Justin Chen
Justin Chen
Senior Scientist | Omega Therapeutics
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Narcolepsy is strongly associated with the T-cell receptor alpha locus
J Hallmayer, J Faraco, L Lin, S Hesselson, J Winkelmann, M Kawashima, ...
Nature genetics 41 (6), 708-711, 2009
Association of common genetic variation in the insulin/IGF1 signaling pathway with human longevity
L Pawlikowska, D Hu, S Huntsman, A Sung, C Chu, J Chen, AH Joyner, ...
Aging cell 8 (4), 460-472, 2009
Alternative splicing in cancer: implications for biology and therapy
J Chen, WA Weiss
Oncogene 34 (1), 1-14, 2015
EGFR Phosphorylates Tumor-Derived EGFRvIII Driving STAT3/5 and Progression in Glioblastoma
QW Fan, CK Cheng, WC Gustafson, E Charron, P Zipper, RA Wong, ...
Cancer Cell 24 (4), 438-449, 2013
Drugging MYCN through an Allosteric Transition in Aurora Kinase A
WC Gustafson, JG Meyerowitz, EA Nekritz, J Chen, C Benes, E Charron, ...
Cancer cell 26 (3), 414-427, 2014
Distinct neural stem cell populations give rise to disparate brain tumors in response to N-MYC
FJ Swartling, V Savov, AI Persson, J Chen, CS Hackett, PA Northcott, ...
Cancer cell 21 (5), 601-613, 2012
Reversing HOXA9 oncogene activation by PI3K inhibition: epigenetic mechanism and prognostic significance in human glioblastoma
BM Costa, JS Smith, Y Chen, J Chen, HS Phillips, KD Aldape, G Zardo, ...
Cancer research 70 (2), 453-462, 2010
Green technologies for room temperature nucleic acid storage
E Wan, M Akana, J Pons, J Chen, S Musone, PY Kwok, W Liao
Current issues in molecular biology 12 (3), 135, 2010
Voltage-gated potassium channel EAG2 controls mitotic entry and tumor growth in medulloblastoma via regulating cell volume dynamics
X Huang, AM Dubuc, R Hashizume, J Berg, Y He, J Wang, C Chiang, ...
Genes & Development 26 (16), 1780-1796, 2012
Differences in allergic sensitization by self-reported race and genetic ancestry
JJ Yang, EG Burchard, S Choudhry, CC Johnson, DR Ownby, D Favro, ...
Journal of Allergy and Clinical Immunology 122 (4), 820-827. e9, 2008
Natural variation in four human collagen genes across an ethnically diverse population
TF Chan, A Poon, A Basu, NR Addleman, J Chen, A Phong, PH Byers, ...
Genomics 91 (4), 307-314, 2008
Engineering Genetic Predisposition in Human Neuroepithelial Stem Cells Recapitulates Medulloblastoma Tumorigenesis
M Huang, J Tailor, Q Zhen, AH Gillmor, ML Miller, H Weishaupt, J Chen, ...
Cell Stem Cell 25, 433-446, 2019
Multi-faceted epigenetic dysregulation of gene expression promotes esophageal squamous cell carcinoma
W Cao, H Lee, W Wu, A Zaman, S McCorkle, M Yan, J Chen, Q Xing, ...
Nature Communications 11 (1), 1-19, 2020
A maternally inherited chromosome 18q22. 1 deletion in a male with late‐presenting diaphragmatic hernia and microphthalmia–evaluation of DSEL as a candidate gene for the …
H Zayed, R Chao, A Moshrefi, N LopezJimenez, A Delaney, J Chen, ...
American Journal of Medical Genetics Part A 152 (4), 916-923, 2010
Poly (ADP-Ribose) Polymerase Inhibitor MK-4827 together with Radiation as a Novel Therapy for Metastatic Neuroblastoma
S Mueller, S Bhargava, AM Molinaro, X Yang, I Kolkowitz, A Olow, ...
Anticancer research 33 (3), 755-762, 2013
HAT1 coordinates histone production and acetylation via H4 promoter binding
JJ Gruber, B Geller, AM Lipchik, J Chen, AA Salahudeen, AN Ram, ...
Molecular cell 75 (4), 711-724. e5, 2019
The genetics of splicing in neuroblastoma
J Chen, CS Hackett, S Zhang, YK Song, RJA Bell, AM Molinaro, ...
Cancer discovery 5 (4), 380-395, 2015
Expression Quantitative Trait Loci and Receptor Pharmacology Implicate Arg1 and the GABA-A Receptor as Therapeutic Targets in Neuroblastoma
CS Hackett, DA Quigley, RA Wong, J Chen, C Cheng, YK Song, JS Wei, ...
Cell reports 9 (3), 1034-1046, 2014
High-Resolution Bisulfite-Sequencing of Peripheral Blood DNA Methylation in Early-Onset and Familial Risk Breast Cancer Patients
J Chen, MK Haanpää, JJ Gruber, N Jäger, JM Ford, MP Snyder
Clinical Cancer Research 25, 5301-5314, 2019
When Deletions Gain Functions: Commandeering Epigenetic Mechanisms
J Chen, WA Weiss
Cancer Cell 26 (2), 160-161, 2014
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