Par Nordlund
Par Nordlund
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Monitoring drug target engagement in cells and tissues using the cellular thermal shift assay
DM Molina, R Jafari, M Ignatushchenko, T Seki, EA Larsson, C Dan, ...
Science 341 (6141), 84-87, 2013
Ribonucleotide reductases
P Nordlund, P Reichard
Annu. Rev. Biochem. 75 (1), 681-706, 2006
Crystal structure of a bacterial non-haem iron hydroxylase that catalyses the biological oxidation of methane
AC Rosenzweig, CA Frederick, SJ Lippard, P Nordlund
Nature 366 (6455), 537-543, 1993
The cellular thermal shift assay for evaluating drug target interactions in cells
R Jafari, H Almqvist, H Axelsson, M Ignatushchenko, T Lundbäck, ...
Nature protocols 9 (9), 2100-2122, 2014
Three-dimensional structure of the free radical protein of ribonucleotide reductase
P Nordlund, BM Sjöberg, H Eklund
Nature 345 (6276), 593-598, 1990
Thermofluor-based high-throughput stability optimization of proteins for structural studies
UB Ericsson, BM Hallberg, GT DeTitta, N Dekker, P Nordlund
Analytical biochemistry 357 (2), 289-298, 2006
Tracking cancer drugs in living cells by thermal profiling of the proteome
MM Savitski, FBM Reinhard, H Franken, T Werner, MF Savitski, ...
Science 346 (6205), 1255784, 2014
Protein production and purification
Architecture et Fonction des Macromolécules Biologiques Vincentelli Renaud 4 ...
Nature methods 5 (2), 135-146, 2008
Chemical screening methods to identify ligands that promote protein stability, protein crystallization, and structure determination
M Vedadi, FH Niesen, A Allali-Hassani, OY Fedorov, PJ Finerty Jr, ...
Proceedings of the National Academy of Sciences 103 (43), 15835-15840, 2006
Structure and function of the Escherichia coli ribonucleotide reductase protein R2
P Nordlund, H Eklund
Journal of Molecular Biology 232 (1), 123-164, 1993
Geometry of the soluble methane monooxygenase catalytic diiron center in two oxidation states
AC Rosenzweig, P Nordlund, PM Takahara, CA Frederick, SJ Lippard
Chemistry & biology 2 (6), 409-418, 1995
Understanding transport by the major facilitator superfamily (MFS): structures pave the way
EM Quistgaard, C Löw, F Guettou, P Nordlund
Nature Reviews Molecular Cell Biology 17 (2), 123-132, 2016
Structure and function of the radical enzyme ribonucleotide reductase
H Eklund, U Uhlin, M Färnegårdh, DT Logan, P Nordlund
Progress in biophysics and molecular biology 77 (3), 177-268, 2001
Crystal structure of human leukotriene A4 hydrolase, a bifunctional enzyme in inflammation
MMGM Thunnissen, P Nordlund, JZ Haeggström
Nature structural biology 8 (2), 131-135, 2001
Crystal structure of reduced protein R2 of ribonucleotide reductase: the structural basis for oxygen activation at a dinuclear iron site
DT Logan, XD Su, A Åberg, K Regnström, J Hajdu, H Eklund, P Nordlund
Structure 4 (9), 1053-1064, 1996
Di-iron—carboxylate proteins
P Nordlund, H Eklund
Current opinion in structural biology 5 (6), 758-766, 1995
Green fluorescent protein as an indicator to monitor membrane protein overexpression in Escherichia coli
DE Drew, G Von Heijne, P Nordlund, JWL de Gier
FEBS letters 507 (2), 220-224, 2001
A saposin-lipoprotein nanoparticle system for membrane proteins
J Frauenfeld, R Löving, JP Armache, AFP Sonnen, F Guettou, P Moberg, ...
Nature methods 13 (4), 345-351, 2016
In situ proteolysis for protein crystallization and structure determination
A Dong, X Xu, AM Edwards
Nature methods 4 (12), 1019-1021, 2007
The cellular thermal shift assay: a novel biophysical assay for in situ drug target engagement and mechanistic biomarker studies
D Martinez Molina, P Nordlund
Annual review of pharmacology and toxicology 56 (1), 141-161, 2016
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