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Alexandra L Garnham
Alexandra L Garnham
Verified email at wehi.edu.au
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Cited by
Year
Inhibitors of histone acetyltransferases KAT6A/B induce senescence and arrest tumour growth
JB Baell, DJ Leaver, SJ Hermans, GL Kelly, MS Brennan, NL Downer, ...
Nature 560 (7717), 253-257, 2018
2362018
The neuropeptide VIP confers anticipatory mucosal immunity by regulating ILC3 activity
C Seillet, K Luong, J Tellier, N Jacquelot, RD Shen, P Hickey, VC Wimmer, ...
Nature immunology 21 (2), 168-177, 2020
1732020
The TNF receptor superfamily-NF-κB axis is critical to maintain effector regulatory T cells in lymphoid and non-lymphoid tissues
A Vasanthakumar, Y Liao, P Teh, MF Pascutti, AE Oja, AL Garnham, ...
Cell reports 20 (12), 2906-2920, 2017
1392017
SIDT2 transports extracellular dsRNA into the cytoplasm for innate immune recognition
TA Nguyen, BRC Smith, MD Tate, GT Belz, MH Barrios, KD Elgass, ...
Immunity 47 (3), 498-509. e6, 2017
1362017
Flexible usage and interconnectivity of diverse cell death pathways protect against intracellular infection
M Doerflinger, Y Deng, P Whitney, R Salvamoser, S Engel, AJ Kueh, L Tai, ...
Immunity 53 (3), 533-547. e7, 2020
1222020
An aspartyl protease defines a novel pathway for export of Toxoplasma proteins into the host cell
MJ Coffey, BE Sleebs, AD Uboldi, A Garnham, M Franco, ND Marino, ...
Elife 4, e10809, 2015
1192015
Attenuation of TCR-induced transcription by Bach2 controls regulatory T cell differentiation and homeostasis
T Sidwell, Y Liao, AL Garnham, A Vasanthakumar, R Gloury, J Blume, ...
Nature Communications 11 (1), 252, 2020
782020
Glutaminase inhibition impairs CD8 T cell activation in STK11-/Lkb1-deficient lung cancer
SA Best, PM Gubser, S Sethumadhavan, A Kersbergen, YLN Abril, ...
Cell Metabolism 34 (6), 874-887. e6, 2022
772022
Extracellular vesicles from early stage Plasmodium falciparum‐infected red blood cells contain PfEMP1 and induce transcriptional changes in human monocytes
NG Sampaio, SJ Emery, AL Garnham, QY Tan, X Sisquella, MA Pimentel, ...
Cellular Microbiology 20 (5), e12822, 2018
732018
Single-cell multiomics reveal the scale of multilayered adaptations enabling CLL relapse during venetoclax therapy
R Thijssen, L Tian, MA Anderson, C Flensburg, A Jarratt, AL Garnham, ...
Blood, The Journal of the American Society of Hematology 140 (20), 2127-2141, 2022
612022
Responses of the Differentiated Intestinal Epithelial Cell Line Caco-2 to Infection With the Giardia intestinalis GS Isolate
SY Ma'Ayeh, L Knörr, K Sköld, A Garnham, BRE Ansell, AR Jex, SG Svärd
Frontiers in cellular and infection microbiology 8, 244, 2018
472018
Multi-level remodelling of chromatin underlying activation of human T cells
NG Bediaga, HD Coughlan, TM Johanson, AL Garnham, G Naselli, ...
Scientific reports 11 (1), 528, 2021
462021
Dysregulated IL-1β-GM-CSF axis in acute rheumatic fever that is limited by hydroxychloroquine
ML Kim, WJ Martin, G Minigo, JL Keeble, AL Garnham, G Pacini, ...
Circulation 138 (23), 2648-2661, 2018
422018
Necroptosis is dispensable for the development of inflammation-associated or sporadic colon cancer in mice
S Alvarez-Diaz, A Preaudet, AL Samson, PM Nguyen, KY Fung, ...
Cell Death & Differentiation 28 (5), 1466-1476, 2021
412021
PHF6 regulates hematopoietic stem and progenitor cells and its loss synergizes with expression of TLX3 to cause leukemia
HM McRae, AL Garnham, Y Hu, MT Witkowski, MA Corbett, MP Dixon, ...
Blood, The Journal of the American Society of Hematology 133 (16), 1729-1741, 2019
412019
Acute myeloid leukemia requires Hhex to enable PRC2-mediated epigenetic repression of Cdkn2a
BJ Shields, JT Jackson, D Metcalf, W Shi, Q Huang, AL Garnham, ...
Genes & development 30 (1), 78-91, 2016
402016
The histone lysine acetyltransferase HBO1 (KAT7) regulates hematopoietic stem cell quiescence and self-renewal
Y Yang, AJ Kueh, ZL Grant, W Abeysekera, AL Garnham, S Wilcox, ...
Blood, The Journal of the American Society of Hematology 139 (6), 845-858, 2022
392022
Design, synthesis, and biological activity of 1, 2, 3-triazolobenzodiazepine BET bromodomain inhibitors
PP Sharp, JM Garnier, T Hatfaludi, Z Xu, D Segal, KE Jarman, H Jousset, ...
ACS Medicinal Chemistry Letters 8 (12), 1298-1303, 2017
332017
Impaired social behaviour and molecular mediators of associated neural circuits during chronic Toxoplasma gondii infection in female mice
S Tyebji, S Seizova, AL Garnham, AJ Hannan, CJ Tonkin
Brain, behavior, and immunity 80, 88-108, 2019
322019
Extracellular vesicles in synovial fluid from rheumatoid arthritis patients contain miRNAs with capacity to modulate inflammation
AD Foers, AL Garnham, S Chatfield, GK Smyth, L Cheng, AF Hill, IP Wicks, ...
International Journal of Molecular Sciences 22 (9), 4910, 2021
292021
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