| HIV vaccine design to target germline precursors of glycan-dependent broadly neutralizing antibodies JM Steichen, DW Kulp, T Tokatlian, A Escolano, P Dosenovic, ... Immunity 45 (3), 483-496, 2016 | 395 | 2016 |
| Structural evolution of glycan recognition by a family of potent HIV antibodies F Garces, D Sok, L Kong, R McBride, HJ Kim, KF Saye-Francisco, ... Cell 159 (1), 69-79, 2014 | 240 | 2014 |
| Affinity maturation of a potent family of HIV antibodies is primarily focused on accommodating or avoiding glycans F Garces, JH Lee, N de Val, AT de la Pena, L Kong, C Puchades, Y Hua, ... Immunity 43 (6), 1053-1063, 2015 | 224 | 2015 |
| Design and crystal structure of a native-like HIV-1 envelope trimer that engages multiple broadly neutralizing antibody precursors in vivo M Medina-Ramírez, F Garces, A Escolano, P Skog, SW de Taeye, ... Journal of Experimental Medicine 214 (9), 2573-2590, 2017 | 168 | 2017 |
| Improving the immunogenicity of native-like HIV-1 envelope trimers by hyperstabilization AT de la Pena, JP Julien, SW de Taeye, F Garces, M Guttman, ... Cell reports 20 (8), 1805-1817, 2017 | 157 | 2017 |
| Early antibody lineage diversification and independent limb maturation lead to broad HIV-1 neutralization targeting the Env high-mannose patch DT MacLeod, NM Choi, B Briney, F Garces, LS Ver, E Landais, B Murrell, ... Immunity 44 (5), 1215-1226, 2016 | 139 | 2016 |
| Structure and immunogenicity of a stabilized HIV-1 envelope trimer based on a group-M consensus sequence K Sliepen, BW Han, I Bontjer, P Mooij, F Garces, AJ Behrens, ... Nature communications 10 (1), 2355, 2019 | 138 | 2019 |
| Two classes of broadly neutralizing antibodies within a single lineage directed to the high-mannose patch of HIV envelope KJ Doores, L Kong, SA Krumm, KM Le, D Sok, U Laserson, F Garces, ... Journal of virology 89 (2), 1105-1118, 2015 | 103 | 2015 |
| Structural flexibility at a major conserved antibody target on hepatitis C virus E2 antigen L Kong, DE Lee, RU Kadam, T Liu, E Giang, T Nieusma, F Garces, ... Proceedings of the National Academy of Sciences 113 (45), 12768-12773, 2016 | 89 | 2016 |
| Key gp120 glycans pose roadblocks to the rapid development of VRC01-class antibodies in an HIV-1-infected Chinese donor L Kong, B Ju, Y Chen, L He, L Ren, J Liu, K Hong, B Su, Z Wang, ... Immunity 44 (4), 939-950, 2016 | 86 | 2016 |
| Glycine substitution at helix-to-coil transitions facilitates the structural determination of a stabilized subtype C HIV envelope glycoprotein J Guenaga, F Garces, N de Val, RL Stanfield, V Dubrovskaya, B Higgins, ... Immunity 46 (5), 792-803. e3, 2017 | 85 | 2017 |
| Efficient single-strand break repair requires binding to both poly (ADP-ribose) and DNA by the central BRCT domain of XRCC1 LM Polo, Y Xu, P Hornyak, F Garces, Z Zeng, R Hailstone, SJ Matthews, ... Cell reports 26 (3), 573-581. e5, 2019 | 82 | 2019 |
| Elicitation of neutralizing antibodies targeting the V2 apex of the HIV envelope trimer in a wild-type animal model JE Voss, R Andrabi, LE McCoy, N de Val, RP Fuller, T Messmer, CY Su, ... Cell reports 21 (1), 222-235, 2017 | 71 | 2017 |
| Complete epitopes for vaccine design derived from a crystal structure of the broadly neutralizing antibodies PGT128 and 8ANC195 in complex with an HIV-1 Env trimer L Kong, A Torrents de la Peña, MC Deller, F Garces, K Sliepen, Y Hua, ... Acta Crystallographica Section D: Biological Crystallography 71 (10), 2099-2108, 2015 | 69 | 2015 |
| Enhancing the prefusion conformational stability of SARS-CoV-2 spike protein through structure-guided design TP Riley, HT Chou, R Hu, KP Bzymek, AR Correia, AC Partin, D Li, ... Frontiers in immunology 12, 660198, 2021 | 43 | 2021 |
| The structural basis for substrate recognition by mammalian polynucleotide kinase 3′ phosphatase F Garces, LH Pearl, AW Oliver Molecular cell 44 (3), 385-396, 2011 | 43 | 2011 |
| Molecular insight into recognition of the CGRPR complex by migraine prevention therapy Aimovig (Erenumab) F Garces, C Mohr, LI Zhang, CS Huang, Q Chen, C King, C Xu, Z Wang Cell Reports 30 (6), 1714-1723. e6, 2020 | 42 | 2020 |
| Quaternary Structural Transitions in the DeoR-Type Repressor UlaR Control Transcriptional Readout from the l-Ascorbate Utilization Regulon in Escherichia coli F Garces, FJ Fernández, AM Gómez, R Pérez-Luque, E Campos, ... Biochemistry 47 (44), 11424-11433, 2008 | 37 | 2008 |
| The chimpanzee SIV envelope trimer: structure and deployment as an HIV vaccine template R Andrabi, J Pallesen, JD Allen, G Song, J Zhang, N de Val, G Gegg, ... Cell reports 27 (8), 2426-2441. e6, 2019 | 36 | 2019 |
| Aerobic L-ascorbate metabolism and associated oxidative stress in Escherichia coli E Campos, C Montella, F Garces, L Baldoma, J Aguilar, J Badia Microbiology 153 (10), 3399-3408, 2007 | 36 | 2007 |
Leopold KongThe U.S. Food and Drug AdministrationVerified email at fda.hhs.gov
