| Enhancer hijacking activates GFI1 family oncogenes in medulloblastoma PA Northcott, C Lee, T Zichner, AM Stütz, S Erkek, D Kawauchi, DJH Shih, ... Nature 511 (7510), 428-434, 2014 | 720 | 2014 |
| Cyclin D expression is controlled post-transcriptionally via a phosphatidylinositol 3-kinase/Akt-dependent pathway RC Muise-Helmericks, HL Grimes, A Bellacosa, SE Malstrom, PN Tsichlis, ... Journal of Biological Chemistry 273 (45), 29864-29872, 1998 | 686 | 1998 |
| Transduction of interleukin-2 antiapoptotic and proliferative signals via Akt protein kinase NN Ahmed, HL Grimes, A Bellacosa, TO Chan, PN Tsichlis Proceedings of the National Academy of Sciences 94 (8), 3627-3632, 1997 | 666 | 1997 |
| Suppression of IL7Rα transcription by IL-7 and other prosurvival cytokines: a novel mechanism for maximizing IL-7-dependent T cell survival JH Park, Q Yu, B Erman, JS Appelbaum, D Montoya-Durango, HL Grimes, ... Immunity 21 (2), 289-302, 2004 | 596 | 2004 |
| Single-cell analysis of mixed-lineage states leading to a binary cell fate choice A Olsson, M Venkatasubramanian, VK Chaudhri, BJ Aronow, ... Nature 537 (7622), 698-702, 2016 | 522 | 2016 |
| Mutations in proto-oncogene GFI1 cause human neutropenia and target ELA2 RE Person, FQ Li, Z Duan, KF Benson, J Wechsler, HA Papadaki, ... Nature genetics 34 (3), 308-312, 2003 | 450 | 2003 |
| Granulocyte-monocyte progenitors and monocyte-dendritic cell progenitors independently produce functionally distinct monocytes A Yáńez, SG Coetzee, A Olsson, DE Muench, BP Berman, DJ Hazelett, ... Immunity 47 (5), 890-902. e4, 2017 | 422 | 2017 |
| Gfi-1 encodes a nuclear zinc finger protein that binds DNA and functions as a transcriptional repressor PA Zweidler-McKay, HL Grimes, MM Flubacher, PN Tsichlis Molecular and cellular biology 16 (8), 4024-4034, 1996 | 390 | 1996 |
| Akt phosphorylates the Y-box binding protein 1 at Ser102 located in the cold shock domain and affects the anchorage-independent growth of breast cancer cells BW Sutherland, J Kucab, J Wu, C Lee, MCU Cheang, E Yorida, D Turbin, ... Oncogene 24 (26), 4281-4292, 2005 | 372 | 2005 |
| The Gfi-1 proto-oncoprotein contains a novel transcriptional repressor domain, SNAG, and inhibits G1 arrest induced by interleukin-2 withdrawal HL Grimes, TO Chan, PA Zweidler-McKay, B Tong, PN Tsichlis Molecular and cellular biology 16 (11), 6263-6272, 1996 | 358 | 1996 |
| The zinc finger transcription factor Gfi1, implicated in lymphomagenesis, is required for inner ear hair cell differentiation and survival D Wallis, M Hamblen, Y Zhou, KJT Venken, A Schumacher, HL Grimes, ... Oxford University Press for The Company of Biologists Limited 130 (1), 221-232, 2003 | 304 | 2003 |
| Bim/Bcl-2 balance is critical for maintaining naive and memory T cell homeostasis S Wojciechowski, P Tripathi, T Bourdeau, L Acero, HL Grimes, JD Katz, ... The Journal of experimental medicine 204 (7), 1665-1675, 2007 | 286 | 2007 |
| Regulation of mir-196b by MLL and its overexpression by MLL fusions contributes to immortalization R Popovic, LE Riesbeck, CS Velu, A Chaubey, J Zhang, NJ Achille, ... Blood, The Journal of the American Society of Hematology 113 (14), 3314-3322, 2009 | 272 | 2009 |
| Progression of interleukin-2 (IL-2)-dependent rat T cell lymphoma lines to IL-2-independent growth following activation of a gene (Gfi-1) encoding a novel zinc finger protein CB Gilks, SE Bear, HL Grimes, PN Tsichlis Molecular and Cellular Biology 13 (3), 1759-1768, 1993 | 271 | 1993 |
| Transcription factor RUNX1 promotes survival of acute myeloid leukemia cells S Goyama, J Schibler, L Cunningham, Y Zhang, Y Rao, N Nishimoto, ... The Journal of clinical investigation 123 (9), 3876-3888, 2013 | 234 | 2013 |
| Gfi1 regulates miR-21 and miR-196b to control myelopoiesis CS Velu, AM Baktula, HL Grimes Blood, The Journal of the American Society of Hematology 113 (19), 4720-4728, 2009 | 220 | 2009 |
| The Human Cell Atlas bone marrow single-cell interactive web portal SB Hay, K Ferchen, K Chetal, HL Grimes, N Salomonis Experimental hematology 68, 51-61, 2018 | 216 | 2018 |
| P63 expression in lung carcinoma: a tissue microarray study of 408 cases NHC Au, AM Gown, M Cheang, D Huntsman, E Yorida, WM Elliott, J Flint, ... Applied Immunohistochemistry & Molecular Morphology 12 (3), 240-247, 2004 | 205 | 2004 |
| Combinatorial single-cell analyses of granulocyte-monocyte progenitor heterogeneity reveals an early uni-potent neutrophil progenitor I Kwok, E Becht, Y Xia, M Ng, YC Teh, L Tan, M Evrard, JLY Li, HTN Tran, ... Immunity 53 (2), 303-318. e5, 2020 | 203 | 2020 |
| Gfi1 Coordinates Epigenetic Repression of p21Cip/WAF1 by Recruitment of Histone Lysine Methyltransferase G9a and Histone Deacetylase 1 Z Duan, A Zarebski, D Montoya-Durango, HL Grimes, M Horwitz Molecular and cellular biology 25 (23), 10338-10351, 2005 | 202 | 2005 |
