A physical and functional map of the human TNF-α/NF-κB signal transduction pathway T Bouwmeester, A Bauch, H Ruffner, PO Angrand, G Bergamini, ... Nature cell biology 6 (2), 97-105, 2004 | 1335 | 2004 |
Quantitative chemical proteomics reveals mechanisms of action of clinical ABL kinase inhibitors M Bantscheff, D Eberhard, Y Abraham, S Bastuck, M Boesche, S Hobson, ... Nature biotechnology 25 (9), 1035-1044, 2007 | 1227 | 2007 |
Tracking cancer drugs in living cells by thermal profiling of the proteome MM Savitski, FBM Reinhard, H Franken, T Werner, MF Savitski, ... Science 346 (6205), 1255784, 2014 | 1096 | 2014 |
A selective jumonji H3K27 demethylase inhibitor modulates the proinflammatory macrophage response L Kruidenier, C Chung, Z Cheng, J Liddle, KH Che, G Joberty, ... Nature 488 (7411), 404-408, 2012 | 981 | 2012 |
Chemoproteomics profiling of HDAC inhibitors reveals selective targeting of HDAC complexes M Bantscheff, C Hopf, MM Savitski, A Dittmann, P Grandi, AM Michon, ... Nature biotechnology 29 (3), 255-265, 2011 | 790 | 2011 |
Inhibition of PAD4 activity is sufficient to disrupt mouse and human NET formation HD Lewis, J Liddle, JE Coote, SJ Atkinson, MD Barker, BD Bax, KL Bicker, ... Nature chemical biology 11 (3), 189-191, 2015 | 710 | 2015 |
Thermal proteome profiling monitors ligand interactions with cellular membrane proteins FBM Reinhard, D Eberhard, T Werner, H Franken, D Childs, C Doce, ... Nature methods 12 (12), 1129-1131, 2015 | 309 | 2015 |
Transcriptional repression by Pax5 (BSAP) through interaction with corepressors of the Groucho family D Eberhard, G Jiménez, B Heavey, M Busslinger The EMBO journal, 2000 | 304 | 2000 |
Robust and sensitive iTRAQ quantification on an LTQ Orbitrap mass spectrometer M Bantscheff, M Boesche, D Eberhard, T Matthieson, G Sweetman, ... Molecular & Cellular Proteomics 7 (9), 1702-1713, 2008 | 298 | 2008 |
Biological plasticity rescues target activity in CRISPR knock outs AH Smits, F Ziebell, G Joberty, N Zinn, WF Mueller, S Clauder-Münster, ... Nature methods 16 (11), 1087-1093, 2019 | 231 | 2019 |
Pax5 determines the identity of B cells from the beginning to the end of B-lymphopoiesis SL Nutt, D Eberhard, M Horcher, AG Rolink, M Busslinger International reviews of immunology 20 (1), 65-82, 2001 | 160 | 2001 |
The N‐terminal domain of the human TATA‐binding protein plays a role in transcription from TATA‐containing RNA polymerase II and III promoters. A Lescure, Y Lutz, D Eberhard, X Jacq, A Krol, I Grummt, I Davidson, ... The EMBO journal 13 (5), 1166-1175, 1994 | 142 | 1994 |
A TBP-containing multiprotein complex (TIF-IB) mediates transcription specificity of murine RNA polymerase I D Eberhard, L Tora, JM Egly, I Grummt Nucleic acids research 21 (18), 4180-4186, 1993 | 119 | 1993 |
The partial homeodomain of the transcription factor Pax-5 (BSAP) is an interaction motif for the retinoblastoma and TATA-binding proteins D Eberhard, M Busslinger Cancer research 59 (7_Supplement), 1716s-1725s, 1999 | 105 | 1999 |
Chemoproteomics-based kinome profiling and target deconvolution of clinical multi-kinase inhibitors in primary chronic lymphocytic leukemia cells U Kruse, CP Pallasch, M Bantscheff, D Eberhard, L Frenzel, S Ghidelli, ... Leukemia 25 (1), 89-100, 2011 | 87 | 2011 |
Corecruitment of the Grg4 repressor by PU. 1 is critical for Pax5‐mediated repression of B‐cell‐specific genes Y Linderson, D Eberhard, S Malin, A Johansson, M Busslinger, ... EMBO reports 5 (3), 291-296, 2004 | 82 | 2004 |
TBP‐associated factors interact with DNA and govern species specificity of RNA polymerase I transcription. U Rudloff, D Eberhard, L Tora, H Stunnenberg, I Grummt The EMBO Journal 13 (11), 2611-2616, 1994 | 78 | 1994 |
Chemical Proteomic Analysis Reveals the Drugability of the Kinome of Trypanosoma brucei MD Urbaniak, T Mathieson, M Bantscheff, D Eberhard, R Grimaldi, ... ACS chemical biology 7 (11), 1858-1865, 2012 | 62 | 2012 |
Gbx2 and Otx2 interact with the WD40 domain of Groucho/Tle corepressors T Heimbucher, C Murko, B Bajoghli, N Aghaallaei, A Huber, R Stebegg, ... Molecular and cellular biology 27 (1), 340-351, 2007 | 54 | 2007 |
Interrogating the druggability of the 2-oxoglutarate-dependent dioxygenase target class by chemical proteomics G Joberty, M Boesche, JA Brown, D Eberhard, NS Garton, PG Humphreys, ... ACS chemical biology 11 (7), 2002-2010, 2016 | 40 | 2016 |