Titia K. Sixma
Titia K. Sixma
Division of Biochemistry, Netherlands Cancer Institute, Amsterdam
Verified email at
Cited by
Cited by
Crystal structure of an ACh-binding protein reveals the ligand-binding domain of nicotinic receptors
K Brejc, WJ Van Dijk, RV Klaassen, M Schuurmans, J Van Der Oost, ...
Nature 411 (6835), 269-276, 2001
A genomic and functional inventory of deubiquitinating enzymes
SMB Nijman, MPA Luna-Vargas, A Velds, TR Brummelkamp, AMG Dirac, ...
Cell 123 (5), 773-786, 2005
Nicotine and carbamylcholine binding to nicotinic acetylcholine receptors as studied in AChBP crystal structures
PHN Celie, SE van Rossum-Fikkert, WJ van Dijk, K Brejc, AB Smit, ...
Neuron 41 (6), 907-914, 2004
Structural basis for dual excitation and photoisomerization of the Aequorea victoria green fluorescent protein
K Brejc, TK Sixma, PA Kitts, SR Kain, RY Tsien, M Ormö, SJ Remington
Proceedings of the National Academy of Sciences 94 (6), 2306-2311, 1997
The crystal structure of DNA mismatch repair protein MutS binding to a G· T mismatch
MH Lamers, A Perrakis, JH Enzlin, HHK Winterwerp, N De Wind, ...
Nature 407 (6805), 711-717, 2000
Crystal structure of a cholera toxin-related heat-labile enterotoxin from E. coli
TK Sixma, SE Pronk, KH Kalk, ES Wartna, BAM van Zanten, B Witholt, ...
Nature 351 (6325), 371-377, 1991
RNF168 ubiquitinates K13-15 on H2A/H2AX to drive DNA damage signaling
F Mattiroli, JHA Vissers, WJ van Dijk, P Ikpa, E Citterio, W Vermeulen, ...
Cell 150 (6), 1182-1195, 2012
A glia-derived acetylcholine-binding protein that modulates synaptic transmission
AB Smit, NI Syed, D Schaap, J van Minnen, J Klumperman, KS Kits, ...
Nature 411 (6835), 261-268, 2001
wARP: improvement and extension of crystallographic phases by weighted averaging of multiple-refined dummy atomic models
A Perrakis, TK Sixma, KS Wilson, VS Lamzin
Acta Crystallographica Section D: Biological Crystallography 53 (4), 448-455, 1997
Structure and E3‐ligase activity of the Ring–Ring complex of Polycomb proteins Bmi1 and Ring1b
G Buchwald, P van der Stoop, O Weichenrieder, A Perrakis, ...
The EMBO journal 25 (11), 2465-2474, 2006
Histone H1 couples initiation and amplification of ubiquitin signalling after DNA damage
T Thorslund, A Ripplinger, S Hoffmann, T Wild, M Uckelmann, ...
Nature 527 (7578), 389-393, 2015
Refined structure of Escherichia coli heat-labile enterotoxin, a close relative of cholera toxin
TK Sixma, KH Kalk, BAM van Zanten, Z Dauter, J Kingma, B Witholt, ...
Journal of molecular biology 230 (3), 890-918, 1993
RNF8‐and RNF168‐dependent degradation of KDM4A/JMJD2A triggers 53BP1 recruitment to DNA damage sites
FA Mallette, F Mattiroli, G Cui, LC Young, MJ Hendzel, G Mer, TK Sixma, ...
The EMBO journal 31 (8), 1865-1878, 2012
Crystal structure of nicotinic acetylcholine receptor homolog AChBP in complex with an α-conotoxin PnIA variant
PHN Celie, IE Kasheverov, DY Mordvintsev, RC Hogg, P van Nierop, ...
Nature structural & molecular biology 12 (7), 582-588, 2005
Chemical synthesis of ubiquitin, ubiquitin‐based probes, and diubiquitin
F El Oualid, R Merkx, R Ekkebus, DS Hameed, JJ Smit, A de Jong, ...
Angewandte Chemie 122 (52), 10347-10351, 2010
Ubc9 sumoylation regulates SUMO target discrimination
P Knipscheer, A Flotho, H Klug, JV Olsen, WJ van Dijk, A Fish, ...
Molecular cell 31 (3), 371-382, 2008
SUMO modification of the ubiquitin-conjugating enzyme E2-25K
A Pichler, P Knipscheer, E Oberhofer, WJ Van Dijk, R Körner, JV Olsen, ...
Nature structural & molecular biology 12 (3), 264-269, 2005
Mechanism of USP7/HAUSP activation by its C-terminal ubiquitin-like domain and allosteric regulation by GMP-synthetase
AC Faesen, AMG Dirac, A Shanmugham, H Ovaa, A Perrakis, TK Sixma
Molecular cell 44 (1), 147-159, 2011
Structural determinants of selective α-conotoxin binding to a nicotinic acetylcholine receptor homolog AChBP
C Ulens, RC Hogg, PH Celie, D Bertrand, V Tsetlin, AB Smit, TK Sixma
Proceedings of the National Academy of Sciences 103 (10), 3615-3620, 2006
Lactose binding to heat-labile enterotoxin revealed by X-ray crystallography
TK Sixma, SME Pronk, KH Kalk, BAM van Zanten, AM Berghuis, WGJ Hol
Nature 355 (6360), 561-564, 1992
The system can't perform the operation now. Try again later.
Articles 1–20