| A functional screen implicates microRNA-138-dependent regulation of the depalmitoylation enzyme APT1 in dendritic spine morphogenesis G Siegel, G Obernosterer, R Fiore, M Oehmen, S Bicker, M Christensen, ... Nature cell biology 11 (6), 705-716, 2009 | 579 | 2009 |
| Target identification for small bioactive molecules: finding the needle in the haystack S Ziegler, V Pries, C Hedberg, H Waldmann Angewandte Chemie International Edition 52 (10), 2744-2792, 2013 | 507 | 2013 |
| Small-molecule inhibition of APT1 affects Ras localization and signaling FJ Dekker, O Rocks, N Vartak, S Menninger, C Hedberg, R Balamurugan, ... Nature chemical biology 6 (6), 449-456, 2010 | 413 | 2010 |
| The GDI-like solubilizing factor PDEδ sustains the spatial organization and signalling of Ras family proteins A Chandra, HE Grecco, V Pisupati, D Perera, L Cassidy, F Skoulidis, ... Nature cell biology 14 (2), 148-158, 2012 | 395 | 2012 |
| New Mechanistic Insights into the Iridium–Phosphanooxazoline‐Catalyzed Hydrogenation of Unfunctionalized Olefins: A DFT and Kinetic Study P Brandt, C Hedberg, PG Andersson Chemistry–A European Journal 9 (1), 339-347, 2003 | 191 | 2003 |
| Asymmetric Hydrogenation of Trisubstituted Olefins with Iridium− Phosphine Thiazole Complexes: A Further Investigation of the Ligand Structure C Hedberg, K Källström, P Brandt, LK Hansen, PG Andersson Journal of the American Chemical Society 128 (9), 2995-3001, 2006 | 180 | 2006 |
| Rationally designed ligands for asymmetric iridium-catalyzed hydrogenation of olefins K Källström, C Hedberg, P Brandt, A Bayer, PG Andersson Journal of the American Chemical Society 126 (44), 14308-14309, 2004 | 170 | 2004 |
| Mechanistic insights into the phosphine-free RuCp*-diamine-catalyzed hydrogenation of aryl ketones: Experimental and theoretical evidence for an alcohol-mediated dihydrogen … C Hedberg, K Källström, PI Arvidsson, P Brandt, PG Andersson Journal of the American Chemical Society 127 (43), 15083-15090, 2005 | 158 | 2005 |
| Identification of acyl protein thioesterases 1 and 2 as the cellular targets of the Ras‐signaling modulators palmostatin B and M M Rusch, TJ Zimmermann, M Bürger, FJ Dekker, K Görmer, G Triola, ... Angewandte Chemie-International Edition 50 (42), 9838, 2011 | 134 | 2011 |
| Choline-releasing glycerophosphodiesterase EDI3 drives tumor cell migration and metastasis JD Stewart, R Marchan, MS Lesjak, J Lambert, R Hergenroeder, JK Ellis, ... Proceedings of the National Academy of Sciences 109 (21), 8155-8160, 2012 | 131 | 2012 |
| The autodepalmitoylating activity of APT maintains the spatial organization of palmitoylated membrane proteins N Vartak, B Papke, HE Grecco, L Rossmannek, H Waldmann, C Hedberg, ... Biophysical journal 106 (1), 93-105, 2014 | 94 | 2014 |
| Iridium Catalysts with Chiral Imidazole‐Phosphine Ligands for Asymmetric Hydrogenation of Vinyl Fluorides and other Olefins P Kaukoranta, M Engman, C Hedberg, J Bergquist, PG Andersson Advanced Synthesis & Catalysis 350 (7‐8), 1168-1176, 2008 | 88 | 2008 |
| A Theoretical and Experimental Study of the Asymmetric Addition of Dialkylzinc to N‐(Diphenylphosphinoyl)benzalimine P Brandt, C Hedberg, K Lawonn, P Pinho, PG Andersson Chemistry–A European Journal 5 (6), 1692-1699, 1999 | 83 | 1999 |
| Development of highly potent inhibitors of the Ras‐targeting human acyl protein thioesterases based on substrate similarity design C Hedberg, FJ Dekker, M Rusch, S Renner, S Wetzel, N Vartak, ... Angewandte Chemie 123 (42), 10006-10011, 2011 | 81 | 2011 |
| Inhibiting the palmitoylation/depalmitoylation cycle selectively reduces the growth of hematopoietic cells expressing oncogenic Nras J Xu, C Hedberg, FJ Dekker, Q Li, KM Haigis, E Hwang, H Waldmann, ... Blood, The Journal of the American Society of Hematology 119 (4), 1032-1035, 2012 | 78 | 2012 |
| The mechanism of caseinolytic protease (ClpP) inhibition M Gersch, F Gut, VS Korotkov, J Lehmann, T Böttcher, M Rusch, ... Angewandte Chemie International Edition 52 (10), 3009-3014, 2013 | 67 | 2013 |
| Covalent protein labeling by enzymatic phosphocholination K Heller, P Ochtrop, MF Albers, FB Zauner, A Itzen, C Hedberg Angewandte Chemie international edition 54 (35), 10327-10330, 2015 | 62 | 2015 |
| An Optimised Small‐Molecule Stabiliser of the 14‐3‐3–PMA2 Protein–Protein Interaction A Richter, R Rose, C Hedberg, H Waldmann, C Ottmann Chemistry–A European Journal 18 (21), 6520-6527, 2012 | 62 | 2012 |
| Catalytic Asymmetric Total Synthesis of the Muscarinic Receptor Antagonist (R)‐Tolterodine C Hedberg, PG Andersson Advanced Synthesis & Catalysis 347 (5), 662-666, 2005 | 60 | 2005 |
| Iridium‐Catalysed Asymmetric Hydrogenation of Vinylsilanes as a Route to Optically Active Silanes K Källström, IJ Munslow, C Hedberg, PG Andersson Advanced Synthesis & Catalysis 348 (18), 2575-2578, 2006 | 58 | 2006 |
