Consistent success in life-supporting porcine cardiac xenotransplantation M Längin, T Mayr, B Reichart, S Michel, S Buchholz, S Guethoff, ... Nature 564 (7736), 430-433, 2018 | 491 | 2018 |
Inhibition of microRNA-92a protects against ischemia/reperfusion injury in a large-animal model R Hinkel, D Penzkofer, S Zühlke, A Fischer, W Husada, QF Xu, E Baloch, ... Circulation 128 (10), 1066-1075, 2013 | 402 | 2013 |
Cardiac AAV9-S100A1 gene therapy rescues post-ischemic heart failure in a preclinical large animal model ST Pleger, C Shan, J Ksienzyk, R Bekeredjian, P Boekstegers, R Hinkel, ... Science translational medicine 3 (92), 92ra64-92ra64, 2011 | 253 | 2011 |
Angiopoietin 2 mediates microvascular and hemodynamic alterations in sepsis T Ziegler, J Horstkotte, C Schwab, V Pfetsch, K Weinmann, S Dietzel, ... The Journal of clinical investigation 123 (8), 3436-3445, 2013 | 214 | 2013 |
Thymosin β4 is an essential paracrine factor of embryonic endothelial progenitor cell–mediated cardioprotection R Hinkel, C El-Aouni, T Olson, J Horstkotte, S Mayer, S Müller, ... Circulation 117 (17), 2232-2240, 2008 | 203 | 2008 |
Transgenic expression of the human A20 gene in cloned pigs provides protection against apoptotic and inflammatory stimuli M Oropeza, B Petersen, JW Carnwath, A Lucas‐Hahn, E Lemme, ... Xenotransplantation 16 (6), 522-534, 2009 | 163 | 2009 |
Diabetes mellitus–induced microvascular destabilization in the myocardium R Hinkel, A Howe, S Renner, J Ng, S Lee, K Klett, V Kaczmarek, A Moretti, ... Journal of the American College of Cardiology 69 (2), 131-143, 2017 | 161 | 2017 |
Pro-angiogenic macrophage phenotype to promote myocardial repair B Ferraro, G Leoni, R Hinkel, S Ormanns, N Paulin, A Ortega-Gomez, ... Journal of the American College of Cardiology 73 (23), 2990-3002, 2019 | 159 | 2019 |
Regulation of monocyte cell fate by blood vessels mediated by Notch signalling J Gamrekelashvili, R Giagnorio, J Jussofie, O Soehnlein, J Duchene, ... Nature communications 7 (1), 12597, 2016 | 154 | 2016 |
Annexin A1 counteracts chemokine-induced arterial myeloid cell recruitment M Drechsler, R de Jong, J Rossaint, JR Viola, G Leoni, JM Wang, ... Circulation research 116 (5), 827-835, 2015 | 149 | 2015 |
Heat shock protein 90 transfection reduces ischemia-reperfusion–induced myocardial dysfunction via reciprocal endothelial NO synthase serine 1177 phosphorylation and threonine … C Kupatt, C Dessy, R Hinkel, P Raake, G Daneau, C Bouzin, ... Arteriosclerosis, thrombosis, and vascular biology 24 (8), 1435-1441, 2004 | 147 | 2004 |
AntimiR-21 prevents myocardial dysfunction in a pig model of ischemia/reperfusion injury R Hinkel, D Ramanujam, V Kaczmarek, A Howe, K Klett, C Beck, A Dueck, ... Journal of the American College of Cardiology 75 (15), 1788-1800, 2020 | 138 | 2020 |
Recruitment of classical monocytes can be inhibited by disturbing heteromers of neutrophil HNP1 and platelet CCL5 JE Alard, A Ortega-Gomez, K Wichapong, D Bongiovanni, M Horckmans, ... Science translational medicine 7 (317), 317ra196-317ra196, 2015 | 129 | 2015 |
Myocardial gene transfer by selective pressure-regulated retroinfusion of coronary veins: comparison with surgical and percutaneous intramyocardial gene delivery P Raake, G von Degenfeld, R Hinkel, R Vachenauer, T Sandner, S Beller, ... Journal of the American College of Cardiology 44 (5), 1124-1129, 2004 | 126 | 2004 |
Cardio-specific long-term gene expression in a porcine model after selective pressure-regulated retroinfusion of adeno-associated viral (AAV) vectors PW Raake, R Hinkel, S Müller, S Delker, R Kreuzpointner, C Kupatt, ... Gene Therapy 15 (1), 12-17, 2008 | 111 | 2008 |
Accuracy of dynamic computed tomography adenosine stress myocardial perfusion imaging in estimating myocardial blood flow at various degrees of coronary artery stenosis using a … F Bamberg, R Hinkel, F Schwarz, TA Sandner, E Baloch, R Marcus, ... Investigative radiology 47 (1), 71-77, 2012 | 108 | 2012 |
Cotransfection of vascular endothelial growth factor-A and platelet-derived growth factor-B via recombinant adeno-associated virus resolves chronic ischemic malperfusion: role … C Kupatt, R Hinkel, A Pfosser, C El-Aouni, A Wuchrer, A Fritz, F Globisch, ... Journal of the American College of Cardiology 56 (5), 414-422, 2010 | 107 | 2010 |
Retroinfusion of embryonic endothelial progenitor cells attenuates ischemia-reperfusion injury in pigs: role of phosphatidylinositol 3-kinase/AKT kinase C Kupatt, R Hinkel, M Lamparter, ML von Brühl, T Pohl, J Horstkotte, ... Circulation 112 (9_supplement), I-117-I-122, 2005 | 107 | 2005 |
Subtype-specific promoter-driven action potential imaging for precise disease modelling and drug testing in hiPSC-derived cardiomyocytes Z Chen, W Xian, M Bellin, T Dorn, Q Tian, A Goedel, L Dreizehnter, ... European Heart Journal 38 (4), 292-301, 2017 | 103 | 2017 |
MRTF-A controls vessel growth and maturation by increasing the expression of CCN1 and CCN2 R Hinkel, T Trenkwalder, B Petersen, W Husada, F Gesenhues, S Lee, ... Nature communications 5 (1), 3970, 2014 | 99 | 2014 |