Stereochemical requirements for β-hairpin formation: model studies with four-residue peptides and depsipeptides TS Haque, JC Little, SH Gellman Journal of the American Chemical Society 118 (29), 6975-6985, 1996 | 318 | 1996 |
Insights on β-hairpin stability in aqueous solution from peptides with enforced type i ‘and type ii ‘β-turns TS Haque, SH Gellman Journal of the American Chemical Society 119 (9), 2303-2304, 1997 | 306 | 1997 |
Potent, low-molecular-weight non-peptide inhibitors of malarial aspartyl protease plasmepsin II TS Haque, AG Skillman, CE Lee, H Habashita, IY Gluzman, TJA Ewing, ... Journal of Medicinal Chemistry 42 (8), 1428-1440, 1999 | 223 | 1999 |
Novel uncomplexed and complexed structures of plasmepsin II, an aspartic protease from Plasmodium falciparum OA Asojo, SV Gulnik, E Afonina, B Yu, JA Ellman, TS Haque, AM Silva Journal of molecular biology 327 (1), 173-181, 2003 | 161 | 2003 |
" Mirror image" reverse turns promote. beta.-hairpin formation TS Haque, JC Little, SH Gellman Journal of the American Chemical Society 116 (9), 4105-4106, 1994 | 149 | 1994 |
Novel cathepsin D inhibitors block the formation of hyperphosphorylated tau fragments in hippocampus X Bi, TS Haque, J Zhou, AG Skillman, B Lin, CE Lee, ID Kuntz, JA Ellman, ... Journal of neurochemistry 74 (4), 1469-1477, 2000 | 99 | 2000 |
Parallel Synthesis of Potent, Pyrazole-Based Inhibitors of Helicobacter p ylori Dihydroorotate Dehydrogenase TS Haque, S Tadesse, J Marcinkeviciene, MJ Rogers, C Sizemore, ... Journal of medicinal chemistry 45 (21), 4669-4678, 2002 | 92 | 2002 |
Searching for minimum increments of hydrophobic collapse: flexible dinaphthyl carboxylates LF Newcomb, TS Haque, SH Gellman Journal of the American Chemical Society 117 (24), 6509-6519, 1995 | 84 | 1995 |
Helicobacter pylori-selective antibacterials based on inhibition of pyrimidine biosynthesis RA Copeland, J Marcinkeviciene, TS Haque, LM Kopcho, W Jiang, ... Journal of Biological Chemistry 275 (43), 33373-33378, 2000 | 70 | 2000 |
Selective inhibition of bacterial dihydroorotate dehydrogenases by thiadiazolidinediones J Marcinkeviciene, MJ Rogers, L Kopcho, W Jiang, K Wang, DJ Murphy, ... Biochemical pharmacology 60 (3), 339-342, 2000 | 65 | 2000 |
Optimizing preparative LC/MS configurations and methods for parallel synthesis purification KF Blom, R Sparks, J Doughty, JG Everlof, T Haque, AP Combs Journal of Combinatorial Chemistry 5 (5), 670-683, 2003 | 51 | 2003 |
Structural Characterization of Thiocyclophanes That Promote Edge-to-Face Aromatic-Aromatic Geometries KD Schladetzky, TS Haque, SH Gellman The Journal of Organic Chemistry 60 (13), 4108-4113, 1995 | 51 | 1995 |
New evidence that the hydrophobic effect and dispersion are not major driving forces for nucleotide base stacking. SH Gellman, TS Haque, LF Newcomb Biophysical journal 71 (6), 3523, 1996 | 49 | 1996 |
N-Arylation of primary and secondary aliphatic amines on solid supports AP Combs, S Tadesse, M Rafalski, TS Haque, PYS Lam Journal of Combinatorial Chemistry 4 (2), 179-182, 2002 | 47 | 2002 |
Human glucagon-like-peptide-1 modulators and their use in treatment of diabetes and related conditions WR Ewing, C Mapelli, RB Sulsky, TS Haque, VG Lee, DJ Riexinger, ... US Patent 7,417,028, 2008 | 40 | 2008 |
Identification of potent 11mer glucagon-like peptide-1 receptor agonist peptides with novel C-terminal amino acids: homohomophenylalanine analogs TS Haque, VG Lee, D Riexinger, M Lei, S Malmstrom, L Xin, S Han, ... Peptides 31 (5), 950-955, 2010 | 26 | 2010 |
Pyrazolobenzamides and derivatives as factor Xa inhibitors PY Lam, CG Clark, R Li, TS Haque, KA Rossi US Patent 7,381,732, 2008 | 26 | 2008 |
Potent biphenyl-and 3-phenyl pyridine-based inhibitors of acetyl-CoA carboxylase TS Haque, N Liang, R Golla, R Seethala, Z Ma, WR Ewing, CB Cooper, ... Bioorganic & medicinal chemistry letters 19 (20), 5872-5876, 2009 | 24 | 2009 |
Differential activation of recombinant human acetyl-CoA carboxylases 1 and 2 by citrate GA Locke, D Cheng, MR Witmer, JK Tamura, T Haque, RF Carney, ... Archives of biochemistry and biophysics 475 (1), 72-79, 2008 | 24 | 2008 |
Liquid-liquid extraction coupled with LC/MS/MS for monitoring of malonyl-CoA in rat brain tissue JM Onorato, L Chen, P Shipkova, Z Ma, AV Azzara, JJ Devenny, N Liang, ... Analytical and bioanalytical chemistry 397, 3137-3142, 2010 | 22 | 2010 |