The TREM2-APOE pathway drives the transcriptional phenotype of dysfunctional microglia in neurodegenerative diseases S Krasemann, C Madore, R Cialic, C Baufeld, N Calcagno, R El Fatimy, ... Immunity 47 (3), 566-581. e9, 2017 | 1955 | 2017 |
Pan-viral specificity of IFN-induced genes reveals new roles for cGAS in innate immunity JW Schoggins, DA MacDuff, N Imanaka, MD Gainey, B Shrestha, ... Nature 505 (7485), 691-695, 2014 | 916 | 2014 |
Unexpected role of interferon-γ in regulating neuronal connectivity and social behaviour AJ Filiano, Y Xu, NJ Tustison, RL Marsh, W Baker, I Smirnov, CC Overall, ... Nature 535 (7612), 425-429, 2016 | 633 | 2016 |
Function of C/EBPδ in a regulatory circuit that discriminates between transient and persistent TLR4-induced signals V Litvak, SA Ramsey, AG Rust, DE Zak, KA Kennedy, AE Lampano, ... Nature immunology 10 (4), 437-443, 2009 | 331 | 2009 |
Uncovering a macrophage transcriptional program by integrating evidence from motif scanning and expression dynamics SA Ramsey, SL Klemm, DE Zak, KA Kennedy, V Thorsson, B Li, ... PLoS computational biology 4 (3), e1000021, 2008 | 223 | 2008 |
Maintenance of the diacylglycerol level in the Golgi apparatus by the Nir2 protein is critical for Golgi secretory function V Litvak, N Dahan, S Ramachandran, H Sabanay, S Lev Nature cell biology 7 (3), 225-234, 2005 | 201 | 2005 |
Methyl-CpG binding protein 2 regulates microglia and macrophage gene expression in response to inflammatory stimuli JC Cronk, NC Derecki, E Ji, Y Xu, AE Lampano, I Smirnov, W Baker, ... Immunity 42 (4), 679-691, 2015 | 192 | 2015 |
A FOXO3–IRF7 gene regulatory circuit limits inflammatory sequelae of antiviral responses V Litvak, AV Ratushny, AE Lampano, F Schmitz, AC Huang, A Raman, ... Nature 490 (7420), 421-425, 2012 | 167 | 2012 |
The methyltransferase Setdb2 mediates virus-induced susceptibility to bacterial superinfection C Schliehe, EK Flynn, B Vilagos, U Richson, S Swaminathan, B Bosnjak, ... Nature immunology 16 (1), 67-74, 2015 | 133 | 2015 |
A disaccharide derived from chondroitin sulphate proteoglycan promotes central nervous system repair in rats and mice† A Rolls, H Avidan, L Cahalon, H Schori, S Bakalash, V Litvak, S Lev, ... European Journal of Neuroscience 20 (8), 1973-1983, 2004 | 108 | 2004 |
Mitotic phosphorylation of the peripheral Golgi protein Nir2 by Cdk1 provides a docking mechanism for Plk1 and affects cytokinesis completion V Litvak, R Argov, N Dahan, S Ramachandran, R Amarilio, A Shainskaya, ... Molecular cell 14 (3), 319-330, 2004 | 108 | 2004 |
Targeting of PYK2 to focal adhesions as a cellular mechanism for convergence between integrins and G protein-coupled receptor signaling cascades V Litvak, D Tian, YD Shaul, S Lev Journal of Biological Chemistry 275 (42), 32736-32746, 2000 | 108 | 2000 |
Genome-wide histone acetylation data improve prediction of mammalian transcription factor binding sites SA Ramsey, TA Knijnenburg, KA Kennedy, DE Zak, M Gilchrist, ES Gold, ... Bioinformatics 26 (17), 2071-2075, 2010 | 90 | 2010 |
Cerebral ischemia and seizures induce tyrosine phosphorylation of PYK2 in neurons and microglial cells D Tian, V Litvak, S Lev Journal of Neuroscience 20 (17), 6478-6487, 2000 | 75 | 2000 |
Targeting of Nir2 to lipid droplets is regulated by a specific threonine residue within its PI-transfer domain V Litvak, YD Shaul, M Shulewitz, R Amarilio, S Carmon, S Lev Current Biology 12 (17), 1513-1518, 2002 | 62 | 2002 |
Nir2, a Human Homolog of Drosophila melanogaster Retinal Degeneration B Protein, Is Essential for Cytokinesis V Litvak, D Tian, S Carmon, S Lev Molecular and cellular biology 22 (14), 5064-5075, 2002 | 51 | 2002 |
Induction of a Unique Isoform of the NCOA7 Oxidation Resistance Gene by Interferon β-1b L Yu, E Croze, KD Yamaguchi, T Tran, AT Reder, V Litvak, MR Volkert Journal of interferon & cytokine research 35 (3), 186-199, 2015 | 38 | 2015 |
Unexpected cellular players in Rett syndrome pathology JC Cronk, NC Derecki, V Litvak, J Kipnis Neurobiology of disease 92, 64-71, 2016 | 36 | 2016 |
Nir2, a novel regulator of cell morphogenesis D Tian, V Litvak, M Toledo-Rodriguez, S Carmon, S Lev Molecular and cellular biology 22 (8), 2650-2662, 2002 | 27 | 2002 |
Role of the transcription factor C/EBPδ in a regulatory circuit that discriminates between transient and persistent Toll-like receptor 4-induced signals V Litvak, SA Ramsey, AG Rust, DE Zak, KA Kennedy, AE Lampano, ... Nature immunology 10 (4), 437, 2009 | 7 | 2009 |