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Jon Clardy
Jon Clardy
Professor of Biological Chemistry, Harvard Medical School
Verified email at hms.harvard.edu
Title
Cited by
Cited by
Year
Molecular biological access to the chemistry of unknown soil microbes: a new frontier for natural products
J Handelsman, MR Rondon, SF Brady, J Clardy, RM Goodman
Chemistry & biology 5 (10), R245-R249, 1998
28181998
Ribosomally synthesized and post-translationally modified peptide natural products: overview and recommendations for a universal nomenclature
PG Arnison, MJ Bibb, G Bierbaum, AA Bowers, TS Bugni, G Bulaj, ...
Natural product reports 30 (1), 108-160, 2013
20522013
Cloning the soil metagenome: a strategy for accessing the genetic and functional diversity of uncultured microorganisms
MR Rondon, PR August, AD Bettermann, SF Brady, TH Grossman, ...
Applied and environmental microbiology 66 (6), 2541-2547, 2000
17442000
Lessons from natural molecules
J Clardy, C Walsh
Nature 432 (7019), 829-837, 2004
15692004
Atomic structures of the human immunophilin FKBP-12 complexes with FK506 and rapamycin
GD Van Duyne, RF Standaert, PA Karplus, SL Schreiber, J Clardy
Journal of molecular biology 229 (1), 105-124, 1993
14521993
Structure of the FKBP12-rapamycin complex interacting with binding domain of human FRAP
J Choi, J Chen, SL Schreiber, J Clardy
Science 273 (5272), 239-242, 1996
11361996
Okadaic acid, a cytotoxic polyether from two marine sponges of the genus Halichondria
K Tachibana, PJ Scheuer, Y Tsukitani, H Kikuchi, D Van Engen, J Clardy, ...
Journal of the American Chemical Society 103 (9), 2469-2471, 1981
10551981
D-amino acids trigger biofilm disassembly
I Kolodkin-Gal, D Romero, S Cao, J Clardy, R Kolter, R Losick
Science 328 (5978), 627-629, 2010
10422010
Isolation and structure of bryostatin 1
GR Pettit, CL Herald, DL Doubek, DL Herald, E Arnold, J Clardy
Journal of the American Chemical Society 104 (24), 6846-6848, 1982
9731982
Insights into secondary metabolism from a global analysis of prokaryotic biosynthetic gene clusters
P Cimermancic, MH Medema, J Claesen, K Kurita, LCW Brown, ...
Cell 158 (2), 412-421, 2014
9582014
Target identification using drug affinity responsive target stability (DARTS)
B Lomenick, R Hao, N Jonai, RM Chin, M Aghajan, S Warburton, J Wang, ...
Proceedings of the National Academy of Sciences 106 (51), 21984-21989, 2009
9112009
Diarrhetic shellfish toxins
T Yasumoto, M Murata, Y Oshima, M Sano, GK Matsumoto, J Clardy
Tetrahedron 41 (6), 1019-1025, 1985
8661985
Minimum information about a biosynthetic gene cluster
MH Medema, R Kottmann, P Yilmaz, M Cummings, JB Biggins, K Blin, ...
Nature chemical biology 11 (9), 625-631, 2015
8642015
GABA-modulating bacteria of the human gut microbiota
P Strandwitz, KH Kim, D Terekhova, JK Liu, A Sharma, J Levering, ...
Nature microbiology 4 (3), 396-403, 2019
8072019
Atomic structure of FKBP-FK506, an immunophilin-immunosuppressant complex
GD Van Duyne, RF Standaert, PA Karplus, SL Schreiber, J Clardy
Science 252 (5007), 839-842, 1991
7841991
New antibiotics from bacterial natural products
J Clardy, MA Fischbach, CT Walsh
Nature biotechnology 24 (12), 1541-1550, 2006
7812006
Isolation and structure of brevetoxin B from the" red tide" dinoflagellate Ptychodiscus brevis (Gymnodinium breve)
YY Lin, M Risk, SM Ray, D Van Engen, J Clardy, J Golik, JC James, ...
Journal of the American Chemical Society 103 (22), 6773-6775, 1981
7231981
Isolation of antibiotics turbomycin A and B from a metagenomic library of soil microbial DNA
DE Gillespie, SF Brady, AD Bettermann, NP Cianciotto, MR Liles, ...
Applied and environmental microbiology 68 (9), 4301-4306, 2002
7132002
D-amino acids govern stationary phase cell wall remodeling in bacteria
H Lam, DC Oh, F Cava, CN Takacs, J Clardy, MA de Pedro, MK Waldor
Science 325 (5947), 1552-1555, 2009
6852009
A systematic analysis of biosynthetic gene clusters in the human microbiome reveals a common family of antibiotics
MS Donia, P Cimermancic, CJ Schulze, LCW Brown, J Martin, M Mitreva, ...
Cell 158 (6), 1402-1414, 2014
6712014
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