Follow
John Kibuthu Thuita
John Kibuthu Thuita
Senior Lecturer, Meru University of Science & Technology
Verified email at must.ac.ke - Homepage
Title
Cited by
Cited by
Year
Diamidines for human African trypanosomiasis
WD Wilson, HP De Koningº, CA Olson, G Pohlig
Current Opinion in Investigational Drugs 11 (8), 876-883, 2010
1482010
Efficacy of the diamidine DB75 and its prodrug DB289, against murine models of human African trypanosomiasis
JK Thuita, SM Karanja, T Wenzler, RE Mdachi, JM Ngotho, JM Kagira, ...
Acta Tropica 108 (1), 6-10, 2008
1062008
Trypanosoma brucei rhodesiense Transmitted by a Single Tsetse Fly Bite in Vervet Monkeys as a Model of Human African Trypanosomiasis
JK Thuita, JM Kagira, D Mwangangi, E Matovu, CMR Turner, D Masiga
PLoS neglected tropical diseases 2 (5), e238, 2008
732008
Hematological changes in vervet monkeys (Chlorocebus aethiops) during eight months' adaptation to captivity
JM Kagira, M Ngotho, JK Thuita, NW Maina, J Hau
American Journal of Primatology: Official Journal of the American Society of …, 2007
72*2007
Haematology of experimental Trypanosoma brucei rhodesiense infection in vervet monkeys
JM Kagira, JK Thuita, M Ngotho, R Mdachi, DM Mwangangi, JM Ndung'u
African Journal of Health Sciences 13 (3), 59-65, 2006
622006
Efficacy of the novel diamidine compound 2, 5-Bis (4-amidinophenyl)-furan-bis-O-Methlylamidoxime (Pafuramidine, DB289) against Trypanosoma brucei rhodesiense infection in …
RE Mdachi, JK Thuita, JM Kagira, JM Ngotho, GA Murilla, JM Ndung'u, ...
Antimicrobial agents and chemotherapy 53 (3), 953-957, 2009
532009
Pharmacology of DB844, an orally active aza analogue of pafuramidine, in a monkey model of second stage human African trypanosomiasis
JK Thuita, MZ Wang, JM Kagira, CL Denton, MF Paine, RE Mdachi, ...
PLoS neglected tropical diseases 6 (7), e1734, 2012
482012
Proinflammatory Cytokine Expression in the Early Phase of Trypanosoma brucei rhodesiense Infection in Vervet Monkeys (Cercopithecus aethiops)
N Maina, JM Ngotho, T Were, JK Thuita, DM Mwangangi, JM Kagira, ...
Infection and immunity 72 (5), 3063-3065, 2004
342004
Chemotherapy of second stage human African trypanosomiasis: comparison between the parenteral diamidine DB829 and its oral prodrug DB868 in vervet monkeys
JK Thuita, KK Wolf, GA Murilla, AS Bridges, DW Boykin, JN Mutuku, Q Liu, ...
PLoS neglected tropical diseases 9 (2), e0003409, 2015
30*2015
Influence of trypanocidal therapy on the haematology of vervet monkeys experimentally infected with Trypanosoma brucei rhodesiense
M Ngotho, JM Kagira, C Kariuki, N Maina, JK Thuita, DM Mwangangi, ...
Acta tropica 119 (1), 14-18, 2011
262011
Safety, pharmacokinetic, and efficacy studies of oral DB868 in a first stage vervet monkey model of human African trypanosomiasis
JK Thuita, KK Wolf, GA Murilla, Q Liu, JN Mutuku, Y Chen, AS Bridges, ...
PLoS neglected tropical diseases 7 (6), e2230, 2013
252013
Development of a rodent model for late stage rhodesian sleeping sickness
JM Kagira, M Ngotho, J Thuita
The journal of protozoology research 17 (2), 48-56, 2007
212007
Kenya Trypanosomiasis Research Institute cryobank for human and animal trypanosome isolates to support research: opportunities and challenges
GA Murilla, K Ndung'u, JK Thuita, PK Gitonga, DT Kahiga, JE Auma, ...
PLoS Neglected Tropical Diseases 8 (5), e2747, 2014
172014
Differential virulence and tsetse fly transmissibility of Trypanosoma congolense and Trypanosoma brucei strains
PK Gitonga, GA Murilla, K Ndung’u, PC Thande, FN Wamwiri, JE Auma, ...
Onderstepoort Journal of Veterinary Research 84 (1), 1-10, 2017
162017
Differential virulence of Trypanosoma brucei rhodesiense isolates does not influence the outcome of treatment with anti-trypanosomal drugs in the mouse model
K Ndung’u, GA Murilla, JK Thuita, GN Ngae, JE Auma, PK Gitonga, ...
PLoS One 15 (11), e0229060, 2020
15*2020
Route of inoculation influences Trypanosoma congolense and Trypanosoma brucei brucei virulence in Swiss white mice
K Ndungu, D Thungu, F Wamwiri, P Mireji, G Ngae, P Gitonga, J Mulinge, ...
PLoS One 14 (6), e0218441, 2019
132019
The prickly pear cactus (Opuntia fiscus-indica) cladode extracts modulate blood sugar in swiss white albino mice
PM Mokua, O Mayunzu, M Obonyo, J Thuita, J Mutuku, J Rutto, G Murilla
International Journal of Diabetes Research, 2016
112016
Coenzyme Q10 and endogenous antioxidants neuro-protect mice brain against deleterious effects of melarsoprol and Trypanasoma brucei rhodesiense
JN Nyariki, JK Thuita, AM Wambugu, NO Nyamweya, K Rashid, ...
J. Nat. Sci. Res 8 (4), 61-73, 2018
102018
Influence of cyclophosphamide on the haematological profile of laboratory bred African soft-furred rats (Mastomys natalensis)
JM Kagira, N Maina, JK Thuita, M Ngotho, J Hau
102005
Comparative pathogenicity of Trypanosoma brucei rhodesiense strains in Swiss white mice and Mastomys natalensis rats
MW Muchiri, K Ndung’u, JK Kibugu, JK Thuita, PK Gitonga, GN Ngae, ...
Acta tropica 150, 23-28, 2015
92015
The system can't perform the operation now. Try again later.
Articles 1–20