Aaron A. Thompson
Aaron A. Thompson
The Janssen Pharmaceutical Companies of Johnson & Johnson
Verified email at
Cited by
Cited by
Structure of the human κ-opioid receptor in complex with JDTic
H Wu, D Wacker, M Mileni, V Katritch, GW Han, E Vardy, W Liu, ...
Nature 485 (7398), 327-332, 2012
Structural basis for allosteric regulation of GPCRs by sodium ions
W Liu, E Chun, AA Thompson, P Chubukov, F Xu, V Katritch, GW Han, ...
Science 337 (6091), 232-236, 2012
Structure of the nociceptin/orphanin FQ receptor in complex with a peptide mimetic
AA Thompson, W Liu, E Chun, V Katritch, H Wu, E Vardy, XP Huang, ...
Nature 485 (7398), 395-399, 2012
Molecular control of δ-opioid receptor signalling
G Fenalti, PM Giguere, V Katritch, XP Huang, AA Thompson, V Cherezov, ...
Nature 506 (7487), 191-196, 2014
Fusion partner toolchest for the stabilization and crystallization of G protein-coupled receptors
E Chun, AA Thompson, W Liu, CB Roth, MT Griffith, V Katritch, J Kunken, ...
Structure 20 (6), 967-976, 2012
Structural basis for proteolysis‐dependent activation of the poliovirus RNA‐dependent RNA polymerase
AA Thompson, OB Peersen
The EMBO journal 23 (17), 3462-3471, 2004
GPCR stabilization using the bicelle-like architecture of mixed sterol-detergent micelles
AA Thompson, JJ Liu, E Chun, D Wacker, H Wu, V Cherezov, RC Stevens
Methods 55 (4), 310-317, 2011
Analysis of flavivirus NS5 methyltransferase cap binding
BJ Geiss, AA Thompson, AJ Andrews, RL Sons, HH Gari, SM Keenan, ...
Journal of molecular biology 385 (5), 1643-1654, 2009
A single-domain llama antibody potently inhibits the enzymatic activity of botulinum neurotoxin by binding to the non-catalytic α-exosite binding region
J Dong, AA Thompson, Y Fan, J Lou, F Conrad, M Ho, M Pires-Alves, ...
Journal of molecular biology 397 (4), 1106-1118, 2010
The importance of ligand-receptor conformational pairs in stabilization: spotlight on the N/OFQ G protein-coupled receptor
RL Miller, AA Thompson, C Trapella, R Guerrini, D Malfacini, N Patel, ...
Structure 23 (12), 2291-2299, 2015
Stabilization of poliovirus polymerase by NTP binding and fingers–thumb interactions
AA Thompson, RA Albertini, OB Peersen
Journal of molecular biology 366 (5), 1459-1474, 2007
Biochemical characterization of recombinant hepatitis C virus nonstructural protein 4B: evidence for ATP/GTP hydrolysis and adenylate kinase activity
AA Thompson, A Zou, J Yan, R Duggal, W Hao, D Molina, CN Cronin, ...
Biochemistry 48 (5), 906-916, 2009
Structural Characterization of Three Novel Hydroxamate-Based Zinc Chelating Inhibitors of the Clostridium botulinum Serotype A Neurotoxin Light Chain …
AA Thompson, GS Jiao, S Kim, A Thai, L Cregar-Hernandez, ...
Biochemistry 50 (19), 4019-4028, 2011
Nucleotide channel of RNA-dependent RNA polymerase used for intermolecular uridylylation of protein primer
AB Tellez, S Crowder, JF Spagnolo, AA Thompson, OB Peersen, ...
Journal of molecular biology 357 (2), 665-675, 2006
Synthesis and properties of dodecyl trehaloside detergents for membrane protein studies
H Tao, Y Fu, A Thompson, SC Lee, N Mahoney, RC Stevens, Q Zhang
Langmuir 28 (30), 11173-11181, 2012
Composition and process for the generation of a clear or translucent emissive coating
N Smith, CJ Gruszka, A Thompson, M Deemer
US Patent 11,142,654, 2021
Novel fusion partners for the purpose of crystallizing g-protein coupled receptors
MA Hanson, CB Roth, RC Stevens, JM Kunken, MT Griffith, AA Thompson, ...
US Patent App. 13/470,104, 2012
Method for rapid optimization of recombinant GPCR protein expression and stability using virus-like particles
TT Ho, JT Nguyen, J Liu, P Stanczak, AA Thompson, YG Yan, J Chen, ...
Protein Expression and Purification 133, 41-49, 2017
Identification of small-molecule protein–protein interaction inhibitors for NKG2D
AA Thompson, MB Harbut, PP Kung, NK Karpowich, JD Branson, ...
Proceedings of the National Academy of Sciences 120 (18), e2216342120, 2023
Full wwPDB X-ray Structure Validation Report i
H Wang, E Gouaux
Word wide protein data bank, 2009
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