Yuzhuo Wang, Ph.D. FCAHS

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Colin Collins, PhDProfessor of Urologic Sciences, University of British Columbia and Vancouver Prostate CentreVerified email at prostatecentre.com
Martin GleaveProfessor of Urologic Sciences, University of British ColumbiaVerified email at ubc.ca
Crea FrancescoSenior Lecturer in Cancer Genetics, The Open UniversityVerified email at open.ac.uk
Ladan Fazli MDUniversity of British Columbia - Vancouver Prostate CancerVerified email at prostatecentre.com
Simon W. HaywardDirector, Cancer Biology. NorthShore University HealthSystemVerified email at northshore.org
Anne HaegertVancouver Prostate CentreVerified email at prostatecentre.com
Himisha BeltranDana Farber Cancer InstituteVerified email at dfci.harvard.edu
Alexander WyattAssociate Professor, University of British ColumbiaVerified email at prostatecentre.com
Noushin Nabavi, PhDUniversity of British Columbia | Vancouver Prostate CentreVerified email at prostatecentre.com
Amina ZoubeidiUniversity of British ColumbiaVerified email at prostatecentre.com
Xinpei CiPrincess Margaret Cancer CentreVerified email at uhnresearch.ca
Mark A RubinProfessor & Director Department for BioMedical Research, University of BernVerified email at dbmr.unibe.ch
Abhijit ParoliaResearch Investigator & incoming Asst. Professor of Pathology, University of Michigan Medical SchoolVerified email at umich.edu
Takeshi KuritaTokyo Medical and Dental UniversityVerified email at tmd.ac.jp
Stas VolikScientist, Vancouver Prostate CentreVerified email at prostatecentre.com
Robert H. BellVancouver Prostate CentreVerified email at prostatecentre.com
Gail RisbridgerMonash UniversityVerified email at monash.edu
Xuesen DongUniversity of British ColumbiaVerified email at prostatecentre.com
Marianne SadarDistinguished Scientist, Michael Smith Genome Sciences Centre, BC Cancer Agency ProfessorVerified email at bcgsc.ca
David HuntsmanBC Cancer AgencyVerified email at bccancer.bc.ca

Yuzhuo Wang, Ph.D. FCAHS

Professor of Urologic Sciences, UBC

Verified email at bccrc.ca - Homepage

Prostate Xenograft PDX Therapeutic Development


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Molecular characterization of neuroendocrine prostate cancer and identification of new drug targets H Beltran, DS Rickman, K Park, SS Chae, A Sboner, TY MacDonald, ... Cancer discovery 1 (6), 487-495, 2011	922	2011
Dynamics of genomic clones in breast cancer patient xenografts at single-cell resolution P Eirew, A Steif, J Khattra, G Ha, D Yap, H Farahani, K Gelmon, S Chia, ... Nature 518 (7539), 422-426, 2015	652	2015
Regression of castrate-recurrent prostate cancer by a small-molecule inhibitor of the amino-terminus domain of the androgen receptor RJ Andersen, NR Mawji, J Wang, G Wang, S Haile, JK Myung, K Watt, ... Cancer cell 17 (6), 535-546, 2010	603	2010
Androgen receptor gene aberrations in circulating cell-free DNA: biomarkers of therapeutic resistance in castration-resistant prostate cancer AA Azad, SV Volik, AW Wyatt, A Haegert, S Le Bihan, RH Bell, ... Clinical cancer research 21 (10), 2315-2324, 2015	512	2015
Role of the stromal microenvironment in carcinogenesis of the prostate GR Cunha, SW Hayward, YZ Wang, WA Ricke Prostate and Renal Cancer, Benign Prostatic Hyperplasia, Erectile …, 2003	475	2003
The x cystine/glutamate antiporter: A potential target for therapy of cancer and other diseases M Lo, YZ Wang, PW Gout Journal of cellular physiology 215 (3), 593-602, 2008	436	2008
Malignant transformation in a nontumorigenic human prostatic epithelial cell line SW Hayward, Y Wang, M Cao, YK Hom, B Zhang, GD Grossfeld, ... Cancer research 61 (22), 8135-8142, 2001	421	2001
Hormonal, cellular, and molecular regulation of normal and neoplastic prostatic development GR Cunha, W Ricke, A Thomson, PC Marker, G Risbridger, SW Hayward, ... The Journal of steroid biochemistry and molecular biology 92 (4), 221-236, 2004	413	2004
Cell differentiation lineage in the prostate Y Wang, SW Hayward, M Cao, KA Thayer, GR Cunha Differentiation 68 (4-5), 270-279, 2001	399	2001
High fidelity patient-derived xenografts for accelerating prostate cancer discovery and drug development D Lin, AW Wyatt, H Xue, Y Wang, X Dong, A Haegert, R Wu, S Brahmbhatt, ... Cancer research 74 (4), 1272-1283, 2014	395	2014
Role of stroma in carcinogenesis of the prostate GR Cunha, SW Hayward, YZ Wang Differentiation: REVIEW 70 (9‐10), 473-485, 2002	348	2002
The master neural transcription factor BRN2 is an androgen receptor–suppressed driver of neuroendocrine differentiation in prostate cancer JL Bishop, D Thaper, S Vahid, A Davies, K Ketola, H Kuruma, R Jama, ... Cancer discovery 7 (1), 54-71, 2017	342	2017
Cancer‐generated lactic acid: a regulatory, immunosuppressive metabolite? SYC Choi, CC Collins, PW Gout, Y Wang The Journal of pathology 230 (4), 350-355, 2013	342	2013
Translational activation of HIF1α by YB-1 promotes sarcoma metastasis AM El-Naggar, CJ Veinotte, H Cheng, TGP Grunewald, GL Negri, ... Cancer cell 27 (5), 682-697, 2015	310	2015
Whole-exome sequencing of metastatic cancer and biomarkers of treatment response H Beltran, K Eng, JM Mosquera, A Sigaras, A Romanel, H Rennert, ... JAMA oncology 1 (4), 466-474, 2015	306	2015
Nkx3. 1 mutant mice recapitulate early stages of prostate carcinogenesis MJ Kim, R Bhatia-Gaur, WA Banach-Petrosky, N Desai, Y Wang, ... Cancer research 62 (11), 2999-3004, 2002	305	2002
YB-1 regulates stress granule formation and tumor progression by translationally activating G3BP1 SP Somasekharan, A El-Naggar, G Leprivier, H Cheng, S Hajee, ... Journal of Cell Biology 208 (7), 913-929, 2015	287	2015
MicroRNAs associated with metastatic prostate cancer A Watahiki, Y Wang, J Morris, K Dennis, HM O'Dwyer, M Gleave, PW Gout, ... PloS one 6 (9), e24950, 2011	269	2011
Prostatic hormonal carcinogenesis is mediated by in situ estrogen production and estrogen receptor alpha signaling WA Ricke, SJ McPherson, JJ Bianco, GR Cunha, Y Wang, GP Risbridger The FASEB journal 22 (5), 1512-1520, 2008	269	2008
Intrinsic BET inhibitor resistance in prostate cancer caused by SPOP mutation-mediated BET protein stabilization P Zhang, D Wang, Y Zhao, S Reng, K Gao, Z Ye, S Wang, CW Pan, Y Zhu, ... Nature Medicine 23 (9), 1055-1062, 2017	256*	2017

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