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Matthew A Child
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A multifunctional serine protease primes the malaria parasite for red blood cell invasion
K Koussis, C Withers‐Martinez, S Yeoh, M Child, F Hackett, E Knuepfer, ...
The EMBO journal 28 (6), 725-735, 2009
2132009
A small-molecule antivirulence agent for treating Clostridium difficile infection
KO Bender, M Garland, JA Ferreyra, AJ Hryckowian, MA Child, AW Puri, ...
Science translational medicine 7 (306), 306ra148-306ra148, 2015
1342015
Rapid evolution of blood-brain-barrier-penetrating AAV capsids by RNA-driven biopanning
M Nonnenmacher, W Wang, MA Child, XQ Ren, C Huang, AZ Ren, ...
Molecular Therapy-Methods & Clinical Development 20, 366-378, 2021
1002021
Global analysis of palmitoylated proteins in Toxoplasma gondii
IT Foe, MA Child, JD Majmudar, S Krishnamurthy, WA van der Linden, ...
Cell host & microbe 18 (4), 501-511, 2015
842015
Activity-and reactivity-based proteomics: Recent technological advances and applications in drug discovery
HJ Benns, CJ Wincott, EW Tate, MA Child
Current Opinion in Chemical Biology 60, 20-29, 2021
822021
Proteases as regulators of pathogenesis: examples from the Apicomplexa
H Li, MA Child, M Bogyo
Biochimica et Biophysica Acta (BBA)-Proteins and Proteomics 1824 (1), 177-185, 2012
792012
The Calcium-Dependent Protein Kinase 3 of Toxoplasma Influences Basal Calcium Levels and Functions beyond Egress as Revealed by Quantitative …
M Treeck, JL Sanders, RY Gaji, KA LaFavers, MA Child, G Arrizabalaga, ...
PLoS pathogens 10 (6), e1004197, 2014
692014
Small-molecule inhibition of a depalmitoylase enhances Toxoplasma host-cell invasion
MA Child, CI Hall, JR Beck, LO Ofori, VE Albrow, M Garland, PW Bowyer, ...
Nature chemical biology 9 (10), 651-656, 2013
692013
Elucidating the interplay between IgG-Fc valency and FcγR activation for the design of immune complex inhibitors
DF Ortiz, JC Lansing, L Rutitzky, E Kurtagic, T Prod’homme, A Choudhury, ...
Science translational medicine 8 (365), 365ra158-365ra158, 2016
682016
Chemical genetic screen identifies Toxoplasma DJ-1 as a regulator of parasite secretion, attachment, and invasion
CI Hall, ML Reese, E Weerapana, MA Child, PW Bowyer, VE Albrow, ...
Proceedings of the National Academy of Sciences 108 (26), 10568-10573, 2011
672011
Regulated maturation of malaria merozoite surface protein‐1 is essential for parasite growth
MA Child, C Epp, H Bujard, MJ Blackman
Molecular microbiology 78 (1), 187-202, 2010
582010
Development of an activity-based probe for acyl-protein thioesterases
M Garland, CJ Schulze, IT Foe, WA van der Linden, MA Child, M Bogyo
PloS one 13 (1), e0190255, 2018
202018
Molecular determinants for subcellular trafficking of the malarial sheddase PfSUB2
MA Child, PK Harris, CR Collins, C Withers‐Martinez, S Yeoh, ...
Traffic 14 (10), 1053-1064, 2013
182013
CRISPR-based oligo recombineering prioritizes apicomplexan cysteines for drug discovery
HJ Benns, M Storch, JA Falco, FR Fisher, F Tamaki, E Alves, CJ Wincott, ...
Nature Microbiology 7 (11), 1891-1905, 2022
162022
Toxoplasma DJ-1 regulates organelle secretion by a direct interaction with calcium-dependent protein kinase 1
MA Child, M Garland, I Foe, P Madzelan, M Treeck, WA Van Der Linden, ...
MBio 8 (1), 10.1128/mbio. 02189-16, 2017
142017
Activity-based protein profiling for the study of parasite biology
HJ Benns, EW Tate, MA Child
Activity-Based Protein Profiling, 155-174, 2019
122019
Design and synthesis of activity-based probes and inhibitors for bleomycin hydrolase
WA van der Linden, E Segal, MA Child, A Byzia, M Drąg, M Bogyo
Chemistry & biology 22 (8), 995-1001, 2015
112015
An Extracellular Redox Signal Triggers Calcium Release and Impacts the Asexual Development of Toxoplasma gondii
E Alves, HJ Benns, L Magnus, C Dominicus, T Dobai, J Blight, CJ Wincott, ...
Frontiers in Cellular and Infection Microbiology 11, 728425, 2021
102021
Cellular barcoding of protozoan pathogens reveals the within-host population dynamics of Toxoplasma gondii host colonization
CJ Wincott, G Sritharan, HJ Benns, D May, C Gilabert-Carbajo, M Bunyan, ...
Cell Reports Methods 2 (8), 2022
92022
Malaria parasite evades mosquito immunity by glutaminyl cyclase–mediated posttranslational protein modification
SK Kolli, A Molina-Cruz, T Araki, FJA Geurten, J Ramesar, ...
Proceedings of the National Academy of Sciences 119 (35), e2209729119, 2022
72022
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