AMPK phosphorylates and inhibits SREBP activity to attenuate hepatic steatosis and atherosclerosis in diet-induced insulin-resistant mice YU Li, S Xu, MM Mihaylova, B Zheng, X Hou, B Jiang, O Park, Z Luo, ... Cell metabolism 13 (4), 376-388, 2011 | 1798 | 2011 |
SIRT1 regulates hepatocyte lipid metabolism through activating AMP-activated protein kinase X Hou, S Xu, KA Maitland-Toolan, K Sato, B Jiang, Y Ido, F Lan, K Walsh, ... Journal of Biological Chemistry 283 (29), 20015-20026, 2008 | 922 | 2008 |
Polyphenols stimulate AMP-activated protein kinase, lower lipids, and inhibit accelerated atherosclerosis in diabetic LDL receptor–deficient mice M Zang, S Xu, KA Maitland-Toolan, A Zuccollo, X Hou, B Jiang, ... Diabetes 55 (8), 2180-2191, 2006 | 791 | 2006 |
SIRT1 deacetylates and inhibits SREBP-1C activity in regulation of hepatic lipid metabolism B Ponugoti, DH Kim, Z Xiao, Z Smith, J Miao, M Zang, SY Wu, CM Chiang, ... Journal of Biological Chemistry 285 (44), 33959-33970, 2010 | 580 | 2010 |
AMP-activated protein kinase is required for the lipid-lowering effect of metformin in insulin-resistant human HepG2 cells M Zang, A Zuccollo, X Hou, D Nagata, K Walsh, H Herscovitz, P Brecher, ... Journal of Biological Chemistry 279 (46), 47898-47905, 2004 | 578 | 2004 |
AMPK as a metabolic tumor suppressor: control of metabolism and cell growth Z Luo, M Zang, W Guo Future oncology 6 (3), 457-470, 2010 | 465 | 2010 |
Hepatic overexpression of SIRT1 in mice attenuates endoplasmic reticulum stress and insulin resistance in the liver Y Li, S Xu, A Giles, K Nakamura, JW Lee, X Hou, G Donmez, J Li, Z Luo, ... The FASEB Journal 25 (5), 1664, 2011 | 344 | 2011 |
Hepatic SIRT1 attenuates hepatic steatosis and controls energy balance in mice by inducing fibroblast growth factor 21 Y Li, K Wong, A Giles, J Jiang, JW Lee, AC Adams, A Kharitonenkov, ... Gastroenterology 146 (2), 539-549. e7, 2014 | 307 | 2014 |
AMPK activation by metformin suppresses abnormal extracellular matrix remodeling in adipose tissue and ameliorates insulin resistance in obesity T Luo, A Nocon, J Fry, A Sherban, X Rui, B Jiang, XJ Xu, J Han, Y Yan, ... Diabetes 65 (8), 2295-2310, 2016 | 188 | 2016 |
Fibroblast growth factor 21 improves hepatic insulin sensitivity by inhibiting mammalian target of rapamycin complex 1 in mice QI Gong, Z Hu, F Zhang, A Cui, X Chen, H Jiang, J Gao, X Chen, Y Han, ... Hepatology 64 (2), 425-438, 2016 | 165 | 2016 |
Aging aggravates alcoholic liver injury and fibrosis in mice by downregulating sirtuin 1 expression T Ramirez, YM Li, S Yin, MJ Xu, D Feng, Z Zhou, M Zang, ... Journal of hepatology 66 (3), 601-609, 2017 | 156 | 2017 |
Erbin suppresses the MAP kinase pathway YZ Huang, M Zang, WC Xiong, Z Luo, L Mei Journal of Biological Chemistry 278 (2), 1108-1114, 2003 | 154 | 2003 |
Interaction between active Pak1 and Raf-1 is necessary for phosphorylation and activation of Raf-1 M Zang, C Hayne, Z Luo Journal of Biological Chemistry 277 (6), 4395-4405, 2002 | 147 | 2002 |
AMPK exerts dual regulatory effects on the PI3K pathway R Tao, J Gong, X Luo, M Zang, W Guo, R Wen, Z Luo Journal of molecular signaling 5, 1-9, 2010 | 143 | 2010 |
Overnutrition and maternal obesity in sheep pregnancy alter the JNK-IRS-1 signaling cascades and cardiac function in the fetal heart J Wang, H Ma, C Tong, H Zhang, GB Lawlis, Y Li, M Zang, J Ren, ... The FASEB Journal 24 (6), 2066, 2010 | 129 | 2010 |
Retinoic acid receptor β stimulates hepatic induction of fibroblast growth factor 21 to promote fatty acid oxidation and control whole-body energy homeostasis in mice Y Li, K Wong, K Walsh, B Gao, M Zang Journal of Biological Chemistry 288 (15), 10490-10504, 2013 | 109 | 2013 |
The Thromboxane A2 Receptor Antagonist S18886 Prevents Enhanced Atherogenesis Caused by Diabetes Mellitus A Zuccollo, C Shi, R Mastroianni, KA Maitland-Toolan, RM Weisbrod, ... Circulation 112 (19), 3001-3008, 2005 | 104 | 2005 |
DEP domain–containing mTOR–interacting protein suppresses lipogenesis and ameliorates hepatic steatosis and acute‐on‐chronic liver injury in alcoholic liver disease H Chen, F Shen, A Sherban, A Nocon, Y Li, H Wang, MJ Xu, X Rui, J Han, ... Hepatology 68 (2), 496-514, 2018 | 84 | 2018 |
Activation of sterol regulatory element binding protein and NLRP3 inflammasome in atherosclerotic lesion development in diabetic pigs Y Li, S Xu, B Jiang, RA Cohen, M Zang PloS one 8 (6), e67532, 2013 | 81 | 2013 |
Characterization of Ser338 phosphorylation for Raf-1 activation M Zang, J Gong, L Luo, J Zhou, X Xiang, W Huang, Q Huang, X Luo, ... Journal of Biological Chemistry 283 (46), 31429-31437, 2008 | 80 | 2008 |