SNARE-complex disassembly by NSF follows synaptic-vesicle fusion JT Littleton, RJO Barnard, SA Titus, J Slind, ER Chapman, B Ganetzky Proceedings of the National Academy of Sciences 98 (21), 12233-12238, 2001 | 174 | 2001 |
Concerted assembly and cloning of multiple DNA segments using in vitro site-specific recombination: functional analysis of multi-segment expression clones DL Cheo, SA Titus, DRN Byrd, JL Hartley, GF Temple, MA Brasch Genome research 14 (10b), 2111-2120, 2004 | 164 | 2004 |
Retrovirally Mediated Complementation of the glyBPhenotype: CLONING OF A HUMAN GENE ENCODING THE CARRIER FOR ENTRY OF FOLATES INTO MITOCHONDRIA SA Titus, RG Moran Journal of Biological Chemistry 275 (47), 36811-36817, 2000 | 164 | 2000 |
The Drosophila erg K+ channel polypeptide is encoded by the seizure locus SA Titus, JW Warmke, B Ganetzky Journal of Neuroscience 17 (3), 875-881, 1997 | 135 | 1997 |
The Eag Family of K+ Channels in Drosophila and Mammals B Ganetzky, GA Robertson, GF Wilson, MC Trudeau, SA Titus Annals of the New York Academy of Sciences 868 (1), 356-369, 1999 | 97 | 1999 |
A high-throughput imaging and nuclear segmentation analysis protocol for cleared 3D culture models ME Boutin, TC Voss, SA Titus, K Cruz-Gutierrez, S Michael, M Ferrer Scientific reports 8 (1), 11135, 2018 | 85 | 2018 |
Assessing inhibitors of mutant isocitrate dehydrogenase using a suite of pre-clinical discovery assays DJ Urban, NJ Martinez, MI Davis, KR Brimacombe, DM Cheff, TD Lee, ... Scientific reports 7 (1), 12758, 2017 | 81 | 2017 |
A mutation inactivating the mitochondrial inner membrane folate transporter creates a glycine requirement for survival of chinese hamster cells EA McCarthy, SA Titus, SM Taylor, C Jackson-Cook, RG Moran Journal of Biological Chemistry 279 (32), 33829-33836, 2004 | 78 | 2004 |
A new homogeneous high-throughput screening assay for profiling compound activity on the human ether-a-go-go-related gene channel SA Titus, D Beacham, SA Shahane, N Southall, M Xia, R Huang, ... Analytical biochemistry 394 (1), 30-38, 2009 | 70 | 2009 |
Exploration and optimization of substituted triazolothiadiazines and triazolopyridazines as PDE4 inhibitors AP Skoumbourdis, CA LeClair, E Stefan, AG Turjanski, W Maguire, ... Bioorganic & medicinal chemistry letters 19 (13), 3686-3692, 2009 | 63 | 2009 |
High-throughput fluorescence imaging approaches for drug discovery using in vitro and in vivo three-dimensional models NJ Martinez, SA Titus, AK Wagner, A Simeonov Expert opinion on drug discovery 10 (12), 1347-1361, 2015 | 60 | 2015 |
Mammalian mitochondrial and cytosolic folylpolyglutamate synthetase maintain the subcellular compartmentalization of folates SA Lawrence, SA Titus, J Ferguson, AL Heineman, SM Taylor, RG Moran Journal of Biological Chemistry 289 (42), 29386-29396, 2014 | 57 | 2014 |
Inhibition of PIP4Kγ ameliorates the pathological effects of mutant huntingtin protein I Al-Ramahi, SSP Giridharan, YC Chen, S Patnaik, N Safren, J Hasegawa, ... elife 6, e29123, 2017 | 55 | 2017 |
Functional analysis of a mouse brain Elk-type K+ channel MC Trudeau, SA Titus, JL Branchaw, B Ganetzky, GA Robertson Journal of Neuroscience 19 (8), 2906-2918, 1999 | 53 | 1999 |
Molecular analysis of murine leukemia cell lines resistant to 5, 10-dideazatetrahydrofolate identifies several amino acids critical to the function of folylpolyglutamate synthetase R Zhao, S Titus, F Gao, RG Moran, ID Goldman Journal of Biological Chemistry 275 (34), 26599-26606, 2000 | 52 | 2000 |
Identification of quaternary ammonium compounds as potent inhibitors of hERG potassium channels M Xia, SA Shahane, R Huang, SA Titus, E Shum, Y Zhao, N Southall, ... Toxicology and applied pharmacology 252 (3), 250-258, 2011 | 45 | 2011 |
Canvass: A crowd-sourced, natural-product screening library for exploring biological space SE Kearney, G Zahoránszky-Kőhalmi, KR Brimacombe, MJ Henderson, ... ACS central science 4 (12), 1727-1741, 2018 | 37 | 2018 |
Neural stem cells for disease modeling and evaluation of therapeutics for infantile (CLN1/PPT1) and late infantile (CLN2/TPP1) neuronal ceroid lipofuscinoses N Sima, R Li, W Huang, M Xu, J Beers, J Zou, S Titus, EA Ottinger, ... Orphanet journal of rare diseases 13, 1-14, 2018 | 36 | 2018 |
Tissue-specific expression of functional isoforms of mouse folylpoly-γ-glutamate synthetase: a basis for targeting folate antimetabolites FB Turner, JL Andreassi, J Ferguson, S Titus, A Tse, SM Taylor, ... Cancer research 59 (24), 6074-6079, 1999 | 32 | 1999 |
A high-content assay enables the automated screening and identification of small molecules with specific ALDH1A1-inhibitory activity A Yasgar, SA Titus, Y Wang, C Danchik, SM Yang, V Vasiliou, A Jadhav, ... PLoS One 12 (1), e0170937, 2017 | 31 | 2017 |