Megan L. Hochstrasser
Megan L. Hochstrasser
Arcadia Science
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CasA mediates Cas3-catalyzed target degradation during CRISPR RNA-guided interference
ML Hochstrasser, DW Taylor, P Bhat, CK Guegler, SH Sternberg, ...
Proceedings of the National Academy of Sciences 111 (18), 6618-6623, 2014
Cutting it close: CRISPR-associated endoribonuclease structure and function
ML Hochstrasser, JA Doudna
Trends in Biochemical Sciences 40 (1), 58-66, 2015
DNA targeting by a minimal CRISPR RNA-guided Cascade
ML Hochstrasser, DW Taylor, JE Kornfeld, E Nogales, JA Doudna
Molecular Cell 63 (5), 840-851, 2016
Clinical applications of CRISPR‐based genome editing and diagnostics
DV Foss, ML Hochstrasser, RC Wilson
Transfusion 59 (4), 1389-1399, 2019
Spatial quality control bypasses cell-based limitations on proteostasis to promote prion curing
CL Klaips, ML Hochstrasser, CR Langlois, TR Serio
Elife 3, e04288, 2014
Blueprint for a pop-up SARS-CoV-2 testing lab
Nature Biotechnology 38 (7), 791-797, 2020
Enhanced genome editing with Cas9 ribonucleoprotein in diverse cells and organisms
B Farboud, E Jarvis, TL Roth, J Shin, JE Corn, A Marson, BJ Meyer, ...
JoVE (Journal of Visualized Experiments), e57350, 2018
Launching a saliva-based SARS-CoV-2 surveillance testing program on a university campus
AJ Ehrenberg, EA Moehle, CE Brook, AH Doudna Cate, LB Witkowsky, ...
PLoS One 16 (5), e0251296, 2021
A single amino acid substitution converts a transmembrane protein activator of the platelet-derived growth factor β receptor into an inhibitor
LM Petti, K Talbert-Slagle, ML Hochstrasser, D DiMaio
Journal of Biological Chemistry 288 (38), 27273-27286, 2013
CRISPR meets caspase
ML Hochstrasser, JK Nuņez
Nature Microbiology 6 (12), 1481-1482, 2021
The experiment begins: Arcadia publishing 1.0
P Avasthi, ML Hochstrasser
Arcadia Science, 2022
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