| Oncogenesis following delivery of a nonprimate lentiviral gene therapy vector to fetal and neonatal mice M Themis, SN Waddington, M Schmidt, C Von Kalle, Y Wang, F Al-Allaf, ... Molecular Therapy 12 (4), 763-771, 2005 | 272 | 2005 |
| Widespread Distribution and Muscle Differentiation of Human Fetal Mesenchymal Stem Cells After Intrauterine Transplantation in Dystrophic mdx Mouse J Chan, SN Waddington, K O'Donoghue, H Kurata, PV Guillot, ... Stem cells 25 (4), 875-884, 2007 | 148 | 2007 |
| Restoration of LDL receptor function in cells from patients with autosomal recessive hypercholesterolemia by retroviral expression of ARH1 ER Eden, DD Patel, XM Sun, JJ Burden, M Themis, M Edwards, P Lee, ... The Journal of clinical investigation 110 (11), 1695-1702, 2002 | 98 | 2002 |
| Successful expression of β-galactosidase and factor IX transgenes in fetal and neonatal sheep after ultrasound-guided percutaneous adenovirus vector administration into the … M Themis, H Schneider, T Kiserud, T Cook, S Adebakin, S Jezzard, ... Gene Therapy 6 (7), 1239-1248, 1999 | 91 | 1999 |
| Foetal gene delivery in mice by intra-amniotic administration of retroviral producer cells and adenovirus AM Douar, S Adebakin, M Themis, A Pavirani, T Cook, C Coutelle Gene Therapy 4 (9), 883-890, 1997 | 90 | 1997 |
| Differentiation of human fetal mesenchymal stem cells into cells with an oligodendrocyte phenotype NL Kennea, SN Waddington, J Chan, K O’Donoghue, D Yeung, DL Taylor, ... Cell Cycle 8 (7), 1069-1079, 2009 | 85 | 2009 |
| Long-term transgene expression by administration of a lentivirus-based vector to the fetal circulation of immuno-competent mice SN Waddington, KA Mitrophanous, FM Ellard, SMK Buckley, M Nivsarkar, ... Gene therapy 10 (15), 1234-1240, 2003 | 83 | 2003 |
| LDLR-Gene therapy for familial hypercholesterolaemia: problems, progress, and perspectives FA Al-Allaf, C Coutelle, SN Waddington, AL David, R Harbottle, M Themis International archives of medicine 3 (1), 36, 2010 | 80 | 2010 |
| Three-dimensional cell culture: from evolution to revolution S Alhaque, M Themis, H Rashidi Philosophical Transactions of the Royal Society B: Biological Sciences 373 …, 2018 | 78 | 2018 |
| Enhancement of adenovirus-mediated gene transfer to the airways by DEAE dextran and sodium caprate in vivo LG Gregory, RP Harbottle, L Lawrence, HJ Knapton, M Themis, ... Molecular therapy 7 (1), 19-26, 2003 | 74 | 2003 |
| Permanent partial phenotypic correction and tolerance in a mouse model of hemophilia B by stem cell gene delivery of human factor IX BW Bigger, EK Siapati, A Mistry, SN Waddington, MS Nivsarkar, L Jacobs, ... Gene therapy 13 (2), 117-126, 2006 | 66 | 2006 |
| In utero gene therapy: current challenges and perspectives SN Waddington, MG Kramer, R Hernandez-Alcoceba, SMK Buckley, ... Molecular Therapy 11 (5), 661-676, 2005 | 65 | 2005 |
| Fetal and neonatal gene therapy: benefits and pitfalls SN Waddington, NL Kennea, SMK Buckley, LG Gregory, M Themis, ... Gene therapy 11 (1), S92-S97, 2004 | 53 | 2004 |
| Therapeutic plasma concentrations of human factor IX in mice after gene delivery into the amniotic cavity: a model for the prenatal treatment of haemophilia B H Schneider, S Adebakin, M Themis, T Cook, AM Douar, A Pavirani, ... The Journal of Gene Medicine: A cross‐disciplinary journal for research on …, 1999 | 53 | 1999 |
| Highly efficient EIAV-mediated in utero gene transfer and expression in the major muscle groups affected by Duchenne muscular dystrophy LG Gregory, SN Waddington, MV Holder, KA Mitrophanous, SMK Buckley, ... Gene therapy 11 (14), 1117-1125, 2004 | 49 | 2004 |
| Overexpression of connexin 43 using a retroviral vector improves electrical coupling of skeletal myoblasts with cardiac myocytes in vitro O Tolmachov, YL Ma, M Themis, P Patel, H Spohr, KT MacLeod, ... BMC cardiovascular disorders 6, 1-11, 2006 | 46 | 2006 |
| Retargeting of adenoviral vectors to neurons using the Hc fragment of tetanus toxin H Schneider, M Groves, C Mühle, PN Reynolds, A Knight, M Themis, ... Gene therapy 7 (18), 1584-1592, 2000 | 46 | 2000 |
| Combinations and methods for promoting in vivo liver cell proliferation and enhancing in vivo liver-directed gene transduction MR Alison, C Coutelle, SJ Forbes, HJF Hodgson, I Sarosi, M Themis US Patent 6,790,838, 2004 | 42 | 2004 |
| A novel splice variant of the DNA-PKcs gene is associated with clinical and cellular radiosensitivity in a patient with xeroderma pigmentosum F Abbaszadeh, PH Clingen, CF Arlett, PN Plowman, EC Bourton, ... Journal of medical genetics 47 (3), 176-181, 2010 | 41 | 2010 |
| Transgenic organism P Radcliffe, K Mitrophanous, M Themis US Patent App. 12/014,057, 2009 | 41 | 2009 |
