| Measuring and managing ratio compression for accurate iTRAQ/TMT quantification MM Savitski, T Mathieson, N Zinn, G Sweetman, C Doce, I Becher, ... Journal of proteome research 12 (8), 3586-3598, 2013 | 302 | 2013 |
| DMSO enhances electrospray response, boosting sensitivity of proteomic experiments H Hahne, F Pachl, B Ruprecht, SK Maier, S Klaeger, D Helm, G Médard, ... Nature methods 10 (10), 989-991, 2013 | 257 | 2013 |
| EED-targeted PROTACs degrade EED, EZH2, and SUZ12 in the PRC2 complex JHR Hsu, T Rasmusson, J Robinson, F Pachl, J Read, S Kawatkar, ... Cell chemical biology 27 (1), 41-46. e17, 2020 | 185 | 2020 |
| Proteolysis‐targeting chimeras in drug development: a safety perspective K Moreau, M Coen, AX Zhang, F Pachl, MP Castaldi, G Dahl, H Boyd, ... British journal of pharmacology 177 (8), 1709-1718, 2020 | 157 | 2020 |
| The timely deposition of callose is essential for cytokinesis in Arabidopsis K Thiele, G Wanner, V Kindzierski, G Jürgens, U Mayer, F Pachl, ... The Plant Journal 58 (1), 13-26, 2009 | 153 | 2009 |
| Optimized chemical proteomics assay for kinase inhibitor profiling G Médard, F Pachl, B Ruprecht, S Klaeger, S Heinzlmeir, D Helm, H Qiao, ... Journal of proteome research 14 (3), 1574-1586, 2015 | 150 | 2015 |
| Ion mobility tandem mass spectrometry enhances performance of bottom-up proteomics D Helm, JPC Vissers, CJ Hughes, H Hahne, B Ruprecht, F Pachl, A Grzyb, ... Molecular & Cellular Proteomics 13 (12), 3709-3715, 2014 | 127 | 2014 |
| Discovery of 5-{4-[(7-Ethyl-6-oxo-5,6-dihydro-1,5-naphthyridin-3-yl)methyl]piperazin-1-yl}-N-methylpyridine-2-carboxamide (AZD5305): A PARP1–DNA Trapper … JW Johannes, A Balazs, D Barratt, M Bista, MD Chuba, S Cosulich, ... Journal of Medicinal Chemistry 64 (19), 14498-14512, 2021 | 82 | 2021 |
| Mitotic arrest and slippage induced by pharmacological inhibition of Polo-like kinase 1 M Raab, A Krämer, S Hehlgans, M Sanhaji, E Kurunci-Csacsko, C Dötsch, ... Molecular oncology 9 (1), 140-154, 2015 | 59 | 2015 |
| Co‐immunoprecipitation‐based identification of putative BAX INHIBITOR‐1‐interacting proteins involved in cell death regulation and plant–powdery mildew interactions C Weis, S Pfeilmeier, E Glawischnig, E Isono, F Pachl, H Hahne, B Kuster, ... Molecular Plant Pathology 14 (8), 791-802, 2013 | 50 | 2013 |
| Novel Flp pilus biogenesis-dependent natural transformation A Angelov, P Bergen, F Nadler, P Hornburg, A Lichev, M Übelacker, ... Frontiers in Microbiology 6, 84, 2015 | 49 | 2015 |
| Discovery of proteolysis-targeting chimera molecules that selectively degrade the IRAK3 pseudokinase SL Degorce, O Tavana, E Banks, C Crafter, L Gingipalli, D Kouvchinov, ... Journal of Medicinal Chemistry 63 (18), 10460-10473, 2020 | 46 | 2020 |
| Characterization of a chemical affinity probe targeting Akt kinases F Pachl, P Plattner, B Ruprecht, G Medard, N Sewald, B Kuster Journal of Proteome Research 12 (8), 3792-3800, 2013 | 41 | 2013 |
| Software tools for MS-based quantitative proteomics: a brief overview S Lemeer, H Hahne, F Pachl, B Kuster Quantitative methods in proteomics, 489-499, 2012 | 41 | 2012 |
| Reduced mitochondrial mass and function add to age‐related susceptibility toward diet‐induced fatty liver in C57BL/6J mice K Lohr, F Pachl, A Moghaddas Gholami, KE Geillinger, H Daniel, B Kuster, ... Physiological reports 4 (19), e12988, 2016 | 40 | 2016 |
| Towards understanding male infertility after spinal cord injury using quantitative proteomics BF da Silva, C Meng, D Helm, F Pachl, J Schiller, E Ibrahim, CM Lynne, ... Molecular & Cellular Proteomics 15 (4), 1424-1434, 2016 | 33 | 2016 |
| Abstract LB-273: A head-to-head comparison of the properties of five clinical PARP inhibitors identifies new insights that can explain both the observed clinical efficacy and … E Leo, J Johannes, G Illuzzi, A Zhang, P Hemsley, MJ Bista, JP Orme, ... Cancer Research 78 (13_Supplement), LB-273-LB-273, 2018 | 26 | 2018 |
| Quantitative chemical proteomics reveals a Plk1 inhibitor-compromised cell death pathway in human cells M Raab, F Pachl, A Krämer, E Kurunci-Csacsko, C Dötsch, R Knecht, ... Cell research 24 (9), 1141-1145, 2014 | 21 | 2014 |
| Characterization of a high field O rbitrap mass spectrometer for proteome analysis F Pachl, B Ruprecht, S Lemeer, B Kuster Proteomics 13 (17), 2552-2562, 2013 | 20 | 2013 |
| Proteomic and metabolite profiling reveals profound structural and metabolic reorganization of adipocyte mitochondria in obesity T Schöttl, F Pachl, P Giesbertz, H Daniel, B Kuster, T Fromme, ... Obesity 28 (3), 590-600, 2020 | 16 | 2020 |
