Mapping of signaling networks through synthetic genetic interaction analysis by RNAi T Horn, T Sandmann, B Fischer, E Axelsson, W Huber, M Boutros Nature methods 8 (4), 341-346, 2011 | 209 | 2011 |
Clustering phenotype populations by genome‐wide RNAi and multiparametric imaging F Fuchs, G Pau, D Kranz, O Sklyar, C Budjan, S Steinbrink, T Horn, ... Molecular systems biology 6 (1), 370, 2010 | 208 | 2010 |
E-RNAi: a web application for the multi-species design of RNAi reagents—2010 update T Horn, M Boutros Nucleic acids research 38 (suppl_2), W332-W339, 2010 | 172 | 2010 |
GenomeRNAi: a database for cell-based and in vivo RNAi phenotypes, 2013 update EE Schmidt, O Pelz, S Buhlmann, G Kerr, T Horn, M Boutros Nucleic acids research 41 (D1), D1021-D1026, 2013 | 151 | 2013 |
A combined ex vivo and in vivo RNAi screen for notch regulators in Drosophila reveals an extensive notch interaction network A Saj, Z Arziman, D Stempfle, W Van Belle, U Sauder, T Horn, ... Developmental cell 18 (5), 862-876, 2010 | 151 | 2010 |
E-RNAi: a web application to design optimized RNAi constructs Z Arziman, T Horn, M Boutros Nucleic acids research 33 (suppl_2), W582-W588, 2005 | 115 | 2005 |
A map of directional genetic interactions in a metazoan cell B Fischer, T Sandmann, T Horn, M Billmann, V Chaudhary, W Huber, ... Elife 4, e05464, 2015 | 102 | 2015 |
Design and evaluation of genome-wide libraries for RNA interference screens T Horn, T Sandmann, M Boutros Genome biology 11, 1-12, 2010 | 99 | 2010 |
Selective FcγR co-engagement on APCs modulates the activity of therapeutic antibodies targeting T cell antigens JD Waight, D Chand, S Dietrich, R Gombos, T Horn, AM Gonzalez, ... Cancer Cell 33 (6), 1033-1047. e5, 2018 | 81 | 2018 |
The potent and selective cyclin-dependent kinases 4 and 6 inhibitor ribociclib (LEE011) is a versatile combination partner in preclinical cancer models S Kim, R Tiedt, A Loo, T Horn, S Delach, S Kovats, K Haas, BS Engstler, ... Oncotarget 9 (81), 35226, 2018 | 73 | 2018 |
Smed454 dataset: unravelling the transcriptome of Schmidtea mediterranea JF Abril, F Cebria, G Rodriguez-Esteban, T Horn, S Fraguas, B Calvo, ... BMC genomics 11, 1-19, 2010 | 71 | 2010 |
GenomeRNAi: a database for cell-based RNAi phenotypes T Horn, Z Arziman, J Berger, M Boutros Nucleic acids research 35 (suppl_1), D492-D497, 2007 | 50 | 2007 |
A Genome-Wide RNA Interference Screen Identifies a Differential Role of the Mediator CDK8 Module Subunits for GATA/ RUNX-Activated Transcription in Drosophila V Gobert, D Osman, S Bras, B Augé, M Boube, HM Bourbon, T Horn, ... Molecular and cellular biology 30 (11), 2837-2848, 2010 | 49 | 2010 |
GenomeRNAi: a database for cell-based RNAi phenotypes. 2009 update M Gilsdorf, T Horn, Z Arziman, O Pelz, E Kiner, M Boutros Nucleic acids research 38 (suppl_1), D448-D452, 2010 | 46 | 2010 |
High-order drug combinations are required to effectively kill colorectal cancer cells T Horn, S Ferretti, N Ebel, A Tam, S Ho, F Harbinski, A Farsidjani, ... Cancer research 76 (23), 6950-6963, 2016 | 44 | 2016 |
A genetic interaction map of cell cycle regulators M Billmann, T Horn, B Fischer, T Sandmann, W Huber, M Boutros Molecular biology of the cell 27 (8), 1397-1407, 2016 | 32 | 2016 |
Loss of PAFAH1B2 reduces amyloid-β generation by promoting the degradation of amyloid precursor protein C-terminal fragments RM Page, A Münch, T Horn, PH Kuhn, A Colombo, O Reiner, M Boutros, ... Journal of Neuroscience 32 (50), 18204-18214, 2012 | 25 | 2012 |
Extracting quantitative genetic interaction phenotypes from matrix combinatorial RNAi E Axelsson, T Sandmann, T Horn, M Boutros, W Huber, B Fischer BMC bioinformatics 12, 1-10, 2011 | 20 | 2011 |
Functional fingerprinting of human mesenchymal stem cells using high-throughput RNAi screening G Erdmann, M Suchanek, P Horn, F Graf, C Volz, T Horn, X Zhang, ... Genome medicine 7, 1-13, 2015 | 5 | 2015 |
Design of RNAi reagents for invertebrate model organisms and human disease vectors T Horn, M Boutros siRNA Design: Methods and Protocols, 315-346, 2013 | 4 | 2013 |