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John Chappell
John Chappell
Associate Professor, Fralin Biomedical Research Institute at VTC
Verified email at vt.edu
Title
Cited by
Cited by
Year
Local guidance of emerging vessel sprouts requires soluble Flt-1.
JC Chappell, SM Taylor, N Ferrara, VL Bautch
Developmental Cell 17 (3), 377-386, 2009
2652009
The VEGF receptor Flt-1 spatially modulates Flk-1 signaling and blood vessel branching
NC Kappas, G Zeng, JC Chappell, JB Kearney, S Hazarika, KG Kallianos, ...
The Journal of cell biology 181 (5), 847-858, 2008
2172008
Influence of injection site, microvascular pressureand ultrasound variables on microbubble-mediated delivery of microspheres to muscle
J Song, JC Chappell, M Qi, EJ VanGieson, S Kaul, RJ Price
Journal of the American College of Cardiology 39 (4), 726-731, 2002
1622002
Regulation of blood vessel sprouting
JC Chappell, DM Wiley, VL Bautch
Seminars in cell & developmental biology 22 (9), 1005-1011, 2011
1062011
Targeted delivery of nanoparticles bearing fibroblast growth factor‐2 by ultrasonic microbubble destruction for therapeutic arteriogenesis
JC Chappell, J Song, CW Burke, AL Klibanov, RJ Price
Small 4 (10), 1769-1777, 2008
1002008
Hypoxia, angiogenesis, and metabolism in the hereditary kidney cancers
JC Chappell, LB Payne, WK Rathmell
The Journal of clinical investigation 129 (2), 442-451, 2019
822019
Vascular development: genetic mechanisms and links to vascular disease
JC Chappell, VL Bautch
Current topics in developmental biology 90, 43-72, 2010
732010
Excess vascular endothelial growth factor-A disrupts pericyte recruitment during blood vessel formation
J Darden, LB Payne, H Zhao, JC Chappell
Angiogenesis 22, 167-183, 2019
692019
Flt-1 (vascular endothelial growth factor receptor-1) is essential for the vascular endothelial growth factor–notch feedback loop during angiogenesis
JC Chappell, KP Mouillesseaux, VL Bautch
Arteriosclerosis, thrombosis, and vascular biology 33 (8), 1952-1959, 2013
622013
How blood vessel networks are made and measured
JC Chappell, DM Wiley, VL Bautch
Cells Tissues Organs 195 (1-2), 94-107, 2011
622011
The pericyte microenvironment during vascular development
LB Payne, H Zhao, CC James, J Darden, D McGuire, S Taylor, JW Smyth, ...
Microcirculation 26 (8), e12554, 2019
572019
Flt-1 (VEGFR-1) coordinates discrete stages of blood vessel formation
JC Chappell, JG Cluceru, JE Nesmith, KP Mouillesseaux, VB Bradley, ...
Cardiovascular research 111 (1), 84-93, 2016
572016
Blood vessel anastomosis is spatially regulated by Flt1 during angiogenesis
JE Nesmith, JC Chappell, JG Cluceru, VL Bautch
Development 144 (5), 889-896, 2017
542017
Specific labeling of synaptic schwann cells reveals unique cellular and molecular features
R Castro, T Taetzsch, SK Vaughan, K Godbe, J Chappell, RE Settlage, ...
Elife 9, e56935, 2020
522020
Ultrasound-microbubble-induced neovascularization in mouse skeletal muscle
JC Chappell, AL Klibanov, RJ Price
Ultrasound in medicine & biology 31 (10), 1411-1422, 2005
492005
Computational modeling of interacting VEGF and soluble VEGF receptor concentration gradients
YL Hashambhoy, JC Chappell, SM Peirce, VL Bautch, F Mac Gabhann
Frontiers in physiology 2, 10062, 2011
482011
Targeted therapeutic applications of acoustically active microspheres in the microcirculation
JC Chappell, RJ Price
Microcirculation 13 (1), 57-70, 2006
462006
Ultrasonic microbubble destruction stimulates therapeutic arteriogenesis via the CD18-dependent recruitment of bone marrow–derived cells
JC Chappell, J Song, AL Klibanov, RJ Price
Arteriosclerosis, thrombosis, and vascular biology 28 (6), 1117-1122, 2008
412008
Agent-based model of angiogenesis simulates capillary sprout initiation in multicellular networks
J Walpole, JC Chappell, JG Cluceru, F Mac Gabhann, VL Bautch, ...
Integrative biology 7 (9), 987-997, 2015
382015
Microvascular bioengineering: a focus on pericytes
H Zhao, JC Chappell
Journal of Biological Engineering 13 (1), 26, 2019
352019
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