Laura Machesky
Laura Machesky
Department of Biochemistry, University of Cambridge
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Cited by
Cited by
Scar1 and the related Wiskott–Aldrich syndrome protein, WASP, regulate the actin cytoskeleton through the Arp2/3 complex
LM Machesky, RH Insall
Current biology 8 (25), 1347-1356, 1998
Scar, a WASp-related protein, activates nucleation of actin filaments by the Arp2/3 complex
LM Machesky, RD Mullins, HN Higgs, DA Kaiser, L Blanchoin, RC May, ...
Proceedings of the National Academy of Sciences 96 (7), 3739-3744, 1999
The small GTPases Rho and Rac are required for the establishment of cadherin-dependent cell–cell contacts
VMM Braga, LM Machesky, A Hall, NA Hotchin
The Journal of cell biology 137 (6), 1421-1431, 1997
Phagocytosis and the actin cytoskeleton
RC May, LM Machesky
Journal of cell science 114 (6), 1061-1077, 2001
Purification of a cortical complex containing two unconventional actins from Acanthamoeba by affinity chromatography on profilin-agarose.
LM Machesky, SJ Atkinson, C Ampe, J Vandekerckhove, TD Pollard
The Journal of cell biology 127 (1), 107-115, 1994
Regulation of phospholipase C-γ1 by profilin and tyrosine phosphorylation
PJ Goldschmidt-Clermont, JW Kim, LM Machesky, SG Rhee, TD Pollard
Science 251 (4998), 1231-1233, 1991
Phosphatidylinositol 4, 5-bisphosphate induces actin-based movement of raft-enriched vesicles through WASP-Arp2/3
AL Rozelle, LM Machesky, M Yamamoto, MHE Driessens, RH Insall, ...
Current Biology 10 (6), 311-320, 2000
The actin-binding protein profilin binds to PIP2 and inhibits its hydrolysis by phospholipase C
PJ Goldschmidt-Clermont, LM Machesky, JJ Baldassare, TD Pollard
Science 247 (4950), 1575-1578, 1990
Role of actin polymerization and adhesion to extracellular matrix in Rac-and Rho-induced cytoskeletal reorganization
LM Machesky, A Hall
The Journal of cell biology 138 (4), 913-926, 1997
Actin dynamics at the leading edge: from simple machinery to complex networks
RH Insall, LM Machesky
Developmental cell 17 (3), 310-322, 2009
Rab27a is required for regulated secretion in cytotoxic T lymphocytes
JC Stinchcombe, DC Barral, EH Mules, S Booth, AN Hume, LM Machesky, ...
The Journal of cell biology 152 (4), 825-834, 2001
The Arp2/3 complex: a multifunctional actin organizer
LM Machesky, KL Gould
Current opinion in cell biology 11 (1), 117-121, 1999
Involvement of the Arp2/3 complex in phagocytosis mediated by FcγR or CR3
RC May, E Caron, A Hall, LM Machesky
Nature cell biology 2 (4), 246-248, 2000
Configuration of human dendritic cell cytoskeleton by Rho GTPases, the WAS protein, and differentiation
S Burns, AJ Thrasher, MP Blundell, L Machesky, GE Jones
Blood, The Journal of the American Society of Hematology 98 (4), 1142-1149, 2001
Signalling to actin assembly via the WASP (Wiskott-Aldrich syndrome protein)-family proteins and the Arp2/3 complex
TH Millard, SJ Sharp, LM Machesky
Biochemical Journal 380 (1), 1-17, 2004
Rho: a connection between membrane receptor signalling and the cytoskeleton
LM Machesky, A Hall
Trends in cell biology 6 (8), 304-310, 1996
Lamellipodia and filopodia in metastasis and invasion
LM Machesky
FEBS letters 582 (14), 2102-2111, 2008
Regulation of cadherin function by Rho and Rac: modulation by junction maturation and cellular context
VMM Braga, A Del Maschio, L Machesky, E Dejana
Molecular biology of the cell 10 (1), 9-22, 1999
The actin-bundling protein fascin stabilizes actin in invadopodia and potentiates protrusive invasion
A Li, JC Dawson, M Forero-Vargas, HJ Spence, X Yu, I König, K Anderson, ...
Current biology 20 (4), 339-345, 2010
Signaling to actin dynamics
LM Machesky, RH Insall
The Journal of cell biology 146 (2), 267-272, 1999
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