DNA stretching induces Cas9 off-target activity MD Newton, BJ Taylor, RPC Driessen, L Roos, N Cvetesic, S Allyjaun, ... Nature structural & molecular biology 26 (3), 185-192, 2019 | 131 | 2019 |
Comparative genomics of 10 new Caenorhabditis species L Stevens, MA Félix, T Beltran, C Braendle, C Caurcel, S Fausett, D Fitch, ... Evolution Letters 3 (2), 217-236, 2019 | 117 | 2019 |
Mapping the sugar dependency for rational generation of a DNA-RNA hybrid-guided Cas9 endonuclease FO Rueda, M Bista, MD Newton, AU Goeppert, ME Cuomo, E Gordon, ... Nature Communications 8 (1), 1610, 2017 | 72 | 2017 |
Single-molecule analysis reveals cooperative stimulation of Rad51 filament nucleation and growth by mediator proteins O Belan, C Barroso, A Kaczmarczyk, R Anand, S Federico, N O’Reilly, ... Molecular cell 81 (5), 1058-1073. e7, 2021 | 67 | 2021 |
A conserved ATP-and Scc2/4-dependent activity for cohesin in tethering DNA molecules P Gutierrez-Escribano, MD Newton, A Llauró, J Huber, L Tanasie, J Davy, ... Science advances 5 (11), eaay6804, 2019 | 51 | 2019 |
HELQ is a dual-function DSB repair enzyme modulated by RPA and RAD51 R Anand, E Buechelmaier, O Belan, M Newton, A Vancevska, ... Nature 601 (7892), 268-273, 2022 | 44 | 2022 |
Unloading of homologous recombination factors is required for restoring double‐stranded DNA at damage repair loci Y Vasianovich, V Altmannova, O Kotenko, MD Newton, L Krejci, ... The EMBO journal 36 (2), 213-231, 2017 | 32 | 2017 |
Negative DNA supercoiling induces genome-wide Cas9 off-target activity MD Newton, M Losito, QM Smith, N Parnandi, BJ Taylor, P Akcakaya, ... Molecular Cell 83 (19), 3533-3545. e5, 2023 | 15 | 2023 |
Search and processing of Holliday junctions within long DNA by junction-resolving enzymes AP Kaczmarczyk, AC Déclais, MD Newton, SJ Boulton, DMJ Lilley, ... Nature Communications 13 (1), 5921, 2022 | 15 | 2022 |
A Minimal Load‐and‐Lock RuII Luminescent DNA Probe MD Newton, SD Fairbanks, JA Thomas, DS Rueda Angewandte Chemie 133 (38), 21120-21127, 2021 | 13 | 2021 |
Cas12a target search and cleavage on force-stretched DNA M Losito, QM Smith, MD Newton, ME Cuomo, DS Rueda Physical Chemistry Chemical Physics 23 (47), 26640-26644, 2021 | 12 | 2021 |
Generation of versatile ss-dsDNA hybrid substrates for single-molecule analysis O Belan, G Moore, A Kaczmarczyk, MD Newton, R Anand, SJ Boulton, ... STAR protocols 2 (2), 100588, 2021 | 10 | 2021 |
Rapid Clinical Diagnostic Viral Detection with Saliva by a Novel Single Step Nested Mango-NASBA Assay H Iino, A Abdolahzadeh, E Dolgosheina, P Poudevigne-Durance, ... Biophysical Journal 120 (3), 196a, 2021 | 2 | 2021 |
HLTF resolves G4s and promotes G4-induced replication fork slowing to maintain genome stability G Bai, T Endres, U Kühbacher, V Mengoli, BH Greer, EM Peacock, ... Molecular Cell 84 (16), 3044-3060. e11, 2024 | | 2024 |
Direct observation of Shelterin dynamics and T-loop formation at telomeres MD Newton, JS Lewis, R Anand, EP Holmes, ALB Pyne, SJ Boulton Biophysical Journal 122 (3), 9a-10a, 2023 | | 2023 |
CRISPR/Cas9 On-and Off-Target Activity Using Correlative Force and Fluorescence Single-Molecule Microscopy MD Newton, BJ Taylor, ME Cuomo, DS Rueda Optical Tweezers: Methods and Protocols, 349-378, 2022 | | 2022 |
Cas12a target search and cleavage on force stretched DNA M Losito, QM Smith, MD Newton, ME Cuomo, DS Rueda Biophysical Journal 121 (3), 288a, 2022 | | 2022 |
Finding and cleaving a holliday junction in long double-stranded DNA: a complete resolution reaction trajectory by single-molecule tracking A Kaczmarczyk, AC Déclais, MD Newton, DMJ Lilley, DS Rueda Biophysical Journal 121 (3), 23a, 2022 | | 2022 |
HELQ is a dual function DSB repair enzyme modulated by RPA and RAD51 S Boulton, R Anand, E Buechelmaier, O Belan, M Newton, A Vancevska, ... | | 2021 |
DNA Stretching and Supercoiling Induces Cas9 Off-Target Activity MD Newton, G King, BJ Taylor, EM Cuomo, DS Rueda Biophysical Journal 120 (3), 34a-35a, 2021 | | 2021 |