envelope trimers RW Sanders, MJ van Gils, R Derking, D Sok, TJ Ketas, JA Burger, ... Science 349 (6244), aac4223, 2015 | 561 | 2015 |
HIV-1 broadly neutralizing antibody precursor B cells revealed by germline-targeting immunogen JG Jardine, DW Kulp, C Havenar-Daughton, A Sarkar, B Briney, D Sok, ... Science 351 (6280), 1458-1463, 2016 | 457 | 2016 |
Supersite of immune vulnerability on the glycosylated face of HIV-1 envelope glycoprotein gp120 L Kong, JH Lee, KJ Doores, CD Murin, JP Julien, R McBride, Y Liu, ... Nature Structural and Molecular Biology 20 (7), 796, 2013 | 418 | 2013 |
Broadly neutralizing antibody PGT121 allosterically modulates CD4 binding via recognition of the HIV-1 gp120 V3 base and multiple surrounding glycans JP Julien, D Sok, R Khayat, JH Lee, KJ Doores, LM Walker, A Ramos, ... PLoS Pathog 9 (5), e1003342, 2013 | 414 | 2013 |
Structural delineation of a quaternary, cleavage-dependent epitope at the gp41-gp120 interface on intact HIV-1 Env trimers C Blattner, JH Lee, K Sliepen, R Derking, E Falkowska, AT de la Pena, ... Immunity 40 (5), 669-680, 2014 | 405 | 2014 |
Recombinant HIV envelope trimer selects for quaternary-dependent antibodies targeting the trimer apex D Sok, MJ van Gils, M Pauthner, JP Julien, KL Saye-Francisco, J Hsueh, ... Proceedings of the National Academy of Sciences 111 (49), 17624-17629, 2014 | 387 | 2014 |
Immunogenicity of Stabilized HIV-1 Envelope Trimers with Reduced Exposure of Non-neutralizing Epitopes SW de Taeye, G Ozorowski, AT de la Peņa, M Guttman, JP Julien, ... Cell 163 (7), 1702-1715, 2015 | 357 | 2015 |
Asymmetric recognition of the HIV-1 trimer by broadly neutralizing antibody PG9 JP Julien, JH Lee, A Cupo, CD Murin, R Derking, S Hoffenberg, ... Proceedings of the National Academy of Sciences 110 (11), 4351-4356, 2013 | 311 | 2013 |
A Native-Like SOSIP. 664 Trimer Based on an HIV-1 Subtype B env Gene P Pugach, G Ozorowski, A Cupo, R Ringe, A Yasmeen, N de Val, ... Journal of virology 89 (6), 3380-3395, 2015 | 279 | 2015 |
The effects of somatic hypermutation on neutralization and binding in the PGT121 family of broadly neutralizing HIV antibodies D Sok, U Laserson, J Laserson, Y Liu, F Vigneault, JP Julien, B Briney, ... PLoS pathog 9 (11), e1003754, 2013 | 253 | 2013 |
A Broadly Neutralizing Antibody Targets the Dynamic HIV Envelope Trimer Apex via a Long, Rigidified, and Anionic β-Hairpin Structure JH Lee, R Andrabi, CY Su, A Yasmeen, JP Julien, L Kong, NC Wu, ... Immunity 46 (4), 690-702, 2017 | 250 | 2017 |
The structural basis of modified nucleosome recognition by 53BP1 MD Wilson, S Benlekbir, A Fradet-Turcotte, A Sherker, JP Julien, ... Nature 536 (7614), 100-103, 2016 | 250 | 2016 |
Structural evolution of glycan recognition by a family of potent HIV antibodies F Garces, D Sok, L Kong, R McBride, HJ Kim, KF Saye-Francisco, ... Cell 159 (1), 69-79, 2014 | 242 | 2014 |