Monoclonal TCR-redirected tumor cell killing N Liddy, G Bossi, KJ Adams, A Lissina, TM Mahon, NJ Hassan, J Gavarret, ... Nature medicine 18 (6), 980-987, 2012 | 1070 | 2012 |
Dominantly inherited hyperinsulinism caused by a mutation in the sulfonylurea receptor type 1 H Huopio, F Reimann, R Ashfield, J Komulainen, HL Lenko, J Rahier, ... The Journal of clinical investigation 106 (7), 897-906, 2000 | 308 | 2000 |
Identification of the high-affinity tolbutamide site on the SUR1 subunit of the K (ATP) channel. R Ashfield, FM Gribble, SJ Ashcroft, FM Ashcroft Diabetes 48 (6), 1341-1347, 1999 | 258 | 1999 |
Properties of cloned ATP‐sensitive K+ currents expressed in Xenopus oocytes. FM Gribble, R Ashfield, C Ammälä, FM Ashcroft The Journal of physiology 498 (1), 87-98, 1997 | 245 | 1997 |
Association studies of variants in promoter and coding regions of beta‐cell ATP‐sensitive K‐channel genes SUR1 and Kir6.2 with Type 2 diabetes mellitus … AL Gloyn, Y Hashim, SJH Ashcroft, R Ashfield, S Wiltshire, RC Turner Diabetic Medicine 18 (3), 206-212, 2001 | 234 | 2001 |
Structure of malaria invasion protein RH5 with erythrocyte basigin and blocking antibodies KE Wright, KA Hjerrild, J Bartlett, AD Douglas, J Jin, RE Brown, ... Nature 515 (7527), 427-430, 2014 | 228 | 2014 |
Promiscuous coupling between the sulphonylurea receptor and inwardly rectifying potassium channels C Ämmälä, A Moorhouse, F Gribble, R Ashfleld, P Proks, PA Smith, ... Nature 379 (6565), 545-548, 1996 | 200 | 1996 |
A point mutation inactivating the sulfonylurea receptor causes the severe form of persistent hyperinsulinemic hypoglycemia of infancy in Finland. T Otonkoski, C Ammälä, H Huopio, GJ Cote, J Chapman, K Cosgrove, ... Diabetes 48 (2), 408-415, 1999 | 195 | 1999 |
Human vaccination against RH5 induces neutralizing antimalarial antibodies that inhibit RH5 invasion complex interactions RO Payne, SE Silk, SC Elias, K Miura, A Diouf, F Galaway, H De Graaf, ... JCI insight 2 (21), 2017 | 153 | 2017 |
MAZ‐dependent termination between closely spaced human complement genes. R Ashfield, AJ Patel, SA Bossone, H Brown, RD Campbell, KB Marcu, ... The EMBO journal 13 (23), 5656-5667, 1994 | 152 | 1994 |
Bi-specific TCR-anti CD3 redirected T-cell targeting of NY-ESO-1-and LAGE-1-positive tumors E McCormack, KJ Adams, NJ Hassan, A Kotian, NM Lissin, M Sami, ... Cancer Immunology, Immunotherapy 62, 773-785, 2013 | 144 | 2013 |
Reduced blood-stage malaria growth and immune correlates in humans following RH5 vaccination AM Minassian, SE Silk, JR Barrett, CM Nielsen, K Miura, A Diouf, C Loos, ... Med 2 (6), 701-719. e19, 2021 | 133 | 2021 |
Oncolytic adenovirus expressing bispecific antibody targets T‐cell cytotoxicity in cancer biopsies JD Freedman, J Hagel, EM Scott, I Psallidas, A Gupta, L Spiers, P Miller, ... EMBO molecular medicine 9 (8), 1067-1087, 2017 | 133 | 2017 |
Better epitope discovery, precision immune engineering, and accelerated vaccine design using immunoinformatics tools AS De Groot, L Moise, F Terry, AH Gutierrez, P Hindocha, G Richard, ... Frontiers in immunology 11, 442, 2020 | 129 | 2020 |
Transcriptional termination between the closely linked human complement genes C2 and factor B: common termination factor for C2 and c‐myc? R Ashfield, P Enriquez‐Harris, NJ Proudfoot The EMBO journal 10 (13), 4197-4207, 1991 | 87 | 1991 |
Accelerating the clinical development of protein-based vaccines for malaria by efficient purification using a four amino acid C-terminal ‘C-tag’ J Jin, KA Hjerrild, SE Silk, RE Brown, GM Labbé, JM Marshall, KE Wright, ... International journal for parasitology 47 (7), 435-446, 2017 | 75 | 2017 |
Production of full-length soluble Plasmodium falciparum RH5 protein vaccine using a Drosophila melanogaster Schneider 2 stable cell line system KA Hjerrild, J Jin, KE Wright, RE Brown, JM Marshall, GM Labbé, SE Silk, ... Scientific reports 6 (1), 30357, 2016 | 72 | 2016 |
Production, quality control, stability, and potency of cGMP-produced Plasmodium falciparum RH5.1 protein vaccine expressed in Drosophila S2 cells J Jin, RD Tarrant, EJ Bolam, P Angell-Manning, M Soegaard, ... npj Vaccines 3 (1), 32, 2018 | 67 | 2018 |
The HLA A*0201–restricted hTERT540–548 peptide is not detected on tumor cells by a CTL clone or a high-affinity T-cell receptor MA Purbhoo, Y Li, DH Sutton, JE Brewer, E Gostick, G Bossi, B Laugel, ... Molecular cancer therapeutics 6 (7), 2081-2091, 2007 | 60 | 2007 |
Cloning and functional expression of the cDNA encoding an inwardly-rectifying potassium channel expressed in pancreatic β-cells and in the brain CT Bond, C Ämmälä, R Ashfield, TA Blair, F Gribble, RN Khan, K Lee, ... FEBS letters 367 (1), 61-66, 1995 | 58 | 1995 |