| Total synthesis of (±)-stemonamide and (±)-isostemonamide AS Kende, JIM Hernando, JBJ Milbank Tetrahedron 58 (1), 61-74, 2002 | 86 | 2002 |
| Identification of potential aryl hydrocarbon receptor antagonists in green tea CM Palermo, JIM Hernando, SD Dertinger, AS Kende, TA Gasiewicz Chemical research in toxicology 16 (7), 865-872, 2003 | 83 | 2003 |
| First total synthesis of (±)-stemonamide and (±)-isostemonamide AS Kende, JI Martin Hernando, JBJ Milbank Organic letters 3 (16), 2505-2508, 2001 | 67 | 2001 |
| Identification of thieno[3,2-b]pyrroles as allosteric inhibitors of hepatitis C virus NS5B polymerase JM Ontoria, JIM Hernando, S Malancona, B Attenni, I Stansfield, I Conte, ... Bioorganic & medicinal chemistry letters 16 (15), 4026-4030, 2006 | 61 | 2006 |
| Identification and Biological Evaluation of a Series of 1H-Benzo[de]isoquinoline-1,3(2H)-diones as Hepatitis C Virus NS5B Polymerase Inhibitors JM Ontoria, EH Rydberg, S Di Marco, L Tomei, B Attenni, S Malancona, ... Journal of medicinal chemistry 52 (16), 5217-5227, 2009 | 56 | 2009 |
| Identification of MK-5710 ((8aS)-8a-methyl-1, 3-dioxo-2-[(1S, 2R)-2-phenylcyclo-propyl]-N-(1-phenyl-1H-pyrazol-5-yl) hexahydro-imidazo [1, 5-a] pyrazine-7 (1H)-carboxamide), a … O Kinzel, A Alfieri, S Altamura, M Brunetti, S Bufali, F Colaceci, F Ferrigno, ... Bioorganic & medicinal chemistry letters 21 (15), 4429-4435, 2011 | 47 | 2011 |
| Optimization of thienopyrrole‐based finger‐loop inhibitors of the hepatitis C virus NS5B polymerase JI Martin Hernando, JM Ontoria, S Malancona, B Attenni, F Fiore, F Bonelli, ... ChemMedChem: Chemistry Enabling Drug Discovery 4 (10), 1695-1713, 2009 | 41 | 2009 |
| Allosteric inhibitors of hepatitis C virus NS5B polymerase thumb domain site II: structure-based design and synthesis of new templates S Malancona, M Donghi, M Ferrara, JIM Hernando, M Pompei, S Pesci, ... Bioorganic & medicinal chemistry 18 (8), 2836-2848, 2010 | 38 | 2010 |
| Identification of MK-5710 ((8aS)-8a-methyl-1, 3-dioxo-2-[(1S, 2R)-2-phenylcyclopropyl]-N-(1-phenyl-1H-pyrazol-5-yl) hexahydroimid azo [1, 5-a] pyrazine-7 (1H)-carboxamide), a … S Malancona, S Altamura, G Filocamo, O Kinzel, JIM Hernando, ... Bioorganic & medicinal chemistry letters 21 (15), 4422-4428, 2011 | 37 | 2011 |
| Inhibitors of hepatitis C virus NS3/4A: α-Ketoamide based macrocyclic inhibitors S Avolio, K Robertson, JIM Hernando, J DiMuzio, V Summa Bioorganic & medicinal chemistry letters 19 (8), 2295-2298, 2009 | 36 | 2009 |
| Development of Chemical Entities Endowed with Potent Fast-Killing Properties against Plasmodium falciparum Malaria Parasites AN Matralis, A Malik, M Penzo, I Moreno, MJ Almela, I Camino, B Crespo, ... Journal of medicinal chemistry 62 (20), 9217-9235, 2019 | 34 | 2019 |
| Identification of ETP-46321, a potent and orally bioavailable PI3K α, δ inhibitor SM González, AI Hernández, C Varela, S Rodríguez-Arístegui, M Lorenzo, ... Bioorganic & medicinal chemistry letters 22 (10), 3460-3466, 2012 | 29 | 2012 |
| Oxidative cleavage of unsaturated 1, 2-diols using chiral lead-tetracarboxylates obtained by in situ metathesis JIC Lena, Ö Sesenoglu, N Birlirakis, S Arseniyadis Tetrahedron Letters 42 (1), 21-24, 2001 | 29 | 2001 |
| Influence of the substitution pattern on the Pb(OAc)4 mediated oxidative cleavage of steroidal 1,2-diols JIM Hernando, MRR Ferreira, JIC Lena, L Toupet, N Birlirakis, ... Tetrahedron: Asymmetry 10 (20), 3977-3989, 1999 | 21 | 1999 |
| Taxoid C-ring building blocks from Hajos–Parrish ketone. Practical synthesis of an enantiomerically pure taxoid ABC ring system JIM Hernando, JQ del Moral, MRR Ferreira, JIC Lena, S Arseniyadis Tetrahedron: Asymmetry 10 (4), 783-797, 1999 | 21 | 1999 |
| Different approaches to the asymmetric synthesis of 1, 3, 6-trisubstituted and 1, 2, 3, 6-tetrasubstituted carbapenems1 from D-glucosamine J Anaya, DHR Barton, SD Gero, M Grande, JIM Hernando, NM Laso Tetrahedron: Asymmetry 6 (2), 609-624, 1995 | 20 | 1995 |
| Macrocyclic compounds as protein kinase inhibitors JP Fernández, RMÁ Escobar, RCR Fagundo, ABG García, AR Hergueta, ... US Patent 9,284,334, 2016 | 18 | 2016 |
| Tandem glycol cleavage—intramolecular 4+2 cycloadditions mediated by Mn(OAc)3 JIC Lena, MRR Ferreira, JIM Hernando, E Altınel, S Arseniyadis Tetrahedron Letters 42 (18), 3179-3182, 2001 | 18 | 2001 |
| Modified steroids: Pb(OAc)4 mediated one-pot multistage transformations of steroidal unsaturated 1,2-diols MRR Ferreira, JIM Hernando, JIC Lena, JQ del Moral, S Arseniyadis Tetrahedron: Asymmetry 10 (8), 1527-1537, 1999 | 18 | 1999 |
| Studies towards the taxoid diterpene ABC-ring system: practical access to highly functionalized enantiomerically pure analogues of major group representatives JIM Hernando, MRR Ferreira, JIC Lena, N Birlirakis, S Arseniyadis Tetrahedron: Asymmetry 11 (4), 951-973, 2000 | 17 | 2000 |
Michael RowleyMedicinal Chemistry Consultant, Xelaro LtdVerified email at mrowley.com
