Tom W. Muir
Tom W. Muir
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Synthesis of proteins by native chemical ligation
PE Dawson, TW Muir, I Clark-Lewis, SBH Kent
Science 266 (5186), 776-779, 1994
Expressed protein ligation: a general method for protein engineering
TW Muir, D Sondhi, PA Cole
Proceedings of the National Academy of Sciences 95 (12), 6705-6710, 1998
Inhibition of PRC2 activity by a gain-of-function H3 mutation found in pediatric glioblastoma
PW Lewis, MM Müller, MS Koletsky, F Cordero, S Lin, LA Banaszynski, ...
Science 340 (6134), 857-861, 2013
Semisynthesis of proteins by expressed protein ligation
TW Muir
Annual review of biochemistry 72 (1), 249-289, 2003
Histone H2A deubiquitinase activity of the Polycomb repressive complex PR-DUB
JC Scheuermann, AG de Ayala Alonso, K Oktaba, N Ly-Hartig, ...
Nature 465 (7295), 243-247, 2010
How many human proteoforms are there?
R Aebersold, JN Agar, IJ Amster, MS Baker, CR Bertozzi, ES Boja, ...
Nature chemical biology 14 (3), 206-214, 2018
Structure-activity analysis of synthetic autoinducing thiolactone peptides from Staphylococcus aureus responsible for virulence
P Mayville, G Ji, R Beavis, H Yang, M Goger, RP Novick, TW Muir
Proceedings of the National Academy of Sciences 96 (4), 1218-1223, 1999
Chemically ubiquitylated histone H2B stimulates hDot1L-mediated intranucleosomal methylation
RK McGinty, J Kim, C Chatterjee, RG Roeder, TW Muir
Nature 453 (7196), 812-816, 2008
RAD6-Mediated transcription-coupled H2B ubiquitylation directly stimulates H3K4 methylation in human cells
J Kim, M Guermah, RK McGinty, JS Lee, Z Tang, TA Milne, A Shilatifard, ...
Cell 137 (3), 459-471, 2009
The TGFβ receptor activation process: an inhibitor-to substrate-binding switch
M Huse, TW Muir, L Xu, YG Chen, J Kuriyan, J Massagué
Molecular cell 8 (3), 671-682, 2001
Histone H2B ubiquitylation disrupts local and higher-order chromatin compaction
B Fierz, C Chatterjee, RK McGinty, M Bar-Dagan, DP Raleigh, TW Muir
Nature chemical biology 7 (2), 113-119, 2011
Protein ligation: an enabling technology for the biophysical analysis of proteins
V Muralidharan, TW Muir
Nature methods 3 (6), 429-438, 2006
Inteins: nature's gift to protein chemists
NH Shah, TW Muir
Chemical science 5 (2), 446-461, 2014
Crystal structure of a phosphorylated Smad2: Recognition of phosphoserine by the MH2 domain and insights on Smad function in TGF-β signaling
JW Wu, M Hu, J Chai, J Seoane, M Huse, C Li, DJ Rigotti, S Kyin, TW Muir, ...
Molecular cell 8 (6), 1277-1289, 2001
Recognition of a mononucleosomal histone modification pattern by BPTF via multivalent interactions
AJ Ruthenburg, H Li, TA Milne, S Dewell, RK McGinty, M Yuen, ...
Cell 145 (5), 692-706, 2011
Histone H3K36 mutations promote sarcomagenesis through altered histone methylation landscape
C Lu, SU Jain, D Hoelper, D Bechet, RC Molden, L Ran, D Murphy, ...
Science 352 (6287), 844-849, 2016
Histone serotonylation is a permissive modification that enhances TFIID binding to H3K4me3
LA Farrelly, RE Thompson, S Zhao, AE Lepack, Y Lyu, NV Bhanu, ...
Nature 567 (7749), 535-539, 2019
Exfoliatin-Producing Strains Define a Fourthagr Specificity Group in Staphylococcus aureus
S Jarraud, GJ Lyon, AMS Figueiredo, L Gérard, F Vandenesch, J Etienne, ...
Journal of bacteriology 182 (22), 6517-6522, 2000
Rational design of a global inhibitor of the virulence response in Staphylococcus aureus, based in part on localization of the site of inhibition to the receptor …
GJ Lyon, P Mayville, TW Muir, RP Novick
Proceedings of the National Academy of Sciences 97 (24), 13330-13335, 2000
Chemical ligation of folded recombinant proteins: segmental isotopic labeling of domains for NMR studies
R Xu, B Ayers, D Cowburn, TW Muir
Proceedings of the National Academy of Sciences 96 (2), 388-393, 1999
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