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Joshua S. Chappie
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The conserved KMN network constitutes the core microtubule-binding site of the kinetochore
IM Cheeseman, JS Chappie, EM Wilson-Kubalek, A Desai
Cell 127 (5), 983-997, 2006
11492006
Phylogenetic analysis and structural modeling of SARS-CoV-2 spike protein reveals an evolutionary distinct and proteolytically sensitive activation loop
JA Jaimes, NM André, JS Chappie, JK Millet, GR Whittaker
Journal of molecular biology 432 (10), 3309-3325, 2020
4972020
G domain dimerization controls dynamin's assembly-stimulated GTPase activity
JS Chappie, S Acharya, M Leonard, SL Schmid, F Dyda
Nature 465 (7297), 435-440, 2010
3392010
A pseudoatomic model of the dynamin polymer identifies a hydrolysis-dependent powerstroke
JS Chappie, JA Mears, S Fang, M Leonard, SL Schmid, RA Milligan, ...
Cell 147 (1), 209-222, 2011
2562011
The dynamin middle domain is critical for tetramerization and higher‐order self‐assembly
R Ramachandran, M Surka, JS Chappie, DM Fowler, TR Foss, BD Song, ...
The EMBO journal 26 (2), 559-566, 2007
2082007
Electrostatic tuning of ion conductance in potassium channels
CM Nimigean, JS Chappie, C Miller
Biochemistry 42 (31), 9263-9268, 2003
1442003
An intramolecular signaling element that modulates dynamin function in vitro and in vivo
JS Chappie, S Acharya, YW Liu, M Leonard, TJ Pucadyil, SL Schmid
Molecular biology of the cell 20 (15), 3561-3571, 2009
1132009
A dynamin mutant defines a superconstricted prefission state
AC Sundborger, S Fang, JA Heymann, P Ray, JS Chappie, JE Hinshaw
Cell reports 8 (3), 734-742, 2014
1032014
Building a fission machine–structural insights into dynamin assembly and activation
JS Chappie, F Dyda
Journal of cell science 126 (13), 2773-2784, 2013
782013
The structure of a eukaryotic nicotinic acid phosphoribosyltransferase reveals structural heterogeneity among type II PRTases
JS Chappie, JM Cànaves, GW Han, CL Rife, Q Xu, RC Stevens
Structure 13 (9), 1385-1396, 2005
462005
Endopeptidase regulation as a novel function of the Zur-dependent zinc starvation response
SG Murphy, L Alvarez, MC Adams, S Liu, JS Chappie, F Cava, T Dörr
MBio 10 (1), 10.1128/mbio. 02620-18, 2019
412019
Structural characterization of Class 2 OLD family nucleases supports a two-metal catalysis mechanism for cleavage
CJ Schiltz, A Lee, EA Partlow, CJ Hosford, JS Chappie
Nucleic Acids Research 47 (17), 9448-9463, 2019
362019
The structural biology of the dynamin‐related proteins: New insights into a diverse, multitalented family
MGJ Ford, JS Chappie
Traffic 20 (10), 717-740, 2019
332019
Diffusible signal factors act through AraC-type transcriptional regulators as chemical cues to repress virulence of enteric pathogens
EM Bosire, CR Eade, CJ Schiltz, AJ Reid, J Troutman, JS Chappie, ...
Infection and immunity 88 (10), 10.1128/iai. 00226-20, 2020
262020
Cyclin N-terminal domain-containing-1 coordinates meiotic crossover formation with cell-cycle progression in a cyclin-independent manner
S Gray, ER Santiago, JS Chappie, PE Cohen
Cell reports 32 (1), 2020
202020
A structural mechanism for phosphorylation-dependent inactivation of the AP2 complex
EA Partlow, RW Baker, GM Beacham, JS Chappie, AE Leschziner, ...
Elife 8, e50003, 2019
202019
The full-length structure of Thermus scotoductus OLD defines the ATP hydrolysis properties and catalytic mechanism of Class 1 OLD family nucleases
CJ Schiltz, MC Adams, JS Chappie
Nucleic Acids Research 48 (5), 2762-2776, 2020
192020
The amino acid linker between the endonuclease and helicase domains of adeno-associated virus type 5 Rep plays a critical role in DNA-dependent oligomerization
JE Maggin, JA James, JS Chappie, F Dyda, AB Hickman
Journal of virology 86 (6), 3337-3346, 2012
182012
The structure of the Thermococcus gammatolerans McrB N-terminal domain reveals a new mode of substrate recognition and specificity among McrB homologs
CJ Hosford, AQ Bui, JS Chappie
Journal of Biological Chemistry 295 (3), 743-756, 2020
162020
Structures of the fungal dynamin-related protein Vps1 reveal a unique, open helical architecture
NV Varlakhanova, FJD Alvarez, TM Brady, BA Tornabene, CJ Hosford, ...
Journal of Cell Biology 217 (10), 3608-3624, 2018
152018
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