| SCYX-7158, an orally-active benzoxaborole for the treatment of stage 2 human African trypanosomiasis RT Jacobs, B Nare, SA Wring, MD Orr, D Chen, JM Sligar, MX Jenks, ... PLoS neglected tropical diseases 5 (6), e1151, 2011 | 354 | 2011 |
| Hydrogenosomes in the rumen fungus Neocallimastix patriciarum N Yarlett, CG Orpin, EA Munn, NC Yarlett, CA Greenwood Biochemical Journal 236 (3), 729-739, 1986 | 272 | 1986 |
| Hydrogenosomes in the rumen protozoon Dasytricha ruminantium Schuberg N Yarlett, AC Hann, D Lloyd, A Williams Biochemical Journal 200 (2), 365-372, 1981 | 168 | 1981 |
| Expression of cardiac cytokines and inducible form of nitric oxide synthase (NOS2) inTrypanosoma cruzi-infected mice H Huang, J Chan, M Wittner, LA Jelicks, SA Morris, SM Factor, LM Weiss, ... Journal of molecular and cellular cardiology 31 (1), 75-88, 1999 | 151 | 1999 |
| Continuous culture of Cryptosporidium parvum using hollow fiber technology M Morada, S Lee, L Gunther-Cummins, LM Weiss, G Widmer, S Tzipori, ... International journal for parasitology 46 (1), 21-29, 2016 | 131 | 2016 |
| Discovery of novel orally bioavailable oxaborole 6-carboxamides that demonstrate cure in a murine model of late-stage central nervous system african trypanosomiasis B Nare, S Wring, C Bacchi, B Beaudet, T Bowling, R Brun, D Chen, ... Antimicrobial agents and chemotherapy 54 (10), 4379-4388, 2010 | 117 | 2010 |
| Inducible resistance to oxidant stress in the protozoan Leishmania chagasi MA Miller, SE McGowan, KR Gantt, M Champion, SL Novick, ... Journal of Biological Chemistry 275 (43), 33883-33889, 2000 | 117 | 2000 |
| Antioxidant defences in the microaerophilic protozoan Trichomonas vaginalis: comparison of metronidazole-resistant and sensitive strains JE Ellis, N Yarlett, D Cole, MJ Humphreys, D Lloyd Microbiology 140 (9), 2489-2494, 1994 | 112 | 1994 |
| Cure of murine Trypanosoma brucei rhodesiense infections with an S-adenosylmethionine decarboxylase inhibitor CJ Bacchi, HC Nathan, N Yarlett, B Goldberg, PP McCann, AJ Bitonti, ... Antimicrobial agents and chemotherapy 36 (12), 2736-2740, 1992 | 106 | 1992 |
| Benzoxaboroles: a new class of potential drugs for human African trypanosomiasis RT Jacobs, JJ Plattner, B Nare, SA Wring, D Chen, Y Freund, EG Gaukel, ... Future medicinal chemistry 3 (10), 1259-1278, 2011 | 101 | 2011 |
| Discovery of novel benzoxaborole-based potent antitrypanosomal agents D Ding, Y Zhao, Q Meng, D Xie, B Nare, D Chen, CJ Bacchi, N Yarlett, ... ACS medicinal chemistry letters 1 (4), 165-169, 2010 | 101 | 2010 |
| Hydrogenosomes in known species of rumen entodiniomorphid protozoa N Yarlett, GS Coleman, AG Williams, D Lloyd FEMS Microbiology Letters 21 (1), 15-19, 1984 | 96 | 1984 |
| Metronidazole-resistant clinical isolates of Trichomonas vaginalis have lowered oxygen affinities N Yarlett, NC Yarlett, D Lloyd Molecular and biochemical parasitology 19 (2), 111-116, 1986 | 95 | 1986 |
| The presence of oxygen in rumen liquor and its effects on methanogenesis RI Scott, N Yarlett, K Hillman, AG Williams, D Lloyd, TN Williams Journal of Applied Microbiology 55 (1), 143-149, 1983 | 95 | 1983 |
| Hydrogenosomes in a mixed isolate of Isotricha prostoma and Isotricha intestinalis from ovine rumen contents. N Yarlett, AC Hann, D Lloyd, AG Williams Comparative Biochemistry and physiology. B, Comparative Biochemistry 74 (2 …, 1983 | 82 | 1983 |
| Polyamine metabolism as chemotherapeutic target in protozoan parasites CJ Bacchi, N Yarlett Mini reviews in medicinal chemistry 2 (6), 553-563, 2002 | 79 | 2002 |
| Resistance to dl-α-difluoromethylornithine by clinical isolates of Trypanosoma brucei rhodesiense: role of S-adenosylmethionine CJ Bacchi, J Garofalo, M Ciminelli, D Rattendi, B Goldberg, PP McCann, ... Biochemical pharmacology 46 (3), 471-481, 1993 | 79 | 1993 |
| Effect of DL-α-difluoromethylornithine on methionine cycle intermediates in Trypanosoma brucei brucei N Yarlett, CJ Bacchi Molecular and biochemical parasitology 27 (1), 1-10, 1988 | 79 | 1988 |
| Novel synthetic polyamines are effective in the treatment of experimental microsporidiosis, an opportunistic AIDS-associated infection CJ Bacchi, LM Weiss, S Lane, B Frydman, A Valasinas, V Reddy, JS Sun, ... Antimicrobial agents and chemotherapy 46 (1), 55-61, 2002 | 77 | 2002 |
| Polyamine biosynthesis in Cryptosporidium parvum and its implications for chemotherapy JS Keithly, G Zhu, SJ Upton, KM Woods, MP Martinez, N Yarlett Molecular and biochemical parasitology 88 (1-2), 35-42, 1997 | 76 | 1997 |
