| Single-molecule visualization of fast polymerase turnover in the bacterial replisome JS Lewis, LM Spenkelink, S Jergic, EA Wood, E Monachino, NP Horan, ... Elife 6, e23932, 2017 | 126 | 2017 |
| The E. coli DNA replication fork JS Lewis, S Jergic, NE Dixon The Enzymes 39, 31-88, 2016 | 91* | 2016 |
| Tunability of DNA polymerase stability during eukaryotic DNA replication JS Lewis, LM Spenkelink, GD Schauer, O Yurieva, SH Mueller, ... Molecular cell 77 (1), 17-25. e5, 2020 | 87 | 2020 |
| Single-molecule visualization of Saccharomyces cerevisiae leading-strand synthesis reveals dynamic interaction between MTC and the replisome JS Lewis, LM Spenkelink, GD Schauer, FR Hill, RE Georgescu, ... Proceedings of the National Academy of Sciences 114 (40), 10630-10635, 2017 | 69 | 2017 |
| Nuclease dead Cas9 is a programmable roadblock for DNA replication KS Whinn, G Kaur, JS Lewis, GD Schauer, SH Mueller, S Jergic, ... Scientific reports 9 (1), 13292, 2019 | 65 | 2019 |
| Mechanism of replication origin melting nucleated by CMG helicase assembly JS Lewis, MH Gross, J Sousa, SS Henrikus, JF Greiwe, A Nans, ... Nature 606 (7916), 1007-1014, 2022 | 61 | 2022 |
| Spatial and temporal organization of RecA in the Escherichia coli DNA-damage response H Ghodke, BP Paudel, JS Lewis, S Jergic, K Gopal, ZJ Romero, EA Wood, ... Elife 8, e42761, 2019 | 60 | 2019 |
| Recycling of single-stranded DNA-binding protein by the bacterial replisome. LM Spenkelink, JS Lewis, S Jergic, ZQ Xu, A Robinson, NE Dixon, ... Nucleic Acid Research, gkz090, 2019 | 56 | 2019 |
| Replisome bypass of a protein-based R-loop block by Pif1 GD Schauer, LM Spenkelink, JS Lewis, O Yurieva, SH Mueller, ... Proceedings of the National Academy of Sciences 117 (48), 30354-30361, 2020 | 44 | 2020 |
| Shining a spotlight on DNA: single-molecule methods to visualise DNA G Kaur, JS Lewis, AM van Oijen Molecules 24 (3), 491, 2019 | 37 | 2019 |
| A primase-induced conformational switch controls the stability of the bacterial replisome E Monachino, S Jergic, JS Lewis, ZQ Xu, ATY Lo, VL O’Shea, JM Berger, ... Molecular cell 79 (1), 140-154. e7, 2020 | 23 | 2020 |
| Design of customizable long linear DNA substrates with controlled end modifications for single-molecule studies SH Mueller, LM Spenkelink, AM van Oijen, JS Lewis Analytical biochemistry 592, 113541, 2020 | 19 | 2020 |
| Caught in the act: structural dynamics of replication origin activation and fork progression JS Lewis, A Costa Biochemical Society Transactions 48 (3), 1057, 2020 | 18 | 2020 |
| The E. coli helicase does not use ATP during replication LM Spenkelink, RR Spinks, S Jergic, JS Lewis, NE Dixon, AM van Oijen bioRxiv, 2021.07. 07.451541, 2021 | 7 | 2021 |
| Unwinding of a eukaryotic origin of replication visualized by cryo-EM SS Henrikus, MH Gross, O Willhoft, T Pühringer, JS Lewis, AW McClure, ... Nature Structural & Molecular Biology, 1-12, 2024 | 5 | 2024 |
| Production of long linear DNA substrates with site-specific chemical lesions for single-molecule replisome studies G Kaur, LM Spenkelink, JS Lewis, S Jergic, NE Dixon, AM van Oijen Methods in enzymology 672, 299-315, 2022 | 5 | 2022 |
| Embracing Heterogeneity: Challenging the Paradigm of Replisomes as Deterministic Machines JS Lewis, AM van Oijen, LM Spenkelink Chemical Reviews 123 (23), 13419-13440, 2023 | 4 | 2023 |
| Direct observation of Shelterin dynamics and T-loop formation at telomeres MD Newton, JS Lewis, R Anand, EP Holmes, ALB Pyne, SJ Boulton Biophysical Journal 122 (3), 9a-10a, 2023 | | 2023 |
| Resolving the Gordian Knot: Srs2 Strips Intermediates Formed during Homologous Recombination H Ghodke, JS Lewis, AM van Oijen Trends in biochemical sciences 43 (3), 149-151, 2018 | | 2018 |
| Structural dynamics and protein interactions within the E. coli DNA polymerase III holoenzyme JS Lewis | | 2017 |
