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Pradeep Shrestha
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Local immunomodulation with Fas ligand-engineered biomaterials achieves allogeneic islet graft acceptance
DM Headen, KB Woodward, MM Coronel, P Shrestha, JD Weaver, ...
Nature materials 17 (8), 732-739, 2018
1522018
Rapid On-Demand Extracellular Vesicle Augmentation with Versatile Oligonucleotide Tethers
SS Yerneni, S Lathwal, P Shrestha, H Shirwan, K Matyjaszewski, L Weiss, ...
ACS nano 13 (9), 10555-10565, 2019
882019
Localized Immunomodulation with PD-L1 Results in Sustained Survival and Function of Allogeneic Islets without Chronic Immunosuppression
L Batra, P Shrestha, H Zhao, KB Woodward, A Togay, M Tan, ...
The Journal of Immunology 204 (10), 2840-2851, 2020
322020
Pancreatic islets engineered with a FasL protein induce systemic tolerance at the induction phase that evolves into long‐term graft‐localized immune privilege
KB Woodward, H Zhao, P Shrestha, L Batra, M Tan, O Grimany‐Nuno, ...
American Journal of Transplantation 20 (5), 1285-1295, 2020
242020
A Novel Form of 4-1BBL Prevents Cancer Development via Nonspecific Activation of CD4+ T and Natural Killer Cells
HB Barsoumian, L Batra, P Shrestha, WS Bowen, H Zhao, NK Egilmez, ...
Cancer Research 79 (4), 783-794, 2019
192019
The Innate Immune System in Cardiovascular Diseases and Its Role in Doxorubicin-Induced Cardiotoxicity
A Bhagat, P Shrestha, ES Kleinerman
International Journal of Molecular Sciences 23 (23), 14649, 2022
182022
Immune checkpoint CD47 molecule engineered islets mitigate instant blood‐mediated inflammatory reaction and show improved engraftment following intraportal transplantation
P Shrestha, L Batra, M Tariq Malik, M Tan, ES Yolcu, H Shirwan
American Journal of Transplantation 20 (10), 2703-2714, 2020
172020
Doxorubicin-induced cardiotoxicity is mediated by neutrophils through release of neutrophil elastase
A Bhagat, P Shrestha, P Jeyabal, Z Peng, SS Watowich, ES Kleinerman
Frontiers in Oncology, 4158, 0
10
The Transient Display of a Chimeric PD-L1 Protein on Pancreatic Islets Promotes Indefinite Survival in Allogeneic Recipients
L Batra, P Shrestha, ES Yolcu, H Zhao, WS Bowen, KB Woodward, ...
Transplantation 102, S455, 2018
22018
SA-FasL-engineered PEG microgels as a novel means of modulating immune response to allogeneic islet grafts
H Shirwan, KB Woodward, DM Headen, H Zhao, P Shrestha, M Tan, ...
The Journal of Immunology 200 (1 Supplement), 55.36-55.36, 2018
22018
Engineering donor lymphocytes with Fas ligand protein effectively prevents acute graft-versus-host disease
P Shrestha, A Turan, L Batra, AE Gulen, Z Sun, H Tan, N Askenasy, ...
Blood Advances 7 (10), 2181-2195, 2023
12023
A novel agonist of CD137 shows immunoprevention efficacy against various tumors by invoking an innate immune surveillance mechanism
H Shirwan, L Batra, Q Li, MT Malik, P Shrestha, N Egilmez, ES Yolcu
Cancer Research 82 (12_Supplement), 1422-1422, 2022
2022
MS-275 to modulate NK cell response against Osteosarcoma. Implication of the chemokines CXCL9/CXCL10
UN Asika, A Rupp Anjier, Y Yang, P Shrestha, A Bhagat, N Gordon
2022
ISLETS ENGINEERED WITH CD47 INNATE IMMUNE CHECKPOINT PROTEIN SHOW ENHANCED ENGRAFTMENT FOLLOWING INTRAPORTAL TRANSPLANTATION BY MITIGATING INSTANT BLOOD MEDIATED INFLAMMATORY …
P Shrestha, L Batra, MT Malik, M Tan, E Yolcu, H Shirwan
Transplantation, S11, 2020
2020
IMMUNOMODULATION WITH SA-PDL1 PROTEIN ON PANCREATIC ISLETS PROMOTES INDEFINITE GRAFT SURVIVAL IN ALLOGENEIC RECIPIENTS
L Batra, P Shrestha, H Zhao, K Woodward, A Togay, M Tan, ...
Transplantation 104 (S3), 2020
2020
SA-4-1BBL as a novel agonist of CD137 has immunoprevention efficacy against various tumor types
H Shirwan, L Batra, MT Malik, P Shrestha, JL Hawthorne, ES Yolcu
Cancer Research 80 (16_Supplement), 4516-4516, 2020
2020
Immune Checkpoint PD-L1 Pathway as an Effective Platform for Localized Immunomodulation to Attain Indefinite Allogeneic Islet Graft Survival
L Batra, P Shrestha, H Zhao, KB Woodward, M Tan, OG Nuno, A Togay, ...
AMERICAN JOURNAL OF TRANSPLANTATION 20, 355-355, 2020
2020
CD47 Innate Immune Checkpoint Enhances Islet Engraftment Following Intraportal Transplantation by Mitigating Instant Blood Mediated Inflammatory Reaction
P Shrestha, L Batra, MT Malik, M Tan, ES Yolcu, H Shirwan
AMERICAN JOURNAL OF TRANSPLANTATION 20, 738-739, 2020
2020
Transient display of chimeric proteins on biological surfaces as an effective strategy for modulations of innate and adaptive immune responses.
P Shrestha
2020
A novel form of 4-1BB agonist shows robust immune protection against various tumor types through CD4+ memory-like T and NK cell axis
H Shirwan, HB Barsoumian, L Batra, P Shrestha, WS Bowen, H Zhao, ...
Cancer Research 79 (13_Supplement), 4145-4145, 2019
2019
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