David T. Ting
David T. Ting
Massachusetts General Hospital
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Circulating breast tumor cells exhibit dynamic changes in epithelial and mesenchymal composition
M Yu, A Bardia, BS Wittner, SL Stott, ME Smas, DT Ting, SJ Isakoff, ...
science 339 (6119), 580-584, 2013
Circulating tumor cell clusters are oligoclonal precursors of breast cancer metastasis
N Aceto, A Bardia, DT Miyamoto, MC Donaldson, BS Wittner, JA Spencer, ...
Cell 158 (5), 1110-1122, 2014
Inertial focusing for tumor antigen–dependent and–independent sorting of rare circulating tumor cells
E Ozkumur, AM Shah, JC Ciciliano, BL Emmink, DT Miyamoto, E Brachtel, ...
Science translational medicine 5 (179), 179ra47-179ra47, 2013
Ex vivo culture of circulating breast tumor cells for individualized testing of drug susceptibility
M Yu, A Bardia, N Aceto, F Bersani, MW Madden, MC Donaldson, ...
science 345 (6193), 216-220, 2014
Radiological and surgical implications of neoadjuvant treatment with FOLFIRINOX for locally advanced and borderline resectable pancreatic cancer
CR Ferrone, G Marchegiani, TS Hong, DP Ryan, V Deshpande, ...
Annals of surgery 261 (1), 12-17, 2015
A microfluidic device for label-free, physical capture of circulating tumor cell clusters
AF Sarioglu, N Aceto, N Kojic, MC Donaldson, M Zeinali, B Hamza, ...
Nature methods 12 (7), 685-691, 2015
RNA-Seq of single prostate CTCs implicates noncanonical Wnt signaling in antiandrogen resistance
DT Miyamoto, Y Zheng, BS Wittner, RJ Lee, H Zhu, KT Broderick, R Desai, ...
Science 349 (6254), 1351-1356, 2015
Aberrant overexpression of satellite repeats in pancreatic and other epithelial cancers
DT Ting, D Lipson, S Paul, BW Brannigan, S Akhavanfard, EJ Coffman, ...
science 331 (6017), 593-596, 2011
RNA sequencing of pancreatic circulating tumour cells implicates WNT signalling in metastasis
M Yu, DT Ting, SL Stott, BS Wittner, F Ozsolak, S Paul, JC Ciciliano, ...
Nature 487 (7408), 510-513, 2012
Poly (lactic acid)-poly (ethylene glycol) nanoparticles as new carriers for the delivery of plasmid DNA
C Perez, A Sanchez, D Putnam, D Ting, R Langer, MJ Alonso
Journal of controlled Release 75 (1-2), 211-224, 2001
Single-cell RNA sequencing identifies extracellular matrix gene expression by pancreatic circulating tumor cells
DT Ting, BS Wittner, M Ligorio, NV Jordan, AM Shah, DT Miyamoto, ...
Cell reports 8 (6), 1905-1918, 2014
Stromal microenvironment shapes the intratumoral architecture of pancreatic cancer
M Ligorio, S Sil, J Malagon-Lopez, LT Nieman, S Misale, M Di Pilato, ...
Cell 178 (1), 160-175. e27, 2019
Total neoadjuvant therapy with FOLFIRINOX in combination with losartan followed by chemoradiotherapy for locally advanced pancreatic cancer: a phase 2 clinical trial
JE Murphy, JY Wo, DP Ryan, JW Clark, W Jiang, BY Yeap, LC Drapek, ...
JAMA oncology 5 (7), 1020-1027, 2019
EWS-FLI1 utilizes divergent chromatin remodeling mechanisms to directly activate or repress enhancer elements in Ewing sarcoma
N Riggi, B Knoechel, SM Gillespie, E Rheinbay, G Boulay, ML Suvā, ...
Cancer cell 26 (5), 668-681, 2014
Liquid versus tissue biopsy for detecting acquired resistance and tumor heterogeneity in gastrointestinal cancers
AR Parikh, I Leshchiner, L Elagina, L Goyal, C Levovitz, G Siravegna, ...
Nature medicine 25 (9), 1415-1421, 2019
HER2 expression identifies dynamic functional states within circulating breast cancer cells
NV Jordan, A Bardia, BS Wittner, C Benes, M Ligorio, Y Zheng, M Yu, ...
Nature 537 (7618), 102-106, 2016
Androgen receptor signaling in circulating tumor cells as a marker of hormonally responsive prostate cancer
DT Miyamoto, RJ Lee, SL Stott, DT Ting, BS Wittner, M Ulman, ME Smas, ...
Cancer discovery 2 (11), 995-1003, 2012
Molecularly engineered poly (ortho ester) microspheres for enhanced delivery of DNA vaccines
C Wang, Q Ge, D Ting, D Nguyen, HR Shen, J Chen, HN Eisen, J Heller, ...
Nature materials 3 (3), 190-196, 2004
SARS-CoV-2 can infect the placenta and is not associated with specific placental histopathology: a series of 19 placentas from COVID-19-positive mothers
JL Hecht, B Quade, V Deshpande, M Mino-Kenudson, DT Ting, N Desai, ...
Modern Pathology 33 (11), 2092-2103, 2020
TAS-120 overcomes resistance to ATP-competitive FGFR inhibitors in patients with FGFR2 fusion–positive intrahepatic cholangiocarcinoma
L Goyal, L Shi, LY Liu, F Fece de la Cruz, JK Lennerz, S Raghavan, ...
Cancer discovery 9 (8), 1064-1079, 2019
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