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Ralf Schittenhelm
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Suppressing fatty acid uptake has therapeutic effects in preclinical models of prostate cancer
MJ Watt, AK Clark, LA Selth, VR Haynes, N Lister, R Rebello, LH Porter, ...
Science translational medicine 11 (478), eaau5758, 2019
2952019
LFQ-analyst: an easy-to-use interactive web platform to analyze and visualize label-free proteomics data preprocessed with MaxQuant
AD Shah, RJA Goode, C Huang, DR Powell, RB Schittenhelm
Journal of proteome research 19 (1), 204-211, 2019
1802019
Biochemical membrane lipidomics during Drosophila development
XL Guan, G Cestra, G Shui, A Kuhrs, RB Schittenhelm, E Hafen, ...
Developmental cell 24 (1), 98-111, 2013
1682013
Comprehensive characterization of distinct states of human naive pluripotency generated by reprogramming
X Liu, CM Nefzger, FJ Rossello, J Chen, AS Knaupp, J Firas, E Ford, ...
Nature methods 14 (11), 1055-1062, 2017
1662017
Atmospheric carbon monoxide oxidation is a widespread mechanism supporting microbial survival
PRF Cordero, K Bayly, P Man Leung, C Huang, ZF Islam, ...
The ISME journal 13 (11), 2868-2881, 2019
1642019
Mitochondrial dysfunction caused by outer membrane vesicles from Gram-negative bacteria activates intrinsic apoptosis and inflammation
P Deo, SH Chow, ML Han, M Speir, C Huang, RB Schittenhelm, S Dhital, ...
Nature microbiology 5 (11), 1418-1427, 2020
1542020
Revisiting the arthritogenic peptide theory: quantitative not qualitative changes in the peptide repertoire of HLA–B27 allotypes
RB Schittenhelm, TCCLK Sian, PG Wilmann, NL Dudek, AW Purcell
Arthritis & rheumatology 67 (3), 702-713, 2015
1452015
Identification of metabolically distinct adipocyte progenitor cells in human adipose tissues
A Raajendiran, G Ooi, J Bayliss, PE O’Brien, RB Schittenhelm, AK Clark, ...
Cell reports 27 (5), 1528-1540. e7, 2019
1372019
An open-source computational and data resource to analyze digital maps of immunopeptidomes
E Caron, L Espona, DJ Kowalewski, H Schuster, N Ternette, A Alpízar, ...
Elife 4, e07661, 2015
1322015
Genetic interactions of separase regulatory subunits reveal the diverged Drosophila Cenp-C homolog
S Heeger, O Leismann, R Schittenhelm, O Schraidt, S Heidmann, ...
Genes & development 19 (17), 2041-2053, 2005
1272005
Spatial organization of a ubiquitous eukaryotic kinetochore protein network in Drosophila chromosomes
RB Schittenhelm, S Heeger, F Althoff, A Walter, S Heidmann, K Mechtler, ...
Chromosoma 116, 385-402, 2007
1232007
RNA exploits an exposed regulatory site to inhibit the enzymatic activity of PRC2
Q Zhang, NJ McKenzie, R Warneford-Thomson, EH Gail, SF Flanigan, ...
Nature structural & molecular biology 26 (3), 237-247, 2019
1072019
Detrimental incorporation of excess Cenp-A/Cid and Cenp-C into Drosophila centromeres is prevented by limiting amounts of the bridging factor Cal1
RB Schittenhelm, F Althoff, S Heidmann, CF Lehner
Journal of cell science 123 (21), 3768-3779, 2010
1062010
Restriction of essential amino acids dictates the systemic metabolic response to dietary protein dilution
YW Yap, PM Rusu, AY Chan, BC Fam, A Jungmann, SM Solon-Biet, ...
Nature communications 11 (1), 2894, 2020
882020
Intrakinetochore localization and essential functional domains of Drosophila Spc105
RB Schittenhelm, R Chaleckis, CF Lehner
The EMBO journal 28 (16), 2374-2386, 2009
802009
Modularity and hormone sensitivity of the Drosophila melanogaster insulin receptor/target of rapamycin interaction proteome
T Glatter, RB Schittenhelm, O Rinner, K Roguska, A Wepf, MA Jünger, ...
Molecular systems biology 7 (1), 547, 2011
712011
Structures of a non-ribosomal peptide synthetase condensation domain suggest the basis of substrate selectivity
T Izoré, YT Candace Ho, JA Kaczmarski, A Gavriilidou, KH Chow, ...
Nature communications 12 (1), 2511, 2021
692021
Identification of novel Acinetobacter baumannii type VI secretion system antibacterial effector and immunity pairs
TC Fitzsimons, JM Lewis, A Wright, O Kleifeld, RB Schittenhelm, D Powell, ...
Infection and immunity 86 (8), 10.1128/iai. 00297-18, 2018
662018
A natural peptide antigen within the plasmodium ribosomal protein RPL6 confers liver TRM cell-mediated immunity against malaria in mice
AM Valencia-Hernandez, WY Ng, N Ghazanfari, S Ghilas, ...
Cell host & microbe 27 (6), 950-962. e7, 2020
642020
Halogenation of glycopeptide antibiotics occurs at the amino acid level during non-ribosomal peptide synthesis
T Kittilä, C Kittel, J Tailhades, D Butz, M Schoppet, A Büttner, RJA Goode, ...
Chemical Science 8 (9), 5992-6004, 2017
632017
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