| Overactivated neddylation pathway as a therapeutic target in lung cancer L Li, M Wang, G Yu, P Chen, H Li, D Wei, J Zhu, L Xie, H Jia, J Shi, C Li, ... Journal of the National Cancer Institute 106 (6), dju083, 2014 | 184 | 2014 |
| Neddylation inhibition activates the extrinsic apoptosis pathway through ATF4–CHOP–DR5 axis in human esophageal cancer cells P Chen, T Hu, Y Liang, P Li, X Chen, J Zhang, Y Ma, Q Hao, J Wang, ... Clinical cancer research 22 (16), 4145-4157, 2016 | 110 | 2016 |
| Suppression of tumor angiogenesis by targeting the protein neddylation pathway WT Yao, JF Wu, GY Yu, R Wang, K Wang, LH Li, P Chen, YN Jiang, ... Cell death & disease 5 (2), e1059-e1059, 2014 | 86 | 2014 |
| PPARγ neddylation essential for adipogenesis is a potential target for treating obesity HS Park, UI Ju, JW Park, JY Song, DH Shin, KH Lee, LS Jeong, J Yu, ... Cell death & differentiation 23 (8), 1296-1311, 2016 | 79 | 2016 |
| Selenoacyclovir and selenoganciclovir: Discovery of a new template for antiviral agents PK Sahu, T Umme, J Yu, A Nayak, G Kim, M Noh, JY Lee, DD Kim, ... Journal of Medicinal Chemistry 58 (21), 8734-8738, 2015 | 67 | 2015 |
| Promotion of tumor-associated macrophages infiltration by elevated neddylation pathway via NF-κB-CCL2 signaling in lung cancer L Zhou, Y Jiang, X Liu, L Li, X Yang, C Dong, X Liu, Y Lin, Y Li, J Yu, R He, ... Oncogene 38 (29), 5792-5804, 2019 | 64 | 2019 |
| Stereoselective synthesis of 4′-selenonucleosides via seleno-Michael reaction as potent antiviral agents PK Sahu, G Kim, J Yu, JY Ahn, J Song, Y Choi, X Jin, JH Kim, SK Lee, ... Organic letters 16 (21), 5796-5799, 2014 | 48 | 2014 |
| Neddylation pathway regulates the proliferation and survival of macrophages L Li, B Liu, T Dong, HW Lee, J Yu, Y Zheng, H Gao, Y Zhang, Y Chu, G Liu, ... Biochemical and Biophysical Research Communications 432 (3), 494-498, 2013 | 47 | 2013 |
| New RNA Purine Building Blocks, 4′-Selenopurine Nucleosides: First Synthesis and Unusual Mixture of Sugar Puckerings. J Yu, JH Kim, HW Lee, V Alexander, HC Ahn, WJ Choi, J Choi, LS Jeong Chemistry-A European Journal 19 (18), 2013 | 44 | 2013 |
| Structure-Guided Modification of Heterocyclic Antagonists of the P2Y14 Receptor J Yu, A Ciancetta, S Dudas, S Duca, J Lottermoser, KA Jacobson Journal of medicinal chemistry 61 (11), 4860-4882, 2018 | 42 | 2018 |
| Neddylation inactivation facilitates FOXO3a nuclear export to suppress estrogen receptor transcription and improve fulvestrant sensitivity X Jia, C Li, L Li, X Liu, L Zhou, W Zhang, S Ni, Y Lu, L Chen, LS Jeong, ... Clinical Cancer Research 25 (12), 3658-3672, 2019 | 39 | 2019 |
| A novel selenonucleoside suppresses tumor growth by targeting Skp2 degradation in paclitaxel-resistant prostate cancer WS Byun, M Jin, J Yu, WK Kim, J Song, HJ Chung, LS Jeong, SK Lee Biochemical Pharmacology 158, 84-94, 2018 | 38 | 2018 |
| Design, synthesis and anticancer activity of fluorocyclopentenyl-purines and–pyrimidines J Yoon, DB Jarhad, G Kim, A Nayak, LX Zhao, J Yu, HR Kim, JY Lee, ... European Journal of Medicinal Chemistry 155, 406-417, 2018 | 38 | 2018 |
| Radiosensitization by the investigational NEDD8-activating enzyme inhibitor MLN4924 (pevonedistat) in hormone-resistant prostate cancer cells X Wang, W Zhang, Z Yan, Y Liang, L Li, X Yu, Y Feng, S Fu, Y Zhang, ... Oncotarget 7 (25), 38380, 2016 | 34 | 2016 |
| Polypharmacology of N6-(3-Iodobenzyl)adenosine-5′-N-methyluronamide (IB-MECA) and Related A3 Adenosine Receptor Ligands: Peroxisome Proliferator … J Yu, S Ahn, HJ Kim, M Lee, S Ahn, J Kim, SH Jin, E Lee, G Kim, ... Journal of medicinal chemistry 60 (17), 7459-7475, 2017 | 33 | 2017 |
| Structure–activity relationships of 2′-modified-4′-selenoarabinofuranosyl-pyrimidines as anticancer agents JH Kim, J Yu, V Alexander, JH Choi, J Song, HW Lee, HO Kim, J Choi, ... European Journal of Medicinal Chemistry 83, 208-225, 2014 | 27 | 2014 |
| UBC12‐mediated SREBP‐1 neddylation worsens metastatic tumor prognosis MJ Heo, SH Kang, YS Kim, JM Lee, J Yu, HR Kim, H Lim, KM Kim, J Jung, ... International Journal of Cancer 147 (9), 2550-2563, 2020 | 26 | 2020 |
| Anticancer effects of propionic acid inducing cell death in cervical cancer cells CH Pham, JE Lee, J Yu, SH Lee, KR Yu, J Hong, N Cho, S Kim, D Kang, ... Molecules 26 (16), 4951, 2021 | 25 | 2021 |
| P2Y14 Receptor Antagonists Reverse Chronic Neuropathic Pain in a Mouse Model F Mufti, YH Jung, LA Giancotti, J Yu, Z Chen, NB Phung, KA Jacobson, ... ACS Medicinal Chemistry Letters 11 (6), 1281-1286, 2020 | 25 | 2020 |
| The Nedd8‐activating enzyme inhibitor MLN 4924 (TAK‐924/Pevonedistat) induces apoptosis via c‐Myc‐Noxa axis in head and neck squamous cell carcinoma W Zhang, Y Liang, L Li, X Wang, Z Yan, C Dong, MS Zeng, Q Zhong, ... Cell Proliferation 52 (2), e12536, 2019 | 25 | 2019 |
