Requirement for ceramide-initiated SAPK/JNK signalling in stress-induced apoptosis M Verheij, R Bose, XH Lin, B Yao, WD Jarvis, S Grant, MJ Birrer, E Szabo, ... Nature 380 (6569), 75-79, 1996 | 2272 | 1996 |
Genomic landscape of non-small cell lung cancer in smokers and never-smokers R Govindan, L Ding, M Griffith, J Subramanian, ND Dees, KL Kanchi, ... Cell 150 (6), 1121-1134, 2012 | 1377 | 2012 |
Whole-genome analysis informs breast cancer response to aromatase inhibition MJ Ellis, L Ding, D Shen, J Luo, VJ Suman, JW Wallis, BA Van Tine, ... Nature 486 (7403), 353-360, 2012 | 1222 | 2012 |
Ceramide synthase mediates daunorubicin-induced apoptosis: an alternative mechanism for generating death signals R Bose, M Verheij, A Haimovitz-Friedman, K Scotto, Z Fuks, R Kolesnick Cell 82 (3), 405-414, 1995 | 1081 | 1995 |
Activating HER2 mutations in HER2 gene amplification negative breast cancer R Bose, SM Kavuri, AC Searleman, W Shen, D Shen, DC Koboldt, ... Cancer discovery 3 (2), 224-237, 2013 | 920 | 2013 |
Endocrine-therapy-resistant ESR1 variants revealed by genomic characterization of breast-cancer-derived xenografts S Li, D Shen, J Shao, R Crowder, W Liu, A Prat, X He, S Liu, J Hoog, C Lu, ... Cell reports 4 (6), 1116-1130, 2013 | 712 | 2013 |
DGIdb: mining the druggable genome M Griffith, OL Griffith, AC Coffman, JV Weible, JF McMichael, NC Spies, ... Nature methods 10 (12), 1209, 2013 | 533 | 2013 |
Inhibition of the EGF receptor by binding of MIG6 to an activating kinase domain interface X Zhang, KA Pickin, R Bose, N Jura, PA Cole, J Kuriyan Nature 450 (7170), 741-744, 2007 | 400 | 2007 |
HER2 Activating Mutations Are Targets for Colorectal Cancer Treatment SM Kavuri, N Jain, F Galimi, F Cottino, SM Leto, G Migliardi, ... Cancer Discovery 5 (8), 832-841, 2015 | 308 | 2015 |
Phosphoproteomic analysis of Her2/neu signaling and inhibition R Bose, H Molina, AS Patterson, JK Bitok, B Periaswamy, JS Bader, ... Proceedings of the National Academy of Sciences 103 (26), 9773-9778, 2006 | 253 | 2006 |
Mechanism of activation and inhibition of the HER4/ErbB4 kinase C Qiu, MK Tarrant, SH Choi, A Sathyamurthy, R Bose, S Banjade, A Pal, ... Structure 16 (3), 460-467, 2008 | 215 | 2008 |
Human Proteinpedia enables sharing of human protein data S Mathivanan, M Ahmed, NG Ahn, H Alexandre, R Amanchy, PC Andrews, ... Nature biotechnology 26 (2), 164-167, 2008 | 179 | 2008 |
Exome sequencing and cis-regulatory mapping identify mutations in MAK, a gene encoding a regulator of ciliary length, as a cause of retinitis pigmentosa RK Özgül, AM Siemiatkowska, D Yücel, CA Myers, RWJ Collin, ... The American Journal of Human Genetics 89 (2), 253-264, 2011 | 121 | 2011 |
Quantitative proteomics with siRNA screening identifies novel mechanisms of trastuzumab resistance in HER2 amplified breast cancers AP Boyer, TS Collier, I Vidavsky, R Bose Molecular & Cellular Proteomics 12 (1), 180-193, 2013 | 108 | 2013 |
Analysis of the role of the C-terminal tail in the regulation of the epidermal growth factor receptor E Kovacs, R Das, Q Wang, TS Collier, A Cantor, Y Huang, K Wong, ... Molecular and Cellular Biology 35 (17), 3083-3102, 2015 | 102 | 2015 |
The ErbB kinase domain: structural perspectives into kinase activation and inhibition R Bose, X Zhang Experimental cell research 315 (4), 649-658, 2009 | 96 | 2009 |
HER2-Mutated Breast Cancer Responds to Treatment With Single-Agent Neratinib, a Second-Generation HER2/EGFR Tyrosine Kinase Inhibitor NE Ben-Baruch, R Bose, SM Kavuri, CX Ma, MJ Ellis Journal of the National Comprehensive Cancer Network 13 (9), 1061-1064, 2015 | 93 | 2015 |
Using multigene tests to select treatment for early-stage breast cancer R Goncalves, R Bose Journal of the National Comprehensive Cancer Network 11 (2), 174-182, 2013 | 76 | 2013 |
Her4 and Her2/neu tyrosine kinase domains dimerize and activate in a reconstituted in vitro system J Monsey, W Shen, P Schlesinger, R Bose Journal of Biological Chemistry 285 (10), 7035-7044, 2010 | 75 | 2010 |
Protein tyrosine kinase–substrate interactions R Bose, MA Holbert, KA Pickin, PA Cole Current opinion in structural biology 16 (6), 668-675, 2006 | 74 | 2006 |