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George Ueda
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Quadrivalent influenza nanoparticle vaccines induce broad protection
S Boyoglu-Barnum, D Ellis, RA Gillespie, GB Hutchinson, YJ Park, ...
Nature 592 (7855), 623-628, 2021
2042021
Accurate computational design of multipass transmembrane proteins
P Lu, D Min, F DiMaio, KY Wei, MD Vahey, SE Boyken, Z Chen, JA Fallas, ...
Science 359 (6379), 1042-1046, 2018
1692018
Computational design of self-assembling cyclic protein homo-oligomers
JA Fallas, G Ueda, W Sheffler, V Nguyen, DE McNamara, B Sankaran, ...
Nature chemistry 9 (4), 353-360, 2017
1542017
Computational design of self-assembling cyclic protein homo-oligomers
JA Fallas, G Ueda, W Sheffler, V Nguyen, DE McNamara, B Sankaran, ...
Nature chemistry 9 (4), 353-360, 2017
1542017
Tailored design of protein nanoparticle scaffolds for multivalent presentation of viral glycoprotein antigens
G Ueda, A Antanasijevic, JA Fallas, W Sheffler, J Copps, D Ellis, ...
Elife 9, e57659, 2020
1302020
Designed proteins assemble antibodies into modular nanocages
R Divine, HV Dang, G Ueda, JA Fallas, I Vulovic, W Sheffler, S Saini, ...
Science 372 (6537), eabd9994, 2021
1152021
Topological control of cytokine receptor signaling induces differential effects in hematopoiesis
K Mohan, G Ueda, AR Kim, KM Jude, JA Fallas, Y Guo, M Hafer, Y Miao, ...
Science 364 (6442), eaav7532, 2019
1072019
Multivalent designed proteins neutralize SARS-CoV-2 variants of concern and confer protection against infection in mice
AC Hunt, JB Case, YJ Park, L Cao, K Wu, AC Walls, Z Liu, JE Bowen, ...
Science translational medicine 14 (646), eabn1252, 2022
692022
Structural and functional evaluation of de novo-designed, two-component nanoparticle carriers for HIV Env trimer immunogens
A Antanasijevic, G Ueda, PJM Brouwer, J Copps, D Huang, JD Allen, ...
PLoS Pathogens 16 (8), e1008665, 2020
552020
Computational design of mechanically coupled axle-rotor protein assemblies
A Courbet, J Hansen, Y Hsia, N Bethel, YJ Park, C Xu, A Moyer, ...
Science 376 (6591), 383-390, 2022
432022
Targeting HIV Env immunogens to B cell follicles in nonhuman primates through immune complex or protein nanoparticle formulations
JT Martin, CA Cottrell, A Antanasijevic, DG Carnathan, BJ Cossette, ...
npj Vaccines 5 (1), 72, 2020
422020
Generation of ordered protein assemblies using rigid three-body fusion
I Vulovic, Q Yao, YJ Park, A Courbet, A Norris, F Busch, A Sahasrabuddhe, ...
Proceedings of the National Academy of Sciences 118 (23), e2015037118, 2021
322021
Elicitation of broadly protective immunity to influenza by multivalent hemagglutinin nanoparticle vaccines
S Boyoglu-Barnum, D Ellis, RA Gillespie, GB Hutchinson, YJ Park, ...
bioRxiv, 2020.05. 30.125179, 2020
282020
Multivalent designed proteins protect against SARS-CoV-2 variants of concern
AC Hunt, JB Case, YJ Park, L Cao, K Wu, AC Walls, Z Liu, JE Bowen, ...
BioRxiv, 2021
152021
F‐domain valency determines outcome of signaling through the angiopoietin pathway
YT Zhao, JA Fallas, S Saini, G Ueda, L Somasundaram, Z Zhou, ...
EMBO reports 22 (12), e53471, 2021
132021
Nanoparticle display of prefusion coronavirus spike elicits S1-focused cross-reactive antibody response against diverse coronavirus subgenera
GB Hutchinson, OM Abiona, CT Ziwawo, AP Werner, D Ellis, Y Tsybovsky, ...
Nature Communications 14 (1), 6195, 2023
52023
Big data, big future
J Martin
BioTechniques 68 (4), 166-168, 2020
42020
Computational design of nanoscale rotational mechanics in de novo protein assemblies
A Courbet, J Hansen, Y Hsia, N Bethel, YJ Park, C Xu, A Moyer, ...
bioRxiv, 2021.11. 11.468255, 2021
22021
De novo design of modular protein hydrogels with programmable intra-and extracellular viscoelasticity
R Mout, RC Bretherton, J Decarreau, S Lee, N Gregorio, NI Edman, ...
Proceedings of the National Academy of Sciences 121 (6), e2309457121, 2024
12024
Antigen spacing on protein nanoparticles influences antibody responses to vaccination
D Ellis, A Dosey, S Boyoglu-Barnum, YJ Park, R Gillespie, H Syeda, ...
Cell reports 42 (12), 2023
12023
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