The highly stereoselective oxidation of polyunsaturated fatty acids by cytochrome P450BM-3 JH Capdevila, S Wei, C Helvig, JR Falck, Y Belosludtsev, G Truan, ... Journal of Biological Chemistry 271 (37), 22663-22671, 1996 | 267 | 1996 |
An active site substitution, F87V, converts cytochrome P450 BM-3 into a regio-and stereoselective (14S, 15R)-arachidonic acid epoxygenase S Graham-Lorence, G Truan, JA Peterson, JR Falck, S Wei, C Helvig, ... Journal of Biological Chemistry 272 (2), 1127-1135, 1997 | 255 | 1997 |
Gene2Oligo: oligonucleotide design for in vitro gene synthesis JM Rouillard, W Lee, G Truan, X Gao, X Zhou, E Gulari Nucleic acids research 32 (suppl_2), W176-W180, 2004 | 202 | 2004 |
High efficiency family shuffling based on multi-step PCR and in vivo DNA recombination in yeast: statistical and functional analysis of a combinatorial library … V Abécassis, D Pompon, G Truan Nucleic acids research 28 (20), e88-e88, 2000 | 187 | 2000 |
Enhanced in vivo monooxygenase activities of mammalian P450s in engineered yeast cells producing high levels of NADPH-P450 reductase and human cytochrome b5 G Truan, C Cullin, P Reisdorf, P Urban, D Pompon Gene 125 (1), 49-55, 1993 | 186 | 1993 |
Optimization of yeast‐expressed human liver cytochrome P450 3A4 catalytic activities by coexpressing NADPH‐cytochrome P450 reductase and cytochrome b5 MA PEYRONNEAU, JP RENAUD, G Truan, P Urban, D Pompon, ... European journal of biochemistry 207 (1), 109-116, 1992 | 121 | 1992 |
Cloning and characterization of a yeast cytochrome b5-encoding gene which suppresses ketoconazole hypersensitivity in a NADPH-P-450 reductase-deficient strain G Truan, JC Epinat, C Rougeulle, C Cullin, D Pompon Gene 142 (1), 123-127, 1994 | 93 | 1994 |
Structure of the open conformation of a functional chimeric NADPH cytochrome P450 reductase L Aigrain, D Pompon, S Morera, G Truan EMBO reports 10 (7), 742-747, 2009 | 91 | 2009 |
Thr268 in substrate binding and catalysis in P450BM-3 G Truan, JA Peterson Archives of biochemistry and biophysics 349 (1), 53-64, 1998 | 88 | 1998 |
Ligand access channels in cytochrome P450 enzymes: A review P Urban, T Lautier, D Pompon, G Truan International Journal of Molecular Sciences 19 (6), 1617, 2018 | 72 | 2018 |
The flavoprotein domain of P450BM-3: expression, purification, and properties of the flavin adenine dinucleotide-and flavin mononucleotide-binding subdomains I Sevrioukova, G Truan, JA Peterson Biochemistry 35 (23), 7528-7535, 1996 | 66 | 1996 |
Recombinant yeast in drug metabolism JP Renaud, MA Peyronneau, P Urban, G Truan, C Cullin, D Pompon, ... Toxicology 82 (1-3), 39-52, 1993 | 58 | 1993 |
P450BM-3: absolute configuration of the primary metabolites of palmitic acid G Truan, MR Komandla, JR Falck, JA Peterson Archives of biochemistry and biophysics 366 (2), 192-198, 1999 | 57 | 1999 |
Xenobiotic metabolism in humanized yeast: engineered yeast cells producing human NADP H-cytochrome P-450 reductase, cytochrome b 5, epoxide hydrolase and P-450s P Urban, G Truan, JC Gautier, D Pompon Biochemical Society Transactions 21 (4), 1028-1034, 1993 | 54 | 1993 |
The closed and compact domain organization of the 70-kDa human cytochrome P450 reductase in its oxidized state as revealed by NMR B Vincent, N Morellet, F Fatemi, L Aigrain, G Truan, E Guittet, E Lescop Journal of molecular biology 420 (4-5), 296-309, 2012 | 53 | 2012 |
Enzyme-fusion strategies for redirecting and improving carotenoid synthesis in S. cerevisiae H Rabeharindranto, S Castaño-Cerezo, T Lautier, LF Garcia-Alles, ... Metabolic engineering communications 8, e00086, 2019 | 48 | 2019 |
A single-step procedure of recombinant library construction for the selection of efficiently produced llama VH binders directed against cancer markers D Kastelic, S Frković-Grazio, D Baty, G Truan, R Komel, D Pompon Journal of immunological methods 350 (1-2), 54-62, 2009 | 45 | 2009 |
The promise of optogenetics for bioproduction: dynamic control strategies and scale-up instruments S Pouzet, A Banderas, M Le Bec, T Lautier, G Truan, P Hersen Bioengineering 7 (4), 151, 2020 | 44 | 2020 |
Reconstitution of the fatty acid hydroxylase activity of cytochrome P450BM-3 utilizing its functional domains I Sevrioukova, G Truan, JA Peterson Archives of biochemistry and biophysics 340 (2), 231-238, 1997 | 39 | 1997 |
Role of the interface between the FMN and FAD domains in the control of redox potential and electronic transfer of NADPH–cytochrome P450 reductase L Aigrain, D Pompon, G Truan Biochemical journal 435 (1), 197-206, 2011 | 37 | 2011 |