| Efficacy and safety of RTS, S/AS01 malaria vaccine with or without a booster dose in infants and children in Africa: final results of a phase 3, individually randomised … S Rts Lancet 386 (9988), 31-45, 2015 | 2352* | 2015 |
| Mortality after fluid bolus in African children with severe infection K Maitland, S Kiguli, RO Opoka, C Engoru, P Olupot-Olupot, SO Akech, ... New England Journal of Medicine 364 (26), 2483-2495, 2011 | 1853 | 2011 |
| Efficacy of RTS, S/AS01E vaccine against malaria in children 5 to 17 months of age P Bejon, J Lusingu, A Olotu, A Leach, M Lievens, J Vekemans, S Mshamu, ... New England Journal of Medicine 359 (24), 2521-2532, 2008 | 544 | 2008 |
| Health research capacity development in low and middle income countries: reality or rhetoric? A systematic meta-narrative review of the qualitative literature SRP Franzen, C Chandler, T Lang BMJ open 7 (1), e012332, 2017 | 335 | 2017 |
| Efficacy of RTS, S/AS01E malaria vaccine and exploratory analysis on anti-circumsporozoite antibody titres and protection in children aged 5–17 months in Kenya and Tanzania: a … A Olotu, J Lusingu, A Leach, M Lievens, J Vekemans, S Msham, T Lang, ... The Lancet infectious diseases 11 (2), 102-109, 2011 | 225 | 2011 |
| Safety and immunogenicity of a new tuberculosis vaccine, MVA85A, in healthy adults in South Africa T Hawkridge, TJ Scriba, S Gelderbloem, E Smit, M Tameris, S Moyo, ... The Journal of infectious diseases 198 (4), 544-552, 2008 | 223 | 2008 |
| Experimental treatment of Ebola virus disease with TKM-130803: a single-arm phase 2 clinical trial J Dunning, F Sahr, A Rojek, F Gannon, G Carson, B Idriss, T Massaquoi, ... PLoS medicine 13 (4), e1001997, 2016 | 195 | 2016 |
| A phase 2b randomised trial of the candidate malaria vaccines FP9 ME-TRAP and MVA ME-TRAP among children in Kenya P Bejon, J Mwacharo, O Kai, T Mwangi, P Milligan, S Todryk, S Keating, ... PLoS clinical trials 1 (6), e29, 2006 | 189 | 2006 |
| Clinical trials have gone global: is this a good thing? T Lang, S Siribaddana PLoS medicine 9 (6), e1001228, 2012 | 169 | 2012 |
| Comparison of chlorproguanil-dapsone with sulfadoxine-pyrimethamine for the treatment of uncomplicated falciparum malaria in young African children: double-blind randomised … A Alloueche, W Bailey, S Barton, J Bwika, P Chimpeni, CO Falade, ... The Lancet 363 (9424), 1843-1848, 2004 | 127 | 2004 |
| The induction and persistence of T cell IFN-γ responses after vaccination or natural exposure is suppressed by Plasmodium falciparum P Bejon, J Mwacharo, O Kai, S Todryk, S Keating, B Lowe, T Lang, ... The Journal of Immunology 179 (6), 4193-4201, 2007 | 117 | 2007 |
| Advancing global health research through digital technology and sharing data T Lang Science 331 (6018), 714-717, 2011 | 115 | 2011 |
| Open source clinical science for emerging infections JW Dunning, L Merson, GGU Rohde, Z Gao, MG Semple, D Tran, ... The Lancet. Infectious diseases 14 (1), 8, 2013 | 114 | 2013 |
| Experimental treatment of Ebola virus disease with brincidofovir J Dunning, SB Kennedy, A Antierens, J Whitehead, I Ciglenecki, ... PloS one 11 (9), e0162199, 2016 | 107 | 2016 |
| Clinical research in resource-limited settings: enhancing research capacity and working together to make trials less complicated TA Lang, NJ White, TT Hien, JJ Farrar, NPJ Day, R Fitzpatrick, BJ Angus, ... PLoS neglected tropical diseases 4 (6), e619, 2010 | 104 | 2010 |
| The development of Lapdap, an affordable new treatment for malaria T Lang, B Greenwood The Lancet infectious diseases 3 (3), 162-168, 2003 | 95 | 2003 |
| The challenges and opportunities of conducting a clinical trial in a low resource setting: the case of the Cameroon mobile phone SMS (CAMPS) trial, an investigator initiated trial L Mbuagbaw, L Thabane, P Ongolo-Zogo, T Lang Trials 12, 1-7, 2011 | 93 | 2011 |
| Use of deferred consent for severely ill children in a multi-centre phase III trial K Maitland, S Molyneux, M Boga, S Kiguli, T Lang Trials 12, 1-6, 2011 | 92 | 2011 |
| Strategies for developing sustainable health research capacity in low and middle-income countries: a prospective, qualitative study investigating the barriers and enablers to … SRP Franzen, C Chandler, S Siribaddana, J Atashili, B Angus, T Lang BMJ open 7 (10), e017246, 2017 | 89 | 2017 |
| Making randomised trials more efficient: report of the first meeting to discuss the Trial Forge platform S Treweek, DG Altman, P Bower, M Campbell, I Chalmers, S Cotton, ... Trials 16, 1-10, 2015 | 88 | 2015 |
