CasA mediates Cas3-catalyzed target degradation during CRISPR RNA-guided interference ML Hochstrasser, DW Taylor, P Bhat, CK Guegler, SH Sternberg, ... Proceedings of the National Academy of Sciences 111 (18), 6618-6623, 2014 | 239 | 2014 |
Cutting it close: CRISPR-associated endoribonuclease structure and function ML Hochstrasser, JA Doudna Trends in Biochemical Sciences 40 (1), 58-66, 2015 | 136 | 2015 |
DNA targeting by a minimal CRISPR RNA-guided Cascade ML Hochstrasser, DW Taylor, JE Kornfeld, E Nogales, JA Doudna Molecular Cell 63 (5), 840-851, 2016 | 85 | 2016 |
Clinical applications of CRISPR‐based genome editing and diagnostics DV Foss, ML Hochstrasser, RC Wilson Transfusion 59 (4), 1389-1399, 2019 | 50 | 2019 |
Spatial quality control bypasses cell-based limitations on proteostasis to promote prion curing CL Klaips, ML Hochstrasser, CR Langlois, TR Serio Elife 3, e04288, 2014 | 49 | 2014 |
Blueprint for a pop-up SARS-CoV-2 testing lab Nature Biotechnology 38 (7), 791-797, 2020 | 47 | 2020 |
Enhanced genome editing with Cas9 ribonucleoprotein in diverse cells and organisms B Farboud, E Jarvis, TL Roth, J Shin, JE Corn, A Marson, BJ Meyer, ... JoVE (Journal of Visualized Experiments), e57350, 2018 | 43 | 2018 |
Launching a saliva-based SARS-CoV-2 surveillance testing program on a university campus AJ Ehrenberg, EA Moehle, CE Brook, AH Doudna Cate, LB Witkowsky, ... PLoS One 16 (5), e0251296, 2021 | 19 | 2021 |
A single amino acid substitution converts a transmembrane protein activator of the platelet-derived growth factor β receptor into an inhibitor LM Petti, K Talbert-Slagle, ML Hochstrasser, D DiMaio Journal of Biological Chemistry 288 (38), 27273-27286, 2013 | 9 | 2013 |
CRISPR meets caspase ML Hochstrasser, JK Nuņez Nature Microbiology 6 (12), 1481-1482, 2021 | 4 | 2021 |
The experiment begins: Arcadia publishing 1.0 P Avasthi, ML Hochstrasser Arcadia Science, 2022 | | 2022 |