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Gilles Truan
Gilles Truan
Verified email at insa-toulouse.fr
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The highly stereoselective oxidation of polyunsaturated fatty acids by cytochrome P450BM-3
JH Capdevila, S Wei, C Helvig, JR Falck, Y Belosludtsev, G Truan, ...
Journal of Biological Chemistry 271 (37), 22663-22671, 1996
2671996
An active site substitution, F87V, converts cytochrome P450 BM-3 into a regio-and stereoselective (14S, 15R)-arachidonic acid epoxygenase
S Graham-Lorence, G Truan, JA Peterson, JR Falck, S Wei, C Helvig, ...
Journal of Biological Chemistry 272 (2), 1127-1135, 1997
2551997
Gene2Oligo: oligonucleotide design for in vitro gene synthesis
JM Rouillard, W Lee, G Truan, X Gao, X Zhou, E Gulari
Nucleic acids research 32 (suppl_2), W176-W180, 2004
2022004
High efficiency family shuffling based on multi-step PCR and in vivo DNA recombination in yeast: statistical and functional analysis of a combinatorial library …
V Abécassis, D Pompon, G Truan
Nucleic acids research 28 (20), e88-e88, 2000
1872000
Enhanced in vivo monooxygenase activities of mammalian P450s in engineered yeast cells producing high levels of NADPH-P450 reductase and human cytochrome b5
G Truan, C Cullin, P Reisdorf, P Urban, D Pompon
Gene 125 (1), 49-55, 1993
1861993
Optimization of yeast‐expressed human liver cytochrome P450 3A4 catalytic activities by coexpressing NADPH‐cytochrome P450 reductase and cytochrome b5
MA PEYRONNEAU, JP RENAUD, G Truan, P Urban, D Pompon, ...
European journal of biochemistry 207 (1), 109-116, 1992
1211992
Cloning and characterization of a yeast cytochrome b5-encoding gene which suppresses ketoconazole hypersensitivity in a NADPH-P-450 reductase-deficient strain
G Truan, JC Epinat, C Rougeulle, C Cullin, D Pompon
Gene 142 (1), 123-127, 1994
931994
Structure of the open conformation of a functional chimeric NADPH cytochrome P450 reductase
L Aigrain, D Pompon, S Morera, G Truan
EMBO reports 10 (7), 742-747, 2009
912009
Thr268 in substrate binding and catalysis in P450BM-3
G Truan, JA Peterson
Archives of biochemistry and biophysics 349 (1), 53-64, 1998
881998
Ligand access channels in cytochrome P450 enzymes: A review
P Urban, T Lautier, D Pompon, G Truan
International Journal of Molecular Sciences 19 (6), 1617, 2018
722018
The flavoprotein domain of P450BM-3: expression, purification, and properties of the flavin adenine dinucleotide-and flavin mononucleotide-binding subdomains
I Sevrioukova, G Truan, JA Peterson
Biochemistry 35 (23), 7528-7535, 1996
661996
Recombinant yeast in drug metabolism
JP Renaud, MA Peyronneau, P Urban, G Truan, C Cullin, D Pompon, ...
Toxicology 82 (1-3), 39-52, 1993
581993
P450BM-3: absolute configuration of the primary metabolites of palmitic acid
G Truan, MR Komandla, JR Falck, JA Peterson
Archives of biochemistry and biophysics 366 (2), 192-198, 1999
571999
Xenobiotic metabolism in humanized yeast: engineered yeast cells producing human NADP H-cytochrome P-450 reductase, cytochrome b 5, epoxide hydrolase and P-450s
P Urban, G Truan, JC Gautier, D Pompon
Biochemical Society Transactions 21 (4), 1028-1034, 1993
541993
The closed and compact domain organization of the 70-kDa human cytochrome P450 reductase in its oxidized state as revealed by NMR
B Vincent, N Morellet, F Fatemi, L Aigrain, G Truan, E Guittet, E Lescop
Journal of molecular biology 420 (4-5), 296-309, 2012
532012
Enzyme-fusion strategies for redirecting and improving carotenoid synthesis in S. cerevisiae
H Rabeharindranto, S Castaño-Cerezo, T Lautier, LF Garcia-Alles, ...
Metabolic engineering communications 8, e00086, 2019
482019
A single-step procedure of recombinant library construction for the selection of efficiently produced llama VH binders directed against cancer markers
D Kastelic, S Frković-Grazio, D Baty, G Truan, R Komel, D Pompon
Journal of immunological methods 350 (1-2), 54-62, 2009
452009
The promise of optogenetics for bioproduction: dynamic control strategies and scale-up instruments
S Pouzet, A Banderas, M Le Bec, T Lautier, G Truan, P Hersen
Bioengineering 7 (4), 151, 2020
442020
Reconstitution of the fatty acid hydroxylase activity of cytochrome P450BM-3 utilizing its functional domains
I Sevrioukova, G Truan, JA Peterson
Archives of biochemistry and biophysics 340 (2), 231-238, 1997
391997
Role of the interface between the FMN and FAD domains in the control of redox potential and electronic transfer of NADPH–cytochrome P450 reductase
L Aigrain, D Pompon, G Truan
Biochemical journal 435 (1), 197-206, 2011
372011
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