Suppressing fatty acid uptake has therapeutic effects in preclinical models of prostate cancer MJ Watt, AK Clark, LA Selth, VR Haynes, N Lister, R Rebello, LH Porter, ... Science translational medicine 11 (478), eaau5758, 2019 | 295 | 2019 |
LFQ-analyst: an easy-to-use interactive web platform to analyze and visualize label-free proteomics data preprocessed with MaxQuant AD Shah, RJA Goode, C Huang, DR Powell, RB Schittenhelm Journal of proteome research 19 (1), 204-211, 2019 | 180 | 2019 |
Biochemical membrane lipidomics during Drosophila development XL Guan, G Cestra, G Shui, A Kuhrs, RB Schittenhelm, E Hafen, ... Developmental cell 24 (1), 98-111, 2013 | 168 | 2013 |
Comprehensive characterization of distinct states of human naive pluripotency generated by reprogramming X Liu, CM Nefzger, FJ Rossello, J Chen, AS Knaupp, J Firas, E Ford, ... Nature methods 14 (11), 1055-1062, 2017 | 166 | 2017 |
Atmospheric carbon monoxide oxidation is a widespread mechanism supporting microbial survival PRF Cordero, K Bayly, P Man Leung, C Huang, ZF Islam, ... The ISME journal 13 (11), 2868-2881, 2019 | 164 | 2019 |
Mitochondrial dysfunction caused by outer membrane vesicles from Gram-negative bacteria activates intrinsic apoptosis and inflammation P Deo, SH Chow, ML Han, M Speir, C Huang, RB Schittenhelm, S Dhital, ... Nature microbiology 5 (11), 1418-1427, 2020 | 154 | 2020 |
Revisiting the arthritogenic peptide theory: quantitative not qualitative changes in the peptide repertoire of HLA–B27 allotypes RB Schittenhelm, TCCLK Sian, PG Wilmann, NL Dudek, AW Purcell Arthritis & rheumatology 67 (3), 702-713, 2015 | 145 | 2015 |
Identification of metabolically distinct adipocyte progenitor cells in human adipose tissues A Raajendiran, G Ooi, J Bayliss, PE O’Brien, RB Schittenhelm, AK Clark, ... Cell reports 27 (5), 1528-1540. e7, 2019 | 137 | 2019 |
An open-source computational and data resource to analyze digital maps of immunopeptidomes E Caron, L Espona, DJ Kowalewski, H Schuster, N Ternette, A Alpízar, ... Elife 4, e07661, 2015 | 132 | 2015 |
Genetic interactions of separase regulatory subunits reveal the diverged Drosophila Cenp-C homolog S Heeger, O Leismann, R Schittenhelm, O Schraidt, S Heidmann, ... Genes & development 19 (17), 2041-2053, 2005 | 127 | 2005 |
Spatial organization of a ubiquitous eukaryotic kinetochore protein network in Drosophila chromosomes RB Schittenhelm, S Heeger, F Althoff, A Walter, S Heidmann, K Mechtler, ... Chromosoma 116, 385-402, 2007 | 123 | 2007 |
RNA exploits an exposed regulatory site to inhibit the enzymatic activity of PRC2 Q Zhang, NJ McKenzie, R Warneford-Thomson, EH Gail, SF Flanigan, ... Nature structural & molecular biology 26 (3), 237-247, 2019 | 107 | 2019 |
Detrimental incorporation of excess Cenp-A/Cid and Cenp-C into Drosophila centromeres is prevented by limiting amounts of the bridging factor Cal1 RB Schittenhelm, F Althoff, S Heidmann, CF Lehner Journal of cell science 123 (21), 3768-3779, 2010 | 106 | 2010 |
Restriction of essential amino acids dictates the systemic metabolic response to dietary protein dilution YW Yap, PM Rusu, AY Chan, BC Fam, A Jungmann, SM Solon-Biet, ... Nature communications 11 (1), 2894, 2020 | 88 | 2020 |
Intrakinetochore localization and essential functional domains of Drosophila Spc105 RB Schittenhelm, R Chaleckis, CF Lehner The EMBO journal 28 (16), 2374-2386, 2009 | 80 | 2009 |
Modularity and hormone sensitivity of the Drosophila melanogaster insulin receptor/target of rapamycin interaction proteome T Glatter, RB Schittenhelm, O Rinner, K Roguska, A Wepf, MA Jünger, ... Molecular systems biology 7 (1), 547, 2011 | 71 | 2011 |
Structures of a non-ribosomal peptide synthetase condensation domain suggest the basis of substrate selectivity T Izoré, YT Candace Ho, JA Kaczmarski, A Gavriilidou, KH Chow, ... Nature communications 12 (1), 2511, 2021 | 69 | 2021 |
Identification of novel Acinetobacter baumannii type VI secretion system antibacterial effector and immunity pairs TC Fitzsimons, JM Lewis, A Wright, O Kleifeld, RB Schittenhelm, D Powell, ... Infection and immunity 86 (8), 10.1128/iai. 00297-18, 2018 | 66 | 2018 |
A natural peptide antigen within the plasmodium ribosomal protein RPL6 confers liver TRM cell-mediated immunity against malaria in mice AM Valencia-Hernandez, WY Ng, N Ghazanfari, S Ghilas, ... Cell host & microbe 27 (6), 950-962. e7, 2020 | 64 | 2020 |
Halogenation of glycopeptide antibiotics occurs at the amino acid level during non-ribosomal peptide synthesis T Kittilä, C Kittel, J Tailhades, D Butz, M Schoppet, A Büttner, RJA Goode, ... Chemical Science 8 (9), 5992-6004, 2017 | 63 | 2017 |