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Dirk Eberhard
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A physical and functional map of the human TNF-α/NF-κB signal transduction pathway
T Bouwmeester, A Bauch, H Ruffner, PO Angrand, G Bergamini, ...
Nature cell biology 6 (2), 97-105, 2004
13352004
Quantitative chemical proteomics reveals mechanisms of action of clinical ABL kinase inhibitors
M Bantscheff, D Eberhard, Y Abraham, S Bastuck, M Boesche, S Hobson, ...
Nature biotechnology 25 (9), 1035-1044, 2007
12272007
Tracking cancer drugs in living cells by thermal profiling of the proteome
MM Savitski, FBM Reinhard, H Franken, T Werner, MF Savitski, ...
Science 346 (6205), 1255784, 2014
10962014
A selective jumonji H3K27 demethylase inhibitor modulates the proinflammatory macrophage response
L Kruidenier, C Chung, Z Cheng, J Liddle, KH Che, G Joberty, ...
Nature 488 (7411), 404-408, 2012
9812012
Chemoproteomics profiling of HDAC inhibitors reveals selective targeting of HDAC complexes
M Bantscheff, C Hopf, MM Savitski, A Dittmann, P Grandi, AM Michon, ...
Nature biotechnology 29 (3), 255-265, 2011
7902011
Inhibition of PAD4 activity is sufficient to disrupt mouse and human NET formation
HD Lewis, J Liddle, JE Coote, SJ Atkinson, MD Barker, BD Bax, KL Bicker, ...
Nature chemical biology 11 (3), 189-191, 2015
7102015
Thermal proteome profiling monitors ligand interactions with cellular membrane proteins
FBM Reinhard, D Eberhard, T Werner, H Franken, D Childs, C Doce, ...
Nature methods 12 (12), 1129-1131, 2015
3092015
Transcriptional repression by Pax5 (BSAP) through interaction with corepressors of the Groucho family
D Eberhard, G Jiménez, B Heavey, M Busslinger
The EMBO journal, 2000
3042000
Robust and sensitive iTRAQ quantification on an LTQ Orbitrap mass spectrometer
M Bantscheff, M Boesche, D Eberhard, T Matthieson, G Sweetman, ...
Molecular & Cellular Proteomics 7 (9), 1702-1713, 2008
2982008
Biological plasticity rescues target activity in CRISPR knock outs
AH Smits, F Ziebell, G Joberty, N Zinn, WF Mueller, S Clauder-Münster, ...
Nature methods 16 (11), 1087-1093, 2019
2312019
Pax5 determines the identity of B cells from the beginning to the end of B-lymphopoiesis
SL Nutt, D Eberhard, M Horcher, AG Rolink, M Busslinger
International reviews of immunology 20 (1), 65-82, 2001
1602001
The N‐terminal domain of the human TATA‐binding protein plays a role in transcription from TATA‐containing RNA polymerase II and III promoters.
A Lescure, Y Lutz, D Eberhard, X Jacq, A Krol, I Grummt, I Davidson, ...
The EMBO journal 13 (5), 1166-1175, 1994
1421994
A TBP-containing multiprotein complex (TIF-IB) mediates transcription specificity of murine RNA polymerase I
D Eberhard, L Tora, JM Egly, I Grummt
Nucleic acids research 21 (18), 4180-4186, 1993
1191993
The partial homeodomain of the transcription factor Pax-5 (BSAP) is an interaction motif for the retinoblastoma and TATA-binding proteins
D Eberhard, M Busslinger
Cancer research 59 (7_Supplement), 1716s-1725s, 1999
1051999
Chemoproteomics-based kinome profiling and target deconvolution of clinical multi-kinase inhibitors in primary chronic lymphocytic leukemia cells
U Kruse, CP Pallasch, M Bantscheff, D Eberhard, L Frenzel, S Ghidelli, ...
Leukemia 25 (1), 89-100, 2011
872011
Corecruitment of the Grg4 repressor by PU. 1 is critical for Pax5‐mediated repression of B‐cell‐specific genes
Y Linderson, D Eberhard, S Malin, A Johansson, M Busslinger, ...
EMBO reports 5 (3), 291-296, 2004
822004
TBP‐associated factors interact with DNA and govern species specificity of RNA polymerase I transcription.
U Rudloff, D Eberhard, L Tora, H Stunnenberg, I Grummt
The EMBO Journal 13 (11), 2611-2616, 1994
781994
Chemical Proteomic Analysis Reveals the Drugability of the Kinome of Trypanosoma brucei
MD Urbaniak, T Mathieson, M Bantscheff, D Eberhard, R Grimaldi, ...
ACS chemical biology 7 (11), 1858-1865, 2012
622012
Gbx2 and Otx2 interact with the WD40 domain of Groucho/Tle corepressors
T Heimbucher, C Murko, B Bajoghli, N Aghaallaei, A Huber, R Stebegg, ...
Molecular and cellular biology 27 (1), 340-351, 2007
542007
Interrogating the druggability of the 2-oxoglutarate-dependent dioxygenase target class by chemical proteomics
G Joberty, M Boesche, JA Brown, D Eberhard, NS Garton, PG Humphreys, ...
ACS chemical biology 11 (7), 2002-2010, 2016
402016
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