| Angiogenesis inhibitors: current strategies and future prospects KM Cook, WD Figg CA: a cancer journal for clinicians 60 (4), 222-243, 2010 | 640 | 2010 |
| Asparaginyl hydroxylation of the Notch ankyrin repeat domain by factor inhibiting hypoxia-inducible factor ML Coleman, MA McDonough, KS Hewitson, C Coles, J Mecinovicí, ... Journal of Biological Chemistry 282 (33), 24027-24038, 2007 | 256 | 2007 |
| Epidithiodiketopiperazines block the interaction between hypoxia-inducible factor-1α (HIF-1α) and p300 by a zinc ejection mechanism KM Cook, ST Hilton, J Mecinović, WB Motherwell, WD Figg, CJ Schofield Journal of biological chemistry 284 (39), 26831-26838, 2009 | 197 | 2009 |
| Post-translational control of protein function by disulfide bond cleavage KM Cook, PJ Hogg Antioxidants & redox signaling 18 (15), 1987-2015, 2013 | 138 | 2013 |
| Models of intermittent hypoxia and obstructive sleep apnea: molecular pathways and their contribution to cancer I Hunyor, KM Cook American Journal of Physiology-Regulatory, Integrative and Comparative …, 2018 | 129 | 2018 |
| A substrate-driven allosteric switch that enhances PDI catalytic activity RH Bekendam, PK Bendapudi, L Lin, PP Nag, J Pu, DR Kennedy, ... Nature communications 7 (1), 12579, 2016 | 119 | 2016 |
| Angiogenesis: an integrative approach from science to medicine WD Figg, J Folkman Springer Science & Business Media, 2008 | 113 | 2008 |
| Control of blood proteins by functional disulfide bonds D Butera, KM Cook, J Chiu, JWH Wong, PJ Hogg Blood, The Journal of the American Society of Hematology 123 (13), 2000-2007, 2014 | 109 | 2014 |
| Epidithiodiketopiperazines (ETPs) exhibit in vitro antiangiogenic and in vivo antitumor activity by disrupting the HIF-1α/p300 complex in a preclinical model of prostate cancer KM Reece, ED Richardson, KM Cook, TJ Campbell, ST Pisle, AJ Holly, ... Molecular Cancer 13, 1-12, 2014 | 97 | 2014 |
| Autoregulation of von Willebrand factor function by a disulfide bond switch D Butera, F Passam, L Ju, KM Cook, H Woon, C Aponte-Santamaría, ... Science advances 4 (2), eaaq1477, 2018 | 93 | 2018 |
| Zinc is a potent and specific inhibitor of IFN-λ3 signalling SA Read, KS O’Connor, V Suppiah, CLE Ahlenstiel, S Obeid, KM Cook, ... Nature communications 8 (1), 15245, 2017 | 64 | 2017 |
| Screening and biological effects of marine pyrroloiminoquinone alkaloids: Potential inhibitors of the HIF-1α/p300 interaction AKL Goey, CH Chau, TM Sissung, KM Cook, DJ Venzon, A Castro, ... Journal of natural products 79 (5), 1267-1275, 2016 | 63 | 2016 |
| Obstructive sleep apnea activates HIF-1 in a hypoxia dose-dependent manner in HCT116 colorectal carcinoma cells CA Martinez, B Kerr, C Jin, PA Cistulli, KM Cook International journal of molecular sciences 20 (2), 445, 2019 | 59 | 2019 |
| Synthesis and cytotoxicity of novel sansalvamide A derivatives CL Carroll, JVC Johnston, A Kekec, JD Brown, E Parry, J Cajica, I Medina, ... Organic letters 7 (16), 3481-3484, 2005 | 51 | 2005 |
| Structural elucidation and synthesis of eudistidine A: an unusual polycyclic marine alkaloid that blocks interaction of the protein binding domains of p300 and HIF-1α STS Chan, PR Patel, TR Ransom, CJ Henrich, TC McKee, AKL Goey, ... Journal of the American Chemical Society 137 (16), 5569-5575, 2015 | 45 | 2015 |
| Inhibition of the HIF1α-p300 interaction by quinone-and indandione-mediated ejection of structural Zn (II) MKP Jayatunga, S Thompson, TC McKee, MC Chan, KM Reece, ... European journal of medicinal chemistry 94, 509-516, 2015 | 44 | 2015 |
| Out of breath, out of time: interactions between HIF and circadian rhythms EJ O’Connell, CA Martinez, YG Liang, PA Cistulli, KM Cook American Journal of Physiology-Cell Physiology 319 (3), C533-C540, 2020 | 39 | 2020 |
| Hypoxia, metabolism, and the circadian clock: new links to overcome radiation resistance in high-grade gliomas H Shen, K Cook, HE Gee, E Hau Journal of Experimental & Clinical Cancer Research 39, 2020 | 38 | 2020 |
| C-terminal HSP90 inhibitors block the HIF-1 hypoxic response by degrading HIF-1α through the oxygen-dependent degradation pathway N Kataria, CA Martinez, B Kerr, SS Zaiter, M Morgan, SR McAlpine, ... Cell Physiol Biochem 53 (3), 480-495, 2019 | 38 | 2019 |
| Targeting glucose metabolism of cancer cells with dichloroacetate to radiosensitize high-grade gliomas KM Cook, H Shen, KJ McKelvey, HE Gee, E Hau International Journal of Molecular Sciences 22 (14), 7265, 2021 | 37 | 2021 |
William Douglas Figg, SrNational Cancer InstituteVerified email at mail.nih.gov
