Hypoxia-induced exosomes contribute to a more aggressive and chemoresistant ovarian cancer phenotype: a novel mechanism linking STAT3/Rab proteins KDP Dorayappan, R Wanner, JJ Wallbillich, U Saini, R Zingarelli, ... Oncogene 37 (28), 3806-3821, 2018 | 243 | 2018 |
Microfluidic affinity separation chip for selective capture and release of label-free ovarian cancer exosomes CL Hisey, KDP Dorayappan, DE Cohn, K Selvendiran, DJ Hansford Lab on a Chip 18 (20), 3144-3153, 2018 | 144 | 2018 |
Ursolic acid attenuates oxidative stress-mediated hepatocellular carcinoma induction by diethylnitrosamine in male Wistar rats R Gayathri, DK Priya, GR Gunassekaran, D Sakthisekaran Asian Pac J Cancer Prev 10 (5), 933-938, 2009 | 107 | 2009 |
The biological significance and clinical applications of exosomes in ovarian cancer KDP Dorayappan, JJ Wallbillich, DE Cohn, K Selvendiran Gynecologic oncology 142 (1), 199-205, 2016 | 86 | 2016 |
A microfluidic chip enables isolation of exosomes and establishment of their protein profiles and associated signaling pathways in ovarian cancer KDP Dorayappan, ML Gardner, CL Hisey, RA Zingarelli, BQ Smith, ... Cancer research 79 (13), 3503-3513, 2019 | 84 | 2019 |
High glucose-mediated STAT3 activation in endometrial cancer is inhibited by metformin: therapeutic implications for endometrial cancer JJ Wallbillich, S Josyula, U Saini, RA Zingarelli, KDP Dorayappan, ... PLoS One 12 (1), e0170318, 2017 | 48 | 2017 |
Role of sulforaphane in the anti-initiating mechanism of lung carcinogenesis in vivo by modulating the metabolic activation and detoxification of benzo (a) pyrene DKD Priya, R Gayathri, D Sakthisekaran Biomedicine & Pharmacotherapy 65 (1), 9-16, 2011 | 41 | 2011 |
Targeting STAT3 by HO3867 induces apoptosis in ovarian clear cell carcinoma K Bixel, U Saini, H Kumar Bid, J Fowler, M Riley, R Wanner, ... International journal of cancer 141 (9), 1856-1866, 2017 | 28 | 2017 |
Apoptotic role of natural isothiocyanate from broccoli (Brassica oleracea italica) in experimental chemical lung carcinogenesis D Kalpana Deepa Priya, R Gayathri, GR Gunassekaran, S Murugan, ... Pharmaceutical Biology 51 (5), 621-628, 2013 | 27 | 2013 |
Protective role of sulforaphane against oxidative stress mediated mitochondrial dysfunction induced by benzo (a) pyrene in female Swiss albino mice DKD Priya, R Gayathri, GR Gunassekaran, D Sakthisekaran Pulmonary pharmacology & therapeutics 24 (1), 110-117, 2011 | 26 | 2011 |
Taurine regulates mitochondrial function during 7, 12-dimethyl benz [a] anthracene induced experimental mammary carcinogenesis MK Vanitha, KD Priya, K Baskaran, K Periyasamy, D Saravanan, ... Journal of Pharmacopuncture 18 (3), 68, 2015 | 24 | 2015 |
In vitro and in vivo studies on antitumor effects of gossypol on human stomach adenocarcinoma (AGS) cell line and MNNG induced experimental gastric cancer GR Gunassekaran, DKD Priya, R Gayathri, D Sakthisekaran Biochemical and Biophysical Research Communications 411 (4), 661-666, 2011 | 21 | 2011 |
Chemopreventive role of sulforaphane by upholding the GSH redox cycle in pre-and post-initiation phases of experimental lung carcinogenesis DK Priya, R Gayathri, GR Gunassekaran, S Murugan, D Sakthisekaran Asian Pac J Cancer Prev 12 (1), 103-10, 2011 | 21 | 2011 |
Inhibitory effect of sulforaphane against benzo (a) pyrene induced lung cancer by modulation of biochemical signatures in female Swiss albino mice. DKD Priya, R Gayathri, GR Gunassekaran, S Murugan, D Sakthisekaran Asian Journal of Biochemistry 6 (5), 395-405, 2011 | 13 | 2011 |
Protective role of gossypol against N-methyl-N’-nitro-N-nitrosoguanidine (MNNG) induced gastric carcinogenesis in experimental rats GR Gunassekaran, R Gayathri, DKD Priya, S Murugan, D Sakithsekaran International Journal of Medicine and Medical Sciences 2 (4), 121-127, 2010 | 12 | 2010 |
Phytochemical analysis of medicinal mangrove plant species Ceriops decandra P Thirunavukkarasu, S Asha, R Reddy, D Priya, R Hari, N Sudhakar Global Journal of Pharmacology 12 (1), 24-30, 2018 | 10 | 2018 |
Aberrant expression of TMEM205 signaling promotes platinum resistance in ovarian cancer: An implication for the antitumor potential of DAP compound CA Calo, BQ Smith, KDP Dorayappan, U Saini, M Lightfoot, V Wagner, ... Gynecologic oncology 164 (1), 136-145, 2022 | 8 | 2022 |
Hypoxia-facilitated exosomal release from ovarian cancer cells is regulated by STAT3 and is associated with increased metastatic tumor burden KDP Dorayappan, JJ Wallbillich, U Saini, K Bixel, MK Riley, RA Zingarelli, ... Gynecologic oncology 141, 66, 2016 | 3 | 2016 |
Targeting TMEM205 mediated drug resistance in ovarian clear cell carcinoma using oncolytic virus U Saini, BQ Smith, KDP Dorayappan, JY Yoo, GL Maxwell, B Kaur, ... Journal of Ovarian Research 15 (1), 130, 2022 | 2 | 2022 |
Aberrant TMEM205-CD1B signaling promotes platinum resistance in ovarian cancer BQ Smith, U Saini, KDP Dorayappan, MK Riley, RA Zingarelli, R Wanner, ... Gynecologic Oncology 149, 65, 2018 | 2 | 2018 |