Gerard Drewes
Gerard Drewes
Cellzome/GlaxoSmithKline R&D
Verified email at
Cited by
Cited by
Functional organization of the yeast proteome by systematic analysis of protein complexes
AC Gavin, M Bösche, R Krause, P Grandi, M Marzioch, A Bauer, J Schultz, ...
Nature 415 (6868), 141-147, 2002
Proteome survey reveals modularity of the yeast cell machinery
AC Gavin, P Aloy, P Grandi, R Krause, M Boesche, M Marzioch, C Rau, ...
Nature 440 (7084), 631-636, 2006
Inhibition of BET recruitment to chromatin as an effective treatment for MLL-fusion leukaemia
MA Dawson, RK Prinjha, A Dittmann, G Giotopoulos, M Bantscheff, ...
Nature 478 (7370), 529-533, 2011
A physical and functional map of the human TNF-α/NF-κB signal transduction pathway
T Bouwmeester, A Bauch, H Ruffner, PO Angrand, G Bergamini, ...
Nature cell biology 6 (2), 97-105, 2004
Quantitative chemical proteomics reveals mechanisms of action of clinical ABL kinase inhibitors
M Bantscheff, D Eberhard, Y Abraham, S Bastuck, M Boesche, S Hobson, ...
Nature biotechnology 25 (9), 1035-1044, 2007
MARK, a novel family of protein kinases that phosphorylate microtubule-associated proteins and trigger microtubule disruption
G Drewes, A Ebneth, U Preuss, EM Mandelkow, E Mandelkow
Cell 89 (2), 297-308, 1997
Tracking cancer drugs in living cells by thermal profiling of the proteome
MM Savitski, FBM Reinhard, H Franken, T Werner, MF Savitski, ...
Science 346 (6205), 1255784, 2014
Phosphorylation of Ser262 strongly reduces binding of tau to microtubules: distinction between PHF-like immunoreactivity and microtubule binding
J Biernat, N Gustke, G Drewes, E Mandelkow
Neuron 11 (1), 153-163, 1993
A selective jumonji H3K27 demethylase inhibitor modulates the proinflammatory macrophage response
L Kruidenier, C Chung, Z Cheng, J Liddle, KH Che, G Joberty, ...
Nature 488 (7411), 404-408, 2012
Chemoproteomics profiling of HDAC inhibitors reveals selective targeting of HDAC complexes
M Bantscheff, C Hopf, MM Savitski, A Dittmann, P Grandi, AM Michon, ...
Nature biotechnology 29 (3), 255-265, 2011
Mitogen activated protein (MAP) kinase transforms tau protein into an Alzheimer‐like state.
G Drewes, B Lichtenberg‐Kraag, F Döring, EM Mandelkow, J Biernat, ...
The EMBO journal 11 (6), 2131-2138, 1992
Glycogen synthase kinase‐3 and the Alzheimer‐like state of microtubule‐associated protein tau
EM Mandelkow, G Drewes, J Biernat, N Gustke, J Van Lint, ...
FEBS letters 314 (3), 315-321, 1992
Inhibition of PAD4 activity is sufficient to disrupt mouse and human NET formation
HD Lewis, J Liddle, JE Coote, SJ Atkinson, MD Barker, BD Bax, KL Bicker, ...
Nature chemical biology 11 (3), 189-191, 2015
Alzheimer-like paired helical filaments and antiparallel dimers formed from microtubule-associated protein tau in vitro.
H Wille, G Drewes, J Biernat, EM Mandelkow, E Mandelkow
The Journal of cell biology 118 (3), 573-584, 1992
Thermal proteome profiling for unbiased identification of direct and indirect drug targets using multiplexed quantitative mass spectrometry
H Franken, T Mathieson, D Childs, GMA Sweetman, T Werner, I Tögel, ...
Nature protocols 10 (10), 1567-1593, 2015
The International Human Epigenome Consortium: a blueprint for scientific collaboration and discovery
HG Stunnenberg, S Abrignani, D Adams, M de Almeida, L Altucci, V Amin, ...
Cell 167 (5), 1145-1149, 2016
Microtubule-associated protein/microtubule affinity-regulating kinase (p110mark): a novel protein kinase that regulates tau-microtubule interactions and dynamic instability by …
HE Meyer, EM Mandelkow, G Drewes, B Trinczek, S Illenberger, J Biernat, ...
Journal of Biological Chemistry 270 (13), 7679-7688, 1995
MAPs, MARKs and microtubule dynamics
G Drewes, A Ebneth, EM Mandelkow
Trends in biochemical sciences 23 (8), 307-311, 1998
Increased expression of BIN1 mediates Alzheimer genetic risk by modulating tau pathology
J Chapuis, F Hansmannel, M Gistelinck, A Mounier, ...
Molecular psychiatry 18 (11), 1225-1234, 2013
Tau domains, phosphorylation, and interactions with microtubules
EM Mandelkow, J Biernat, G Drewes, N Gustke, B Trinczek, E Mandelkow
Neurobiology of aging 16 (3), 355-362, 1995
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